scholarly journals The predictive value of high-density lipoprotein for ocular metastases in colorectal cancer patients

2019 ◽  
Vol Volume 11 ◽  
pp. 3511-3519 ◽  
Author(s):  
Pei-Wen Zhu ◽  
Ying-Xin Gong ◽  
You-Lan Min ◽  
Qi Lin ◽  
Biao Li ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
High Density Lipoprotein ◽  
Cancer Patients ◽  
Predictive Value ◽  
Density Lipoprotein ◽  
High Density ◽  
Ocular Metastases ◽  
Colorectal Cancer Patients

scholarly journals The preablation monocyte/ high density lipoprotein ratio predicts the late recurrence of paroxysmal atrial fibrillation after radiofrequency ablation

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
She-an Chen ◽  
Man-man Zhang ◽  
Meifang Zheng ◽  
Fei Liu ◽  
Lei Sun ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Radiofrequency Ablation ◽  
High Density Lipoprotein ◽  
Predictive Value ◽  
Density Lipoprotein ◽  
Late Recurrence ◽  
High Density ◽  
Significant Difference ◽  
Af Recurrence

Abstract Background The monocyte/high-density lipoprotein ratio (MHR) has emerged as a promising alternative biomarker in the fields of cardiovascular disease and atrial fibrillation (AF). This retrospective study was aimed to explore the predictive value of the MHR for the late recurrence of AF after radiofrequency ablation. Methods From April 2015 to October 2018, patients with paroxysmal AF who had undergone radiofrequency catheter ablation at Subei People’s Hospital of Jiangsu Province were enrolled in our study. All the participants were observed until November 2019 after the procedure. During the postoperative follow up, the patients were categorized into the recurrence group and maintenance of sinus rhythm group based on who had experienced AF recurrence. Results One hundred twenty-five patients were diagnosed with paroxysmal AF, with an average age of 61.2 ± 9.3 years. Forty-seven patients had developed late recurrence during a mean follow up of 25.1 ± 12.0 months. The AF recurrence event rates were significantly increased in the highest MHR tertile compared with those in the lowest MHR tertile (22.0% vs. 57.1%; P < 0.05). On multivariate logistic regression analysis, the preablation MHR (OR = 1.34; 95% CI = 1.12 ~ 1.60; P = 0.001) and left atrial diameter (LAD) (OR = 1.21, 95% CI = 1.08 ~ 1.35; P = 0.001) were independent risk factors predicting the recurrence of AF after radiofrequency ablation. Furthermore, receiver operating characteristic (ROC) curve analysis revealed that the area under the curve (AUC) of the MHR was 0.712 (95% CI = 0.618 ~ 0.806; P = 0.000) and that of LAD was 0.739 (95% CI = 0.653 ~ 0.814; P = 0.000). Z-test found no significant difference between the MHR and LAD regarding the AUC (Z = 0.451; P = 0.652). Conclusion An elevated preablation MHR was associated with an increased risk of the postoperative recurrence of AF. Additionally, the MHR independently predicted the late recurrence of paroxysmal AF after radiofrequency ablation, with the same predictive value as LAD.

P056 High-density lipoprotein (HDL) subfractions and progesterone receptor in breast cancer patients

The Breast ◽  
2015 ◽  
Vol 24 ◽  
pp. S46
Author(s):  
V.G. Flote ◽  
R. Vettukattil ◽  
T. Egeland ◽  
A. Mctiernan ◽  
H. Frydenberg ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Progesterone Receptor ◽  
High Density Lipoprotein ◽  
Cancer Patients ◽  
Density Lipoprotein ◽  
High Density ◽  
Breast Cancer Patients ◽  
Hdl Subfractions

scholarly journals Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients

BMC Cancer ◽  
2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Tjaša Vižin ◽  
Ib Jarle Christensen ◽  
Michael Wilhelmsen ◽  
Hans Jørgen Nielsen ◽  
Janko Kos
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Predictive Value ◽  
Cathepsin X ◽  
Colorectal Cancer Patients

scholarly journals Compared with the monocyte to high-density lipoprotein ratio (MHR) and the neutrophil to lymphocyte ratio (NLR), the neutrophil to high-density lipoprotein ratio (NHR) is more valuable for assessing the inflammatory process in Parkinson’s disease

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhu Liu ◽  
Qingli Fan ◽  
Shizheng Wu ◽  
Yaqi Wan ◽  
Yancheng Lei
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
High Density Lipoprotein ◽  
Predictive Value ◽  
Disease Duration ◽  
Density Lipoprotein ◽  
High Density ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
Lymphocyte Ratio

Abstract Background The inflammatory response plays essential roles in the pathological process and prognosis of Parkinson’s disease (PD). This research investigated the predictive value of the neutrophil to high-density lipoprotein ratio (NHR), neutrophil to lymphocyte ratio (NLR), and monocyte to high-density lipoprotein ratio (MHR) for PD. Methods Patients with PD (n = 98) were divided into three groups according to disease duration: < 6 years (n = 55), 6–10 years (n = 29) and > 10 years (n = 14). Based on the classification system of Hoehn and Yahr, grades 1 ~ 2.5 were considered early-stage PD (n = 44), and grades 3 ~ 5 were considered advanced-stage PD (n = 54). In addition, healthy subjects (n = 98) matched to the above PD patients in the same period were selected as the control group. Differences in the NHR, NLR, MHR and other indicators among the groups were evaluated. Results Smoking, drinking, the neutrophil count and the NHR and NLR were remarkably greater and hypertension, index of body mass, the lymphocyte count, and the levels of cholesterol in total, triglycerides, lipoprotein cholesterol with low density and uric acid were sharply lower in the PD group compared with in the control group. Analysis of multifactor logistic regression indicated that the NHR (odds ratio (adjusted OR) = 1.576, 95% CI: 1.053 ~ 2.358, P = 0.027) and NLR (adjusted OR = 1.734, 95% CI: 1.046 ~ 2.876, P = 0.033) were factors of risk for PD, while the MHR was not significantly correlated with PD. The areas under the receiver operating characteristic (ROC) curve (AUCs) for the prediction of PD by the NHR and NLR were 0.654 (95% CI: 0.583 ~ 0.721, P = 0.0001) and 0.69 (95% CI: 0.62 ~ 0.754, P < 0.0001), respectively, and the optimal cutoff values were 1.848 × 109/mmol and 2.62 × 109/mmol. Spearman’s correlation analysis indicated that the NHR was correlated with the disease duration significantly negatively and that the MHR was positively correlated with disease severity. Conclusions In summary, the NHR not only has strong predictive value for PD but is also closely related to disease duration. The NHR may be a better prediction for the long-period clinical results in PD patients than the MHR and NLR. Trial registration Clinical medical reserach center project of Qinghai Province (2017-SF-L1).

Predictive value of ERCC1, ERCC2, and XRCC1 overexpression for stage III colorectal cancer patients receiving FOLFOX-4 adjuvant chemotherapy

2013 ◽  
Vol 108 (7) ◽  
pp. 457-464 ◽  
Author(s):  
Ming-Yii Huang ◽  
Hsiang-Lin Tsai ◽  
Chih-Hung Lin ◽  
Ching-Wen Huang ◽  
Cheng-Jen Ma ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Predictive Value ◽  
Stage Iii ◽  
Colorectal Cancer Patients
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