scholarly journals Is extended-field concurrent chemoradiation an option for radiologic negative paraaortic lymph node, locally advanced cervical cancer?

2014 ◽  
pp. 339 ◽  
Author(s):  
Mutahir Tunio ◽  
Mushabbab Al-Asiri ◽  
Abdulrehman AlHadab ◽  
Reham Mohamed ◽  
Yasser Bayoumi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Locally Advanced ◽  
Concurrent Chemoradiation ◽  
Advanced Cervical Cancer ◽  
Paraaortic Lymph Node ◽  
Locally Advanced Cervical Cancer ◽  
Extended Field

Number of paraaortic lymph node dissections as a prognostic factor in locally advanced cervical cancer

2020 ◽  
Vol 155 (5) ◽  
pp. 197-201
Author(s):  
Inmaculada Nicolás ◽  
Juan Gilabert-Estellés ◽  
Juan Gilabert-Aguilar ◽  
Pere Fusté ◽  
Kristina Aghababyan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Locally Advanced ◽  
Advanced Cervical Cancer ◽  
Paraaortic Lymph Node ◽  
Locally Advanced Cervical Cancer

Number of paraaortic lymph node dissections as a prognostic factor in locally advanced cervical cancer

2020 ◽  
Vol 155 (5) ◽  
pp. 197-201
Author(s):  
Inmaculada Nicolás ◽  
Juan Gilabert-Estellés ◽  
Juan Gilabert-Aguilar ◽  
Pere Fusté ◽  
Kristina Aghababyan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Locally Advanced ◽  
Advanced Cervical Cancer ◽  
Paraaortic Lymph Node ◽  
Locally Advanced Cervical Cancer

scholarly journals PD-0437: Impact of lymph node dose on nodal control in patients with locally advanced cervical cancer

2015 ◽  
Vol 115 ◽  
pp. S213-S214
Author(s):  
A. Ramlov ◽  
P.S. Kroon ◽  
I. Jürgenliemk_Schulz ◽  
A. De Leeuw ◽  
L. Fokdal ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Locally Advanced ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Nodal Control

Extended-field irradiation for locally advanced cervical cancer

2016 ◽  
Author(s):  
Komsan Thamronganantasakul ◽  
Narudom Supakalin ◽  
Chumnan Kietpeerakool ◽  
Porjai Pattanittum ◽  
Pisake Lumbiganon
Keyword(s):  
Cervical Cancer ◽  
Locally Advanced ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Extended Field

The role of additional hysterectomy after concurrent chemoradiation for patients with locally advanced cervical cancer

2019 ◽  
Vol 25 (2) ◽  
pp. 384-390 ◽  
Author(s):  
Kosuke Yoshida ◽  
Hiroaki Kajiyama ◽  
Masato Yoshihara ◽  
Satoshi Tamauchi ◽  
Yoshiki Ikeda ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Locally Advanced ◽  
Concurrent Chemoradiation ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer

scholarly journals Concurrent chemoradiation in treatment of carcinoma cervix

1970 ◽  
Vol 2 (1) ◽  
pp. 4-8
Author(s):  
Meeta Singh ◽  
Rajshree Jha ◽  
Josie Baral ◽  
Suniti Rawal
Keyword(s):  
Cervical Cancer ◽  
Radiation Therapy ◽  
Cervical Carcinoma ◽  
Locally Advanced ◽  
Concurrent Chemoradiation ◽  
Advanced Cervical Cancer ◽  
European Organization ◽  
Locally Advanced Cervical Cancer ◽  
Advanced Cervical Carcinoma ◽  
To Come

Aim: to compare if concurrent chemoradiation is better than radiotherapy given alone in the treatment of women with locally advanced cervical cancer from published literature Method: Study Design: Randomized control trials of > than 2, 403 women participants who underwent treatment for advanced cervical carcinoma mainly in two huge center i.e. from National Cancer Institute (NCI), USA and European Organization for Research and Treatment of Cancer (EORTC) were reviewed regarding the treatment they received at the center: concurrent chemoradiation/ radiation therapy alone. The results were analyzed to come to conclusion. Result demonstrated a 30-50% improvement in survival when cisplatin-based chemotherapy in NCI or 5 fluorouracil and cisplatin based chemotherapy was used in EORTC was administered with concurrent radiation therapy (chemoradiation) Conclusions: The addition of chemotherapy (cisplatin) in NCI and (cisplatin and fluorouracil) in the EORTC for the treatment of locally advanced cervical cancer with the concurrent chemoradition have elicited better survival than those treated with radiotherapy alone dittoed by several other trials which can be anticipated to benefit Nepalese women with locally advanced cervical carcinoma. Key-words: Cancer cervix, chemoradiation, radiotherapy   doi:10.3126/njog.v2i1.1467 N. J. Obstet. Gynaecol Vol. 2, No. 1, p. 4 - 8 May -June 2007

scholarly journals Reduction of dose to duodenum with a refined delineation method of Para-aortic region in patients with locally advanced cervical Cancer receiving prophylactic extended-field radiotherapy

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Bo Yang ◽  
Xiaoliang Liu ◽  
Ke Hu ◽  
Jie Qiu ◽  
Fuquan Zhang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Irradiation Dose ◽  
Locally Advanced ◽  
Volumetric Modulated Arc Therapy ◽  
Vena Cava ◽  
Target Volume ◽  
High Dose ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Extended Field

Abstract Background To compare irradiation dose to the second and third portions of duodenum (Duo2 and Duo3) with a new refined and old delineation method of para-aortic region for patients with locally advanced cervical cancer (LACC) receiving prophylactic extended-field radiotherapy (EFRT). Methods Twenty consecutive patients with LACC were treated with prophylactic EFRT from January 2016 to January 2017 at our institute. Two delineation methods of para-aortic region were designed for each patient, the old delineation method ensured a full coverage of aortic and inferior vena cava, while the right paracaval region above L3 was omitted from CTV in the new delineation method. Patients received a dose of 50.4Gy in 28 fractions for PCTV and a dose of 60.2Gy in 28 fractions for PGTV with volumetric-modulated arc therapy (VMRT). The dose delivered to Duo2 and Duo3 with these two delineation methods were compared. Results All treatment plans achieved excellent target volume coverage with 95% of PCTV receiving 50.4Gy and 95% of PGTV receiving 60.2Gy. There was no difference between delineation methods in low dose level (V5, V10, V15, V20, V25) for Duo2 and Duo3. The V30, V35, V40, V45, V50, Dmax, Dmean and D2cc for Duo2 with the new and old delineation methods were 55.76% vs 80.54% (P = 0.009), 34.72% vs 70.91% (P < 0.001), 18.69% vs 55.46% (P < 0.001), 8.20% vs 41.49% (P < 0.001), 1.86% vs 21.60% (P < 0.001), 49.58Gy vs 52.91Gy (P = 0.002), 30.38Gy vs 39.22Gy (P = 0.001) and 37.90Gy vs 48.64Gy (P < 0.001) respectively. For Duo3, the new delineation method achieved significant advantages in V30, V35, V40, V45, V50 and Dmean over the old one (96.82% vs 99.25%, P = 0.021; 89.65% vs 97.21%, P = 0.001; 79.50% vs 93.18%, P < 0.001; 65.63% vs 82.93%, P < 0.001; 43.39% vs 65.60%, P < 0.001; 46.09Gy vs 49.24Gy, P < 0.001), no deference was observed regarding D2cc and Dmax with these two delineation methods. Conclusion With the new delineation method of para-aortic area in prophylactic EFRT, significant reduction of irradiation dose to the second and third portions of duodenum in high dose area was obtained. This may further lower the incidence of duodenal toxicity when performing prophylactic EFRT for patients with LACC.

Sign in / Sign up

Export Citation Format

Share Document