scholarly journals Fat infiltration in the gluteus minimus muscle in older adults

2018 ◽  
Vol Volume 13 ◽  
pp. 1011-1017 ◽  
Author(s):  
Yuta Takano ◽  
Hiroto Kobayashi ◽  
Takuma Yuri ◽  
Saori Yoshida ◽  
Akira Naito ◽  
...  
Keyword(s):  
Older Adults ◽  
Fat Infiltration ◽  
Gluteus Minimus ◽  
Gluteus Minimus Muscle

scholarly journals Plasma Metabolites Associated with Muscle Fat Infiltration in Community-Dwelling Older Adults from the Health ABC Study

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 22-22
Author(s):  
Samaneh Farsijan ◽  
Megan Marron ◽  
Iva Miljkovic ◽  
Mary Baugh ◽  
Stephen Kritchevsky ◽  
...  
Keyword(s):  
Older Adults ◽  
Organic Acids ◽  
African American Men ◽  
Older Men ◽  
Community Dwelling ◽  
Metabolic Phenotype ◽  
Plasma Metabolites ◽  
Muscle Area ◽  
Fat Infiltration ◽  
Fat Depots

Abstract Objectives Age-related increase in muscle fat depots, i.e., myosteatosis, is a contributing factor to muscular dysfunction in older adults leading to frailty and disability. Myosteatosis is a complex condition that is associated with aging and diverse pathologies, including cancer and diabetes. We have previously shown that the relationship between muscle fat deposition and reduced physical function is moderated by muscle area and it is only observed in individuals with high muscle area. A further characterization of the metabolic phenotype associated with myoseatosis may shed light on the underlying biological mechanisms involved in its pathophysiology. Thus, we sought to further explore the heterogeneity of myosteatosis using a semi-targeted metabolomics approach to determine the plasma metabolites associated with myosteatosis in community-dwelling older men. Methods We performed a cross-sectional analysis of 314 African-American men (age: 69–79 years) from the Health ABC study at baseline. Mid-thigh inter-muscular fat (IMF) area by CT and 350 plasma metabolites by liquid-chromatography/mass spectrometry were measured. Partial correlation analysis was performed to determine metabolites associated with IMF. Results 161 metabolites were correlated with IMF (P < 0.05). After adjustment for age, weight, physical activity, medications and smoking, 36 metabolites remained significant with a false discovery rate of ≤0.25 to correct for multiple comparisons. Majority of IMF-associated metabolites were lipids/lipid-like molecules (26/36), followed by organic acids, including amino acids (5/36). Among these metabolites, only glutamine (from organic-acids) and mevalonic acid, (from fatty acids) were negatively correlated with IMF, while the remaining 34 metabolites were positively correlated. Notably, metabolic profiles of participants were distinctly different across different levels of myosteatosis, categorized by quartiles of IMF. Conclusions Dysregulated lipid and amino acid metabolism was a metabolomic hallmark of myosteatosis in this cohort of older men. Further exploration of metabolic heterogeneity of myosteatosis may help better understand the significance of fat infiltration on muscle health in aging. Funding Sources NIH/National Institute of Aging & NIA T32-AG0001810.

scholarly journals Fat Infiltration of Muscle, Diabetes, and Clinical Fracture Risk in Older Adults

2010 ◽  
Vol 95 (11) ◽  
pp. E368-E372 ◽  
Author(s):  
Anne L. Schafer ◽  
Eric Vittinghoff ◽  
Thomas F. Lang ◽  
Deborah E. Sellmeyer ◽  
Tamara B. Harris ◽  
...  
Keyword(s):  
Older Adults ◽  
Fracture Risk ◽  
Fat Infiltration ◽  
Clinical Fracture

scholarly journals Sarcopenia, Ectopic Fat Infiltration into the Lumbar Paravertebral Muscles, and Lumbo-Pelvic Deformity in Older Adults Undergoing Lumbar Surgery

Spine ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Deokcheol Lee ◽  
Tomofumi Kuroki ◽  
Takuya Nagai ◽  
Keisuke Kawano ◽  
Kiyoshi Higa ◽  
...  
Keyword(s):  
Older Adults ◽  
Ectopic Fat ◽  
Lumbar Surgery ◽  
Fat Infiltration ◽  
Paravertebral Muscles

scholarly journals Validation and Test-Retest Reliability of New Thermographic Technique Called Thermovision Technique of Dry Needling for Gluteus Minimus Trigger Points in Sciatica Subjects and TrPs-Negative Healthy Volunteers

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Elżbieta Skorupska ◽  
Michał Rychlik ◽  
Włodzimierz Samborski
Keyword(s):  
Healthy Volunteers ◽  
Diagnostic Criteria ◽  
Trigger Points ◽  
Referred Pain ◽  
Maximum Temperature ◽  
Dry Needling ◽  
Retest Reliability ◽  
Gluteus Minimus ◽  
Test Retest Reliability ◽  
Gluteus Minimus Muscle

The aim of this study was to assess the validity and test-retest reliability of Thermovision Technique of Dry Needling (TTDN) for the gluteus minimus muscle. TTDN is a new thermography approach used to support trigger points (TrPs) diagnostic criteria by presence of short-term vasomotor reactions occurring in the area where TrPs refer pain.Method. Thirty chronic sciatica patients (n=15TrP-positive andn=15TrPs-negative) and 15 healthy volunteers were evaluated by TTDN three times during two consecutive days based on TrPs of the gluteus minimus muscle confirmed additionally by referred pain presence. TTDN employs average temperature (Tavr), maximum temperature (Tmax), low/high isothermal-area, and autonomic referred pain phenomenon (AURP) that reflects vasodilatation/vasoconstriction. Validity and test-retest reliability were assessed concurrently.Results. Two components of TTDN validity and reliability,Tavrand AURP, had almost perfect agreement according toκ(e.g., thigh: 0.880 and 0.938; calf: 0.902 and 0.956, resp.). The sensitivity forTavr,Tmax, AURP, and high isothermal-area was 100% for everyone, but specificity of 100% was forTavrand AURP only.Conclusion. TTDN is a valid and reliable method forTavrand AURP measurement to support TrPs diagnostic criteria for the gluteus minimus muscle when digitally evoked referred pain pattern is present.

scholarly journals Impact of Weight Loss on Physical Function with Changes in Strength, Muscle Mass, and Muscle Fat Infiltration in Overweight to Moderately Obese Older Adults: A Randomized Clinical Trial

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Adam J. Santanasto ◽  
Nancy W. Glynn ◽  
Mark A. Newman ◽  
Christopher A. Taylor ◽  
Maria Mori Brooks ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Weight Loss ◽  
Physical Function ◽  
Muscle Mass ◽  
Successful Aging ◽  
Knee Extensor ◽  
Muscle Area ◽  
Fat Infiltration ◽  
Muscle Fat Infiltration

Purpose. Evaluate the effects of weight loss on muscle mass and area, muscle fat infiltration, strength, and their association with physical function.Methods. Thirty-six overweight to moderately obese, sedentary older adults were randomized into either a physical activity plus weight loss (PA+WL) or physical activity plus successful aging health education (PA+SA) program. Measurements included body composition by dual-energy X-ray absorptiometry, computerized tomography, knee extensor strength, and short physical performance battery (SPPB).Results. At 6 months, PA+WL lost greater thigh fat and muscle area compared to PA+SA. PA+WL lost 12.4% strength; PA+SA lost 1.0%. Muscle fat infiltration decreased significantly in PA+WL and PA+SA. Thigh fat area decreased 6-fold in comparison to lean area in PA+WL. Change in total SPPB score was strongly inversely correlated with change in fat but not with change in lean or strength.Conclusion. Weight loss resulted in additional improvements in function over exercise alone, primarily due to loss of body fat.

scholarly journals Analysis of Gluteus Minimus Muscle Activity during Single Leg Stance on Unstable Surfaces

2019 ◽  
Vol 34 (6) ◽  
pp. 731-734
Author(s):  
Yusuke MUROFUSHI ◽  
Teruhiko KAWAKAMI ◽  
Hazime ITO
Keyword(s):  
Muscle Activity ◽  
Gluteus Minimus ◽  
Single Leg Stance ◽  
Gluteus Minimus Muscle
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