scholarly journals Evaluating associations between the benefits and risks of drug therapy in type 2 diabetes: a joint modeling approach

2018 ◽  
Vol Volume 10 ◽  
pp. 1869-1877 ◽  
Author(s):  
John M. Dennis ◽  
Beverley M. Shields ◽  
Angus G. Jones ◽  
Ewan R. Pearson ◽  
Andrew T. Hattersley ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Drug Therapy ◽  
Joint Modeling ◽  
Modeling Approach

scholarly journals Effect of Trajectories of Glycemic Control on Mortality in Type 2 Diabetes: A Semiparametric Joint Modeling Approach

2010 ◽  
Vol 171 (10) ◽  
pp. 1090-1098 ◽  
Author(s):  
M. Gebregziabher ◽  
L. E. Egede ◽  
C. P. Lynch ◽  
C. Echols ◽  
Y. Zhao
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Joint Modeling ◽  
Modeling Approach

scholarly journals Health Economic Evaluation of Type 2 Diabetes Mellitus: A Clinical Practice Focused Review

2015 ◽  
Vol 8 ◽  
pp. CMED.S20906 ◽  
Author(s):  
Andreas Liebl ◽  
Kamlesh Khunti ◽  
Domingo Orozco-Beltran ◽  
Jean-Francois Yale
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Health Economic ◽  
Type 2 Diabetes Mellitus ◽  
Drug Therapy ◽  
Glycemic Control ◽  
Cost Effective ◽  
Treatment Intensification ◽  
Total Cost

Type 2 diabetes mellitus (T2D) is a growing healthcare burden primarily due to long-term complications. Strict glycemic control helps in preventing complications, and early introduction of insulin may be more cost-effective than maintaining patients on multiple oral agents. This is an expert opinion review based on English peer-reviewed articles (2000–2012) to discuss the health economic consequences of T2D treatment intensification. T2D costs are driven by inpatient care for treatment of diabetes complications (40%–60% of total cost), with drug therapy for glycemic control representing 18% of the total cost. Insulin therapy provides the most improved glycemic control and reduction of complications, although hypoglycemia and weight gain may occur. Early treatment intensification with insulin analogs in patients with poor glycemic control appears to be cost-effective and improves clinical outcomes. Key Messages • Type 2 diabetes mellitus is a growing burden on healthcare services. • Despite the high cost of drug therapy versus diet and lifestyle interventions, treatment intensification with insulin analog therapy is a cost-effective strategy for improving clinical outcomes in patients with poor glycemic control.

scholarly journals Primary Care Detection of Chronic Kidney Disease in Adults with Type-2 Diabetes: The ADD-CKD Study (Awareness, Detection and Drug Therapy in Type 2 Diabetes and Chronic Kidney Disease)

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e110535 ◽  
Author(s):  
Lynda A. Szczech ◽  
Rebecca C. Stewart ◽  
Hsu-Lin Su ◽  
Richard J. DeLoskey ◽  
Brad C. Astor ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Primary Care ◽  
Chronic Kidney Disease ◽  
Drug Therapy ◽  
Kidney Disease

scholarly journals Forecasting the burden of type 2 diabetes mellitus in Qatar to 2050: A novel modeling approach

2018 ◽  
Vol 137 ◽  
pp. 100-108 ◽  
Author(s):  
Susanne F. Awad ◽  
Martin O'Flaherty ◽  
Julia Critchley ◽  
Laith J. Abu-Raddad
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Modeling Approach
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