scholarly journals Bimodality treatment of patients with pelvic adenoid cystic carcinoma with photon intensity-modulated radiotherapy plus carbon ion boost: a case series

2018 ◽  
Vol Volume 10 ◽  
pp. 583-588
Author(s):  
Denise Bernhardt ◽  
Florian Sterzing ◽  
Sebastian Adeberg ◽  
Klaus Herfarth ◽  
Sonja Katayama ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Case Series ◽  
Intensity Modulated Radiotherapy ◽  
Carbon Ion ◽  
Intensity Modulated ◽  
Adenoid Cystic ◽  
Photon Intensity

scholarly journals A treatment planning study of combined carbon ion-beam plus photon intensity-modulated radiotherapy

2020 ◽  
Vol 15 ◽  
pp. 16-22
Author(s):  
Christopher Schuppert ◽  
Angela Paul ◽  
Simeon Nill ◽  
Andrea Schwahofer ◽  
Jürgen Debus ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Ion Beam ◽  
Intensity Modulated Radiotherapy ◽  
Planning Study ◽  
Carbon Ion ◽  
Intensity Modulated ◽  
Photon Intensity ◽  
Carbon Ion Beam

Adenoid cystic carcinoma of trachea: long-term disease control after endoscopic surgery and radiotherapy

2019 ◽  
Author(s):  
Corrado Spatola ◽  
Alessandra Tocco ◽  
Dario Marletta ◽  
Roberto Milazzotto ◽  
Francesco Marletta ◽  
...  
Keyword(s):  
Disease Control ◽  
Adenoid Cystic Carcinoma ◽  
Intensity Modulated Radiotherapy ◽  
Neck Region ◽  
Intensity Modulated ◽  
Adenoid Cystic ◽  
The Impact

Aim: Adenoid cystic carcinoma is a rare tumor of head and neck region and its development in the thoracic region is even less frequent. This implies the absence of guidelines for therapeutic management and a consequent case-by-case approach. The role of radiotherapy is not yet clearly defined, but intensity-modulated radiotherapy allows for improved organ-at-risk sparing. Materials & methods: We have collected the cases of four patients treated at our institutions by the means of intensity-modulated radiotherapy, after endoscopic resection. Results & conclusion: Patients treated achieved long-term disease control of about 5 years, with a minimal acute toxicity. Longer follow-up is needed to drain conclusion on the impact of this treatment on overall survival.

scholarly journals Adenoid Cystic Carcinoma of the Trachea Treated with PET-CT Based Intensity Modulated Radiotherapy

2008 ◽  
Vol 3 (7) ◽  
pp. 793-795 ◽  
Author(s):  
Kunhi Parambath Haresh ◽  
Ramachandran Prabhakar ◽  
Goura K. Rath ◽  
Daya Nand Sharma ◽  
Pramod K. Julka ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Intensity Modulated Radiotherapy ◽  
Intensity Modulated ◽  
Adenoid Cystic ◽  
Pet Ct

scholarly journals Treatment Outcome of 227 Patients with Sinonasal Adenoid Cystic Carcinoma (ACC) after Intensity Modulated Radiotherapy and Active Raster-Scanning Carbon Ion Boost: A 10-Year Single-Center Experience

Cancers ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1705 ◽  
Author(s):  
Sati Akbaba ◽  
Dina Ahmed ◽  
Andreas Mock ◽  
Thomas Held ◽  
Suzan Bahadir ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Adenoid Cystic Carcinoma ◽  
Carbon Ion ◽  
Raster Scanning ◽  
Intensity Modulated ◽  
Adenoid Cystic ◽  
Long Term Treatment ◽  
Significant Difference ◽  
Grade 3

We aimed to evaluate the treatment outcome of primary and postoperative bimodal radiotherapy (RT) including intensity modulated photon radiotherapy (IMRT) and carbon ion radiotherapy (CIRT) for sinonasal adenoid cystic carcinoma (ACC) patients. Medical records of 227 consecutive patients who received either a primary (n = 90, 40%) or postoperative (n = 137, 60%; R2, n = 86, 63%) IMRT with doses between 48 and 56 Gy in 1.8 or 2 Gy fractions and active raster-scanning carbon ion boost with 18 to 24 Gy (RBE, relative biological effectiveness) in 3 Gy (RBE) fractions between 2009 and 2019 up to a median total dose of 80 Gy (EQD2, equivalent dose in 2 Gy single dose fractions, range 71–80 Gy) were reviewed. Results: Median follow-up was 50 months. In univariate and multivariate analysis, no significant difference in local control (LC) could be shown between the two treatment groups (p = 0.33). Corresponding 3-year LC rates were 79% for primary bimodal RT and 82% for postoperative bimodal RT, respectively. T4 stage (p = 0.002) and solid histology (p = 0.005) were identified as independent prognostic factors for decreased LC. Significant worse long-term treatment tolerance was observed for postoperatively irradiated patients with 17% vs. 6% late grade 3 toxicity (p < 0.001). Primary radiotherapy including IMRT and carbon ion boost for dose-escalation results in adequate LC with less long-term grade 3 toxicity compared to postoperative bimodal radiotherapy in sinonasal ACC patients. The high rate of macroscopic tumor disease in the postoperative group makes the interpretation of the beneficial results in LC for primary RT difficult.

Late-course accelerated hyperfractionated intensity-modulated radiotherapy for nasopharyngeal adenoid cystic carcinoma: A case report

2020 ◽  
Vol 45 (1) ◽  
pp. 46-51
Author(s):  
Dehuan Xie ◽  
Aoqiang Chen ◽  
Shaowen Lv ◽  
Huizhong Zhang ◽  
Xuekui Liu ◽  
...  
Keyword(s):  
Case Report ◽  
Adenoid Cystic Carcinoma ◽  
Intensity Modulated Radiotherapy ◽  
Intensity Modulated ◽  
Adenoid Cystic
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