scholarly journals Synergistic Effect Between Full-Term Pregnancy/Breastfeeding And Familial Susceptibility On Breast Cancer Risk

2019 ◽  
Vol Volume 11 ◽  
pp. 9743-9748 ◽  
Author(s):  
Huan Lin ◽  
Jiahuai Wen ◽  
Lixia Hong ◽  
Ying Chen ◽  
Yannan Wu ◽  
...  
2000 ◽  
Vol 151 (7) ◽  
pp. 715-722 ◽  
Author(s):  
W.-C. Chie ◽  
C.-c. Hsieh ◽  
P. A. Newcomb ◽  
M. P Longnecker ◽  
R. Mittendorf ◽  
...  

2016 ◽  
Vol 27 (9) ◽  
pp. 1167-1174 ◽  
Author(s):  
Harindra Jayasekara ◽  
Robert J. MacInnis ◽  
Allison M. Hodge ◽  
Robin Room ◽  
Roger L. Milne ◽  
...  

2005 ◽  
Vol 161 (Supplement_1) ◽  
pp. S57-S57
Author(s):  
K C Johnson ◽  
M S C Conlon ◽  
S Pan ◽  
Y Mao ◽  

2015 ◽  
Vol 56 (2) ◽  
pp. 545-555 ◽  
Author(s):  
Maria G. Kakkoura ◽  
Maria A. Loizidou ◽  
Christiana A. Demetriou ◽  
Giorgos Loucaides ◽  
Maria Daniel ◽  
...  

Author(s):  
Amir Shamshirian ◽  
Keyvan Heydari ◽  
Zahra Shams ◽  
Amir Reza Aref ◽  
Danial Shamshirian ◽  
...  

AbstractObjectivesBreast cancer is known as one of the deadliest forms of cancer, and it is increasing globally. There are a variety of proven and controversial risk factors for this malignancy. Herein, we aimed to undertake a systematic review and meta-analysis focus on the epidemiology of breast cancer risk factors in Iran.MethodsWe performed a systematic search via PubMed, Scopus, Web of Science, and Persian databases for identifying studies published on breast cancer risk factors up to March 2019. Meta-analyses were done for risk factors reported in more than one study. We calculated odds ratios (ORs) with corresponding 95% confidence intervals (CIs) using a fixed/random-effects models.ResultsThirty-nine studies entered into the meta-analysis. Pooling of ORs showed a significant harmful effect for risk factors including family history (OR: 1.80, 95%CI 1.47–2.12), hormonal replacement therapy (HRT) (OR: 5.48, 95%CI 0.84–1.74), passive smokers (OR: 1.68, 95%CI 1.34–2.03), full-term pregnancy at age 30 (OR: 3.41, 95%CI 1.19–5.63), abortion (OR: 1.84, 95%CI 1.35–2.33), sweets consumption (OR: 1.71, 95%CI 1.32–2.11) and genotype Arg/Arg (crude OR: 1.59, 95%CI 1.07–2.10), whereas a significant protective effect for late menarche (OR: 0.58, 95%CI 0.32–0.83), nulliparity (OR: 0.68, 95%CI 0.39–0.96), 13–24 months of breastfeeding (OR: 0.68, 95%CI 0.46–0.90), daily exercise (OR: 0.59, 95%CI 0.44–0.73) and vegetable consumption (crude OR: 0.28, 95%CI 0.10–0.46).ConclusionsThis study suggests that factors such as family history, HRT, passive smokers, late full-term pregnancy, abortion, sweets consumption and genotype Arg/Arg might increase risk of breast cancer development, whereas late menarche, nulliparity, 13–24 months breastfeeding, daily exercise and vegetable consumption had an inverse association with breast cancer development.


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