scholarly journals Radiation Oncologists’ Approach to Internal Mammary Lymph Node Radiotherapy in Breast Cancer: The Turkish Society for Radiation Oncology Breast Cancer Study Group (TROD 06-005 Survey Study)

2021 ◽  
Vol Volume 13 ◽  
pp. 7203-7212
Author(s):  
Ayfer Ay Eren ◽  
Mehmet Fuat Eren
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Radiation Oncology ◽  
Survey Study ◽  
Study Group ◽  
Internal Mammary Lymph Node ◽  
Cancer Study Group ◽  
Breast Cancer Study ◽  
Internal Mammary ◽  
Turkish Society

scholarly journals Temporary Implant Irradiation: Survey of Turkish Society of Radiation Oncology Breast Cancer Study Group

2021 ◽  
Vol 17 (1) ◽  
pp. 21-27
Author(s):  
Nuri Kaydıhan ◽  
Gül Alço ◽  
Mustafa Şükrü Şenocak ◽  
Nuran Beşe
Keyword(s):  
Breast Cancer ◽  
Radiation Oncology ◽  
Study Group ◽  
Cancer Study ◽  
Cancer Study Group ◽  
Breast Cancer Study ◽  
Turkish Society

Site of Primary Tumor Has a Prognostic Role in Operable Breast Cancer: The International Breast Cancer Study Group Experience

2005 ◽  
Vol 23 (7) ◽  
pp. 1390-1400 ◽  
Author(s):  
Marco Colleoni ◽  
David Zahrieh ◽  
Richard D. Gelber ◽  
Stig B. Holmberg ◽  
Jan E. Mattsson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Axillary Lymph Node ◽  
Study Group ◽  
Axillary Lymph ◽  
Node Negative ◽  
Cancer Study ◽  
Cancer Study Group ◽  
Breast Cancer Study ◽  
Significant Difference

Purpose Cancer presenting at the medial site of the breast may have a worse prognosis compared with tumors located in external quadrants. For medial tumors, axillary lymph node staging may not accurately reflect the metastatic potential of the disease. Patients and Methods Eight-thousand four-hundred twenty-two patients randomly assigned to International Breast Cancer Study Group clinical trials between 1978 and 1999 were classified as medial site (1,622; 19%) or lateral, central, and other sites (6,800; 81%). Median follow-up was 11 years. Results A statistically significant difference was observed for patients with medial tumors versus those with nonmedial tumors in disease-free survival (DFS; 10-year DFS, 46% v 48%; HR, 1.10; 95% CI, 1.02 to 1.18; P = .01) and overall survival (10-year OS 59% v 61%; HR, 1.09; 1.01 to 1.19; P = .04). This difference increased after adjustment for other prognostic factors (HR, 1.22; 95% CI, 1.13 to 1.32 for DFS; and HR, 1.24; 95% CI, 1.14 to 1.35 for OS; both P = .0001). The risk of relapse for patients with medial presentation was largest for the node-negative cohort and for patients with tumors larger than 2 cm. In the subgroup of 2,931 patients with negative axillary lymph nodes, 10-year DFS was 61% v 67%, and OS was 73% v 80% for medial versus nonmedial sites, respectively (HR 1.33; 95% CI, 1.15 to 1.54; P = .0001 for DFS; and HR 1.40; 95% CI, 1.17 to 1.67; P = .0003 for OS). Conclusion Tumor site has a significant prognostic utility, especially for axillary lymph node–negative disease, that should be considered in therapeutic algorithms. New staging procedures such as biopsy of the sentinel internal mammary nodes or novel imaging methods should be further studied in patients with medial tumors.

Internal Mammary Lymph Node Drainage Patterns in Patients With Breast Cancer Documented by Breast Lymphoscintigraphy

2001 ◽  
Vol 8 (3) ◽  
pp. 234-240 ◽  
Author(s):  
David R. Byrd ◽  
Lisa K. Dunnwald ◽  
David A. Mankoff ◽  
Benjamin O. Anderson ◽  
Roger E. Moe ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Internal Mammary Lymph Node ◽  
Drainage Patterns ◽  
Internal Mammary
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