scholarly journals Assessment of functional variants and expression of long noncoding RNAs in vitamin D receptor signaling in breast cancer

2018 ◽  
Vol Volume 10 ◽  
pp. 3451-3462 ◽  
Author(s):  
Vahid Kholghi Oskooei ◽  
Lobat Geranpayeh ◽  
Mir Davood Omrani ◽  
Soudeh Ghafouri-Fard
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Vitamin D Receptor ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Receptor Signaling ◽  
Functional Variants

scholarly journals Altered Nuclear Receptor Corepressor Expression Attenuates Vitamin D Receptor Signaling in Breast Cancer Cells

2006 ◽  
Vol 12 (7) ◽  
pp. 2004-2013 ◽  
Author(s):  
Claire M. Banwell ◽  
Donia P. MacCartney ◽  
Michelle Guy ◽  
Alice E. Miles ◽  
Milan R. Uskokovic ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Cells ◽  
Nuclear Receptor ◽  
Vitamin D Receptor ◽  
Breast Cancer Cells ◽  
Receptor Signaling ◽  
Nuclear Receptor Corepressor

Deprivation of the vitamin D receptor (VDR) fuels breast cancer metastases to bone

2019 ◽  
Author(s):  
K Horas ◽  
M Abraham ◽  
F Jakob ◽  
R Ebert ◽  
G Maier ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Vitamin D Receptor ◽  
Breast Cancer Metastases ◽  
Cancer Metastases

scholarly journals The Role of lncRNA in the Development of Tumors, Including Breast Cancer

2021 ◽  
Vol 22 (16) ◽  
pp. 8427
Author(s):  
Beata Smolarz ◽  
Anna Zadrożna-Nowak ◽  
Hanna Romanowicz
Keyword(s):  
Breast Cancer ◽  
Breast Carcinoma ◽  
Present Article ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Regulation Of Transcription ◽  
Ribonucleic Acids ◽  
Detailed Review ◽  
Cellular Processes

Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules seems to be of great importance for the proper functioning of the organism. Studies have shown a relationship between disturbed lncRNA expression and the pathogenesis of many diseases, including cancer. The present article presents a detailed review of the latest reports and data regarding the importance of lncRNA in the development of cancers, including breast carcinoma.

scholarly journals m6A-induced LINC00958 promotes breast cancer tumorigenesis via the miR-378a-3p/YY1 axis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Dongwen Rong ◽  
Qian Dong ◽  
Huajun Qu ◽  
Xinna Deng ◽  
Fei Gao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Progression ◽  
Human Breast Cancer ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Human Breast ◽  
Transcript Stability ◽  
Rna Transcript ◽  
Insight Into ◽  
Competitive Endogenous Rna

AbstractIncreasing evidence demonstrates that long noncoding RNAs (lncRNAs) play critical roles in human breast cancer (BC) tumorigenesis. However, the mechanisms by which lncRNA and N6-methyladenosine (m6A) regulate BC tumorigenesis are still unclear. In the present research, LINC00958 was markedly overexpressed in BC tissue and cells, and LINC00958 upregulation promoted the tumor progression of BC cells. Mechanistically, m6A methyltransferase-like 3 (METTL3) gave rise to the upregulation of LINC00958 by promoting its RNA transcript stability. Moreover, LINC00958 acted as a competitive endogenous RNA for miR-378a-3p to promote YY1. Overall, these data provide novel insight into how m6A-mediated LINC00958 regulates BC tumorigenesis.

Vitamin D Receptor (VDR) Allelic Variants Correlating with Response to Vitamin D3 Supplementation in Breast Cancer Survivors

2021 ◽  
pp. 1-14
Author(s):  
Elham Kazemian ◽  
Sayed Hossein Davoodi ◽  
Mohammad Esmaeil Akbari ◽  
Nariman Moradi ◽  
Safoora Gharibzadeh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Vitamin D Receptor ◽  
Vitamin D3 ◽  
Breast Cancer Survivors ◽  
Allelic Variants ◽  
Vitamin D3 Supplementation

scholarly journals Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer

2017 ◽  
Vol 5 (1) ◽  
pp. 23-34 ◽  
Author(s):  
Andrew J. Warburton ◽  
David N. Boone
Keyword(s):  
Breast Cancer ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas
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