scholarly journals Drugs Dosing in Geriatric Patients Depending on Kidney Function Estimated by MDRD and Cockroft-Gault Formulas

2021 ◽  
Vol Volume 16 ◽  
pp. 2057-2067
Author(s):  
Małgorzata Szymala-Pędzik ◽  
Joanna Żórawska ◽  
Jacek Ciach
Keyword(s):  
Kidney Function ◽  
Geriatric Patients

scholarly journals Kidney function and clinical recommendations of drug dose adjustment in geriatric patients

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Marlies Karsch-Völk ◽  
Elisa Schmid ◽  
Stefan Wagenpfeil ◽  
Klaus Linde ◽  
Uwe Heemann ◽  
...  
Keyword(s):  
Kidney Function ◽  
Dose Adjustment ◽  
Geriatric Patients ◽  
Drug Dose ◽  
Clinical Recommendations ◽  
Drug Dose Adjustment

scholarly journals MO358ACUTE KIDNEY INJURY AND MORTALITY RISK IN OLDER ADULTS WITH AND WITHOUT COVID-19: DATA FROM GEROCOVID STUDY

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Hong Xu ◽  
Sara Garcia-Ptacek ◽  
Martin Annetorp ◽  
Annette Bruchfeld ◽  
Tommy Cederholm ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Kidney Function ◽  
Geriatric Patients ◽  
Vital Signs ◽  
Kidney Injury ◽  
Adverse Outcomes ◽  
Hospital Death ◽  
The Difference ◽  
Hospitalized Older Adults

Abstract Background and Aims Research regarding COVID-19 and acute kidney injury (AKI) in older adults is scarce. We evaluated the risk factors and outcomes of AKI in hospitalized older adults with and without COVID-19. Method Observational study of patients admitted to two geriatric clinics in the Stockholm Region of Sweden during the first wave of the COVID-19 pandemic from March 1st to June 15th 2020. The difference in incidence, risk factors and adverse outcomes for AKI between patients with or without COVID-19 were examined. Odds ratios (ORs) for AKI were obtained from logistic regressions. The hazard ratios (HRs) for the risk of in-hospital death were calculated from Cox proportional hazard regression models. Results We analyzed 316 older patients hospitalized for COVID-19 and 876 patients for non-COVID-19 diagnoses. The mean age was 83±9 years, 57% were women, and mean baseline kidney function as depicted by estimated glomerular filtration rate (eGFR) was 62±23 ml/min/1.73m2. AKI occurred in 92 (29%) of patients with COVID-19 vs. 159 (18%) without COVID-19. The severity of AKI was significantly worse in patients with COVID-19 compared with non-COVID patients. The odds for developing AKI were higher in patients with COVID-19 (adjusted OR, 1.70; 95% CI, 1.04-2.76), low baseline kidney function [4.19 (2.48-7.05), for eGFR 30 ∼ <60 ml/min/1.73m2, and 20.3 (9.95-41.3) for eGFR <30ml/min/1.73m2], and higher C-reactive protein (CRP) level (OR 1.81(1.11-2.95)). The risk of in-hospital death was highest in patients with COVID-19 and AKI [adjusted HR 23.5, 95% CI (8.75-63.0)], followed by COVID-19 without AKI [9.10 (3.52-23.6)] and by patients without COVID-19 and with AKI [6.38 (2.28-17.9)] after adjusting for patient demographics, vital signs, baseline kidney function and medications and using non-COVID patients with no AKI as reference. Conclusion Geriatric patients hospitalized with COVID-19 had a higher incidence of AKI compared with patients hospitalized with other diagnoses. AKI and COVID-19 were associated with in-hospital death. Optimal management of AKI may improve the outcome of COVID-19 in geriatric patients.

Aging and Autism

2012 ◽  
Vol 17 (2) ◽  
pp. 69-75 ◽  
Author(s):  
Pamela A. Smith
Keyword(s):  
Health Care ◽  
Autism Spectrum Disorders ◽  
Patient Group ◽  
Older Patients ◽  
Geriatric Patients ◽  
Recent Literature ◽  
Communication Disorders ◽  
Autism Spectrum ◽  
Need For Support ◽  
Spectrum Disorders

In this article, I will review the available recent literature about the aging population with autism, a patient group that researchers know little about and a group that is experiencing a growing need for support from communication disorders professionals. Speech-language pathologists working with geriatric patients should become familiar with this issue, as the numbers of older patients with autism spectrum disorders is likely to increase. Our profession and our health care system must prepare to meet the challenge these patients and residents will present as they age.

Responding to Clinicians' Challenges in Working With Geriatric Patients

2011 ◽  
Vol 16 (1) ◽  
pp. 22-29
Author(s):  
Lisa Y. Milliken ◽  
Dawn Ralph ◽  
Sally Jones-McNamara
Keyword(s):  
Health Care ◽  
Geriatric Patients ◽  
Clinical Scenario ◽  
Medical Diagnoses ◽  
Communication Deficits ◽  
Resident Care ◽  
Physical Limitations

Clinicians work with older residents who have not only multiple physical limitations, but cognitive loss, communication deficits, dysphagia, and multiple medical diagnoses. They must work within procedural, regulatory, and reimbursement systems that challenge them to provide optimal resident care. In this article, the authors will discuss some specific challenges brought forth by clinicians in response to a clinical scenario and will provide information and feedback from several health-care consultants.

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