scholarly journals Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway

2020 ◽  
Vol Volume 12 ◽  
pp. 3081-3089 ◽  
Author(s):  
Guangxiu Guo ◽  
Sujuan Dai ◽  
Qing Chen
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Breast Cancer Cells ◽  
And Migration ◽  
Proliferation And Migration

Long noncoding RNA KCNQ1OT1 is correlated with human breast cancer cell development through inverse regulation of hsa-miR-107

2020 ◽  
Vol 98 (3) ◽  
pp. 338-344 ◽  
Author(s):  
Yanyan Wu ◽  
Qing-Jun Bi ◽  
Rui Han ◽  
Yajie Zhang
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Breast Cancer Cells ◽  
And Migration ◽  
Proliferation And Migration

In this work, we investigated the expression pattern and regulatory function of long noncoding RNA (lncRNA) KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1) in breast cancer. We found that KCNQ1OT1 was significantly upregulated in breast cancer cell lines. In lentiviral-transduced BT-549 and HCC1599 cells, KCNQ1OT1 knockdown impaired cancer cell functions, including in vitro proliferation and migration, and in vivo transplant growth. The possible sponging target of KCNQ1OT1, human microRNA-107 (hsa-miR-107), was confirmed to be bound by KCNQ1OT1, and was upregulated in breast cancer cells with KCNQ1OT1 downregulation. Further, hsa-miR-107 knockdown in KCNQ1OT1-downregulated cancer cells reversed its impairing effects on cancer cell proliferation and migration in vitro. Thus, loss of KCNQ1OT1 is associated with functional impairment in breast cancer cells, likely through inverse regulation of its sponging target, hsa-miR-107.

scholarly journals miR-145 inhibits proliferation and migration of breast cancer cells by directly or indirectly regulating TGF-β1 expression

2017 ◽  
Vol 50 (5) ◽  
pp. 1701-1710 ◽  
Author(s):  
Yanling Ding ◽  
Chunfu Zhang ◽  
Jiahui Zhang ◽  
Nannan Zhang ◽  
Tao Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
And Migration ◽  
Tgf Β1 ◽  
Proliferation And Migration

scholarly journals MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells

EMBO Reports ◽  
2017 ◽  
Vol 18 (3) ◽  
pp. 420-436 ◽  
Author(s):  
Emad Heidary Arash ◽  
Ahmed Shiban ◽  
Siyuan Song ◽  
Liliana Attisano
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Hippo Signaling ◽  
And Migration ◽  
Proliferation And Migration

scholarly journals Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15

2019 ◽  
Vol 145 (9) ◽  
pp. 2478-2487 ◽  
Author(s):  
Liang‐Chih Liu ◽  
Yuan‐Liang Wang ◽  
Pei‐Le Lin ◽  
Xiang Zhang ◽  
Wei‐Chung Cheng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Breast Cancer Cells
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