scholarly journals Positive Predictive Value of Diagnostic Codes for Inflammatory Bowel Disease in the Danish National Patient Registry Among Individuals 50+ Years, Using Patient Records as Reference Standard

2021 ◽  
Vol Volume 13 ◽  
pp. 335-344
Author(s):  
Camilla Rye ◽  
Katrine Hass Rubin ◽  
Frederik Trier Moller ◽  
Mette Julsgaard ◽  
Tine Jess ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Positive Predictive Value ◽  
Bowel Disease ◽  
Patient Records ◽  
Reference Standard ◽  
National Patient Registry ◽  
Diagnostic Codes ◽  
Danish National Patient Registry ◽  
National Patient ◽  
Inflammatory Bowel

scholarly journals Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry

2018 ◽  
Vol Volume 10 ◽  
pp. 1503-1508 ◽  
Author(s):  
Jacob Bodilsen ◽  
Michael Dalager-Pedersen ◽  
Nicolai Kjærgaard ◽  
Diederik van de Beek ◽  
Matthijs C Brouwer ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Brain Abscess ◽  
Predictive Value ◽  
Patient Registry ◽  
National Patient Registry ◽  
Diagnosis Codes ◽  
Danish National Patient Registry ◽  
National Patient ◽  
Icd 10

scholarly journals Validating surgical procedure codes for inflammatory bowel disease in the Swedish National Patient Register

2019 ◽  
Author(s):  
Anders Forss ◽  
Pär Myrelid ◽  
Ola Olén ◽  
Åsa H Everhov ◽  
Caroline Nordenvall ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Sensitivity And Specificity ◽  
Bowel Disease ◽  
Surgical Procedure ◽  
High Sensitivity ◽  
National Patient Register ◽  
Patient Register ◽  
National Patient ◽  
Inflammatory Bowel ◽  
Procedure Codes

Abstract Validating surgical procedure codes for inflammatory bowel disease in the Swedish National Patient Register Background: About 50% of patients with Crohn’s disease (CD) and about 20% of those with ulcerative colitis (UC) undergo surgery at some point during the course of the disease. The diagnostic validity of the Swedish National Patient Register (NPR) has previously been shown to be high for inflammatory bowel disease (IBD), but there are little data on the validity of IBD-related surgical procedure codes. Methods: Using patient chart data as the gold standard, surgical procedure codes registered between 1966 and 2014 in the NPR were abstracted and validated in 262 patients with a medical diagnosis of IBD. Of these, 53 patients had reliable data about IBD-related surgery. The positive predictive value (PPV), sensitivity and specificity of the surgical procedure codes were calculated. Results: In total, 158 codes were registered in the NPR. 155 of these, representing 60 different surgical procedure codes, were also present in the patient charts and validated using a standardized form. Of the validated codes 153/155 were concordant against the patient charts, corresponding to a PPV of 96.8% (95%CI=93.9-99.1). Stratified in abdominal, perianal and other surgery, the corresponding PPVs were 94.1% (95%CI=88.7-98.6), 100% (95%CI=100-100) and 98.1% (95%CI=93.1-100), respectively. Of 164 surgical procedure codes in the validated patient charts, 155 were registered in the NPR, corresponding to a sensitivity of the surgical procedure codes of 94.5% (95%CI=89.6-99.3). The specificity of the NPR was 98.5% (95%CI=97.6-100). Conclusions: Data on IBD-related surgical procedure codes are reliable, with the Swedish National Patient Register showing a high sensitivity and specificity for such surgery. Keywords: Epidemiology, Inflammatory bowel disease, Validation, National Patient Register, Procedure code

scholarly journals Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study

2018 ◽  
Vol 146 (15) ◽  
pp. 1965-1967 ◽  
Author(s):  
Lauge Østergaard ◽  
Kasper Adelborg ◽  
Jens Sundbøll ◽  
Lars Pedersen ◽  
Emil Loldrup Fosbøl ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Medical Records ◽  
Electronic Device ◽  
Patient Registry ◽  
Cardiac Implantable Electronic Device ◽  
National Patient Registry ◽  
Danish National Patient Registry ◽  
National Patient

AbstractThe positive predictive value of an infective endocarditis diagnosis is approximately 80% in the Danish National Patient Registry. However, since infective endocarditis is a heterogeneous disease implying long-term intravenous treatment, we hypothesiszed that the positive predictive value varies by length of hospital stay. A total of 100 patients with first-time infective endocarditis in the Danish National Patient Registry were identified from January 2010 – December 2012 at the University hospital of Aarhus and regional hospitals of Herning and Randers. Medical records were reviewed. We calculated the positive predictive value according to admission length, and separately for patients with a cardiac implantable electronic device and a prosthetic heart valve using the Wilson score method. Among the 92 medical records available for review, the majority of the patients had admission length ⩾2 weeks. The positive predictive value increased with length of admission. In patients with admission length <2 weeks the positive predictive value was 65% while it was 90% for admission length ⩾2 weeks. The positive predictive value was 81% for patients with a cardiac implantable electronic device and 87% for patients with a prosthetic valve. The positive predictive value of the infective endocarditis diagnosis in the Danish National Patient Registry is high for patients with admission length ⩾2 weeks. Using this algorithm, the Danish National Patient Registry provides a valid source for identifying infective endocarditis for research.

scholarly journals Positive predictive value of acute and chronic pancreatitis diagnoses in the Danish National Patient Registry: A validation study

2018 ◽  
Vol 48 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Jakob Kirkegård ◽  
Marie R. Mortensen ◽  
Ida R. Johannsen ◽  
Frank V. Mortensen ◽  
Deirdre Cronin-Fenton
Keyword(s):  
Acute Pancreatitis ◽  
Chronic Pancreatitis ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Medical Records ◽  
Patient Registry ◽  
National Patient Registry ◽  
Danish National Patient Registry ◽  
National Patient ◽  
Acute And Chronic Pancreatitis

Aims: To examine the validity of the diagnoses of acute and chronic pancreatitis registered in the Danish National Patient Registry. Methods: We identified all patients in the Danish National Patient Registry admitted to two Danish hospitals with acute or chronic pancreatitis from 1996 to 2013. From this population, we randomly sampled 100 patients with acute pancreatitis and 100 patients with chronic pancreatitis. For each cohort, we computed the positive predictive values and associated 95% confidence intervals (CIs) for the discharge diagnosis of acute or chronic pancreatitis using medical records as the gold standard. Results: We identified 2617 patients with acute pancreatitis and 1284 patients with chronic pancreatitis discharged from either of the two hospitals during the study period. Of these, 776 (19.9%) had a diagnosis of both acute and chronic pancreatitis and are thus present in both cohorts. From the 200 sampled patients, a total of 138 (69.0%) medical records were available for review. The positive predictive value for a diagnosis of acute pancreatitis in the Danish National Patient Registry was 97.3% (95% CI 90.5–99.2%) and for chronic pancreatitis 83.1% (95% CI 72.2–90.3%). Conclusions: The validity of diagnoses of acute and chronic pancreatitis registered in the Danish National Patient Registry since 1996 is generally high.

scholarly journals Positive Predictive Value of the Giant Cell Arteritis Diagnosis in the Danish National Patient Registry: A Validation Study

2020 ◽  
Vol Volume 12 ◽  
pp. 731-736
Author(s):  
Peter Engholm Hjort ◽  
Philip Therkildsen ◽  
Berit Dalsgaard Nielsen ◽  
Ib Tønder Hansen ◽  
Mette Nørgaard ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Validation Study ◽  
Predictive Value ◽  
Patient Registry ◽  
National Patient Registry ◽  
Danish National Patient Registry ◽  
National Patient

scholarly journals Anti-Saccharomyces cerevisiae mannan antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease: prevalence and diagnostic role

Gut ◽  
1998 ◽  
Vol 42 (6) ◽  
pp. 788-791 ◽  
Author(s):  
J-F Quinton ◽  
B Sendid ◽  
D Reumaux ◽  
P Duthilleul ◽  
A Cortot ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Positive Predictive Value ◽  
Bowel Disease ◽  
Inflammatory Bowel ◽  
Sensitivity Specificity ◽  
Antineutrophil Cytoplasmic Autoantibodies

Background—Perinuclear antineutrophil cytoplasmic autoantibodies (pANCA) are a well recognised marker for ulcerative colitis. Antibodies to oligomannosidic epitopes of the yeastSaccharomyces cerevisiae (ASCA) are a new marker associated with Crohn’s disease.Aims—To assess the value of detecting pANCA and/or ASCA for the diagnosis of ulcerative colitis and Crohn’s disease.Methods—Serum samples were obtained from 100 patients with Crohn’s disease, 101 patients with ulcerative colitis, 27 patients with other miscellaneous diarrhoeal illnesses, and 163 healthy controls. Determination of pANCA and ASCA was performed using the standardised indirect immunofluorescence technique and an ELISA, respectively.Results—The combination of a positive pANCA test and a negative ASCA test yielded a sensitivity, specificity, and positive predictive value of 57%, 97%, and 92.5% respectively for ulcerative colitis. The combination of a positive ASCA test and a negative pANCA test yielded a sensitivity, specificity, and positive predictive value of 49%, 97%, and 96% respectively for Crohn’s disease. Among patients with miscellaneous non-inflammatory bowel disorders, three were ASCA positive and two were pANCA positive. One control was ASCA positive. The presence of ASCA in patients with Crohn’s disease was associated with small bowel involvement.Conclusion—ASCA and pANCA are strongly associated with Crohn’s disease and ulcerative colitis, respectively. Combination of both tests could help the diagnosis of inflammatory bowel disease.

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