scholarly journals Patients undergoing long-term treatment with antihypertensive eye drops responded positively with respect to their ocular surface disorder to oral supplementation with antioxidants and essential fatty acids

2013 ◽  
pp. 711 ◽  
Author(s):  
Maria Pinazo-duran ◽  
Jorge Cantu-Dibildox ◽  
Carmen Galbis-Estrada ◽  
Carla Marco-Ramirez ◽  
Manuel Diaz-Llopis ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Ocular Surface ◽  
Essential Fatty Acids ◽  
Term Treatment ◽  
Eye Drops ◽  
Oral Supplementation ◽  
Long Term Treatment ◽  
Surface Disorder ◽  
Ocular Surface Disorder

Ocular Surface Alteration after Long-term Treatment with an Antiglaucomatous Drug

Ophthalmology ◽  
1992 ◽  
Vol 99 (7) ◽  
pp. 1082-1088 ◽  
Author(s):  
José M. Herreras ◽  
J. Carlos Pastor ◽  
Margarita Calonge ◽  
Victor M. Asensio
Keyword(s):  
Ocular Surface ◽  
Term Treatment ◽  
Long Term Treatment ◽  
Surface Alteration

scholarly journals Effect of an oral dietary supplementation by a formulation based on silibinin-phosphatidylcholine complex in cats with liver diseases

2017 ◽  
Author(s):  
Elena Biasibetti ◽  
Tiziana Cocca ◽  
Maria Teresa Capucchio ◽  
Stefano Togni ◽  
Luca Giacomelli ◽  
...  
Keyword(s):  
Liver Diseases ◽  
Total Bilirubin ◽  
Liver Enzymes ◽  
Dietary Supplementation ◽  
Term Treatment ◽  
Hepatic Lipidosis ◽  
Oral Supplementation ◽  
Long Term Treatment ◽  
Glutamyl Transferase

Background: Liver pathology in cats represents a frequent clinical condition occurring in animals of any age. Dietary supplementation with hepatoprotective and antioxidant products could represent a beneficial strategy to prevent and treat these disorders. We evaluated the tolerability and efficacy of long-term treatment with a multi-component, dietary supplement containing functional natural ingredients with recognized hepatoprotective properties in cats suffering from liver diseases Methods: 20 European domestic cats of either gender, 10 with hepatic lipidosis and 10 with cholangitis received for 180 consecutive days a multi-component formulation based on the silibinin-phosphatidylcholine complex as paste or tablet. Clinical assessment and blood and urine parameters were evaluated at T0 (inclusion time) and after 7, 28, 60, 90 and 180 days from the initiation of the study. Results: The oral supplementation with the silibinin-phosphatidylcholine complex significantly reduced the activity of liver enzymes in serum (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, γ -glutamyl transferase) and the content of total bilirubin, albumin, pre- and post- bile acids, in cats with hepatic lipidosis or cholangitis, normalizing their liver function parameters. Moreover, following the supplementation, the appetite was restored in all cats and the frequent episodes of diarrhea and vomit reported at inclusion almost disappeared. Discussion: Dietary supplementation with the silibinin-phosphatidylcholine complex containing functional natural ingredients with recognized hepatoprotective and antioxidant actions might represent an effective strategy to improve the conditions of liver dysfunction, such as hepatitis lipidosis and cholangitis, in cats.

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