scholarly journals Elevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease

2016 ◽  
Vol Volume 11 ◽  
pp. 2369-2376 ◽  
Author(s):  
Fuqiang Wen ◽  
Hao Wang ◽  
Ting Yang ◽  
Diandian Li ◽  
Yanqiu Wu ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Lung Function ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Systemic Inflammation ◽  
Chronic Obstructive ◽  
Lung Function Decline ◽  
Obstructive Pulmonary Disease ◽  
Small Airway Obstruction ◽  
Pai 1

scholarly journals Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease

2000 ◽  
Vol 7 (3) ◽  
pp. 282-285 ◽  
Author(s):  
Joseph Milic-Emili
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Lung Function ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Exercise Tolerance ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Peripheral Muscle ◽  
Past Half Century

During the past half-century, many studies have investigated the correlation of exercise tolerance to routine lung function in patients with obstructive pulmonary disease. In virtually all of these studies, the degree of airway obstruction was assessed in terms of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Because in most studies only a weak correlation was found between exercise tolerance and degree of airway obstruction, it has been concluded that factors other than lung function impairment (eg, deconditioning and peripheral muscle dysfunction) play a predominant role in limiting exercise capacity in patients with chronic airway obstruction. Recent work, however, suggests that in patients with chronic obstructive pulmonary disease, the inspiratory capacity is a more powerful predictor of exercise tolerance than FEV1 and FVC.

scholarly journals Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1357 ◽  
Author(s):  
Egeria Scoditti ◽  
Marika Massaro ◽  
Sergio Garbarino ◽  
Domenico Maurizio Toraldo
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Lung Function ◽  
Pulmonary Disease ◽  
Dietary Patterns ◽  
Scientific Evidence ◽  
Chronic Obstructive ◽  
Lung Function Decline ◽  
Obstructive Pulmonary Disease ◽  
Prevention And Treatment ◽  
The Impact

Chronic obstructive pulmonary disease is one of the leading causes of morbidity and mortality worldwide and a growing healthcare problem. Identification of modifiable risk factors for prevention and treatment of COPD is urgent, and the scientific community has begun to pay close attention to diet as an integral part of COPD management, from prevention to treatment. This review summarizes the evidence from observational and clinical studies regarding the impact of nutrients and dietary patterns on lung function and COPD development, progression, and outcomes, with highlights on potential mechanisms of action. Several dietary options can be considered in terms of COPD prevention and/or progression. Although definitive data are lacking, the available scientific evidence indicates that some foods and nutrients, especially those nutraceuticals endowed with antioxidant and anti-inflammatory properties and when consumed in combinations in the form of balanced dietary patterns, are associated with better pulmonary function, less lung function decline, and reduced risk of COPD. Knowledge of dietary influences on COPD may provide health professionals with an evidence-based lifestyle approach to better counsel patients toward improved pulmonary health.

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

2004 ◽  
Vol 350 (26) ◽  
pp. 2645-2653 ◽  
Author(s):  
James C. Hogg ◽  
Fanny Chu ◽  
Soraya Utokaparch ◽  
Ryan Woods ◽  
W. Mark Elliott ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Small Airway ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Small Airway Obstruction

scholarly journals Individualized prediction of lung-function decline in chronic obstructive pulmonary disease

2016 ◽  
Vol 188 (14) ◽  
pp. 1004-1011 ◽  
Author(s):  
Zafar Zafari ◽  
Don D. Sin ◽  
Dirkje S. Postma ◽  
Claes-Göran Löfdahl ◽  
Judith Vonk ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Lung Function ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Lung Function Decline ◽  
Obstructive Pulmonary Disease ◽  
Individualized Prediction
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