scholarly journals Medication regimen complexity in ambulatory older adults with heart failure

2017 ◽  
Vol Volume 12 ◽  
pp. 679-686 ◽  
Author(s):  
Michael Cobretti ◽  
Robert Page II ◽  
Sunny Linnebur ◽  
Kimberly Deininger ◽  
Amrut Ambardekar ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

scholarly journals Medication Regimen Complexity in Older Adults with Heart Failure

2016 ◽  
Vol 35 (4) ◽  
pp. S419-S420
Author(s):  
M.R. Cobretti ◽  
K.M. Deininger ◽  
S.A. Linnebur ◽  
R.L. Page ◽  
J. Lindenfeld ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

scholarly journals Medication-Related Factors and Hospital Readmission in Older Adults with Chronic Kidney Disease

2019 ◽  
Vol 8 (3) ◽  
pp. 395 ◽  
Author(s):  
Wubshet H. Tesfaye ◽  
Gregory M. Peterson ◽  
Ronald L. Castelino ◽  
Charlotte McKercher ◽  
Matthew Jose ◽  
...  
Keyword(s):  
Older Adults ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Hospital Readmission ◽  
Hospital Readmissions ◽  
Medication Regimen ◽  
Related Factors ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Medication Appropriateness

This study aimed to examine the association between medication-related factors and risk of hospital readmission in older patients with chronic kidney disease (CKD). A retrospective analysis was conducted targeting older CKD (n = 204) patients admitted to an Australian hospital. Medication appropriateness (Medication Appropriateness Index; MAI), medication regimen complexity (number of medications and Medication Regimen Complexity Index; MRCI) and use of selected medication classes were exposure variables. Outcomes were occurrence of readmission within 30 and 90 days, and time to readmission within 90 days. Logistic and Cox hazards regression were used to identify factors associated with readmission. Overall, 50 patients (24%) were readmitted within 30 days, while 81 (40%) were readmitted within 90 days. Mean time to readmission within 90 days was 66 (SD 34) days. Medication appropriateness and regimen complexity were not independently associated with 30- or 90-day hospital readmissions in older adults with CKD, whereas use of renin‒angiotensin blockers was associated with reduced occurrence of 30-day (adjusted OR 0.39; 95% CI 0.19–0.79) and 90-day readmissions (adjusted OR 0.45; 95% CI 0.24–0.84) and longer time to readmission within 90 days (adjusted HR 0.52; 95% CI 0.33–0.83). This finding highlights the importance of considering the potential benefits of individual medications during medication review in older CKD patients.

Correlation between medication regimen complexity and quality of life in patients with heart failure

2020 ◽  
Vol 16 (10) ◽  
pp. 1498-1501 ◽  
Author(s):  
G. Lucy Wilkening ◽  
Sonja Brune ◽  
Pablo F. Saenz ◽  
Lourdes M. Vega ◽  
Bethany A. Kalich
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Patients With Heart Failure ◽  
Regimen Complexity

scholarly journals Medication regimen complexity and readmissions after hospitalization for heart failure, acute myocardial infarction, pneumonia, and chronic obstructive pulmonary disease

2016 ◽  
Vol 4 ◽  
pp. 205031211663242 ◽  
Author(s):  
Nada Abou-Karam ◽  
Chad Bradford ◽  
Kajua B Lor ◽  
Mitchell Barnett ◽  
Michelle Ha ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Chronic Obstructive Pulmonary Disease ◽  
Acute Myocardial Infarction ◽  
Chronic Obstructive ◽  
Medication Regimen ◽  
Obstructive Pulmonary Disease ◽  
Medication Regimen Complexity ◽  
Complexity Index ◽  
Regimen Complexity

Objectives: Readmission rate is increasingly being viewed as a key indicator of health system performance. Medication regimen complexity index scores may be predictive of readmissions; however, few studies have examined this potential association. The primary objective of this study was to determine whether medication regimen complexity index is associated with all-cause 30-day readmission after admission for heart failure, acute myocardial infarction, pneumonia, or chronic obstructive pulmonary disease. Methods: This study was an institutional review board–approved, multi-center, case–control study. Patients admitted with a primary diagnosis of heart failure, acute myocardial infarction, pneumonia, or chronic obstructive pulmonary disease were randomly selected for inclusion. Patients were excluded if they discharged against medical advice or expired during their index visit. Block randomization was utilized for equal representation of index diagnosis and site. Discharge medication regimen complexity index scores were compared between subjects with readmission versus those without. Medication regimen complexity index score was then used as a predictor in logistic regression modeling for readmission. Results: Seven hundred and fifty-six patients were randomly selected for inclusion, and 101 (13.4%) readmitted within 30 days. The readmission group had higher medication regimen complexity index scores than the no-readmission group ( p < 0.01). However, after controlling for demographics, disease state, length of stay, site, and medication count, medication regimen complexity index was no longer a significant predictor of readmission (odds ratio 0.99, 95% confidence interval 0.97–1.01) or revisit (odds ratio 0.99, 95% confidence interval 0.98–1.02). Conclusion: There is little evidence to support the use of medication regimen complexity index in readmission prediction when other measures are available. Medication regimen complexity index may lack sufficient sensitivity to capture an effect of medication regimen complexity on all-cause readmission.

Validation and standardization of the Brazilian version of the Medication Regimen Complexity Index for older adults in primary care

2018 ◽  
Vol 18 (6) ◽  
pp. 853-859 ◽  
Author(s):  
Laís LN Pantuzza ◽  
Maria das Graças B Ceccato ◽  
Micheline R Silveira ◽  
Isabela VL Pinto ◽  
Adriano Max M Reis
Keyword(s):  
Older Adults ◽  
Primary Care ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Complexity Index ◽  
Brazilian Version ◽  
Regimen Complexity

Factors associated with high medication regimen complexity in primary care older adults in Brazil

2019 ◽  
Vol 11 (2) ◽  
pp. 279-287 ◽  
Author(s):  
Laís Lessa Neiva Pantuzza ◽  
Maria das Graças Braga Ceccato ◽  
Edna Afonso Reis ◽  
Micheline Rosa Silveira ◽  
Celline Cardoso Almeida-Brasil ◽  
...  
Keyword(s):  
Older Adults ◽  
Primary Care ◽  
Medication Regimen ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

Patient-level Medication Regimen Complexity in Older Adults With Depression

2014 ◽  
Vol 36 (11) ◽  
pp. 1538-1546.e1 ◽  
Author(s):  
Sunny A. Linnebur ◽  
Joseph P. Vande Griend ◽  
Kelli R. Metz ◽  
Patrick W. Hosokawa ◽  
Jan D. Hirsch ◽  
...  
Keyword(s):  
Older Adults ◽  
Medication Regimen ◽  
Patient Level ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

scholarly journals A Cross-Sectional Assessment of Urinary Tract Infections Among Geriatric Patients: Prevalence, Medication Regimen Complexity, and Factors Associated With Treatment Outcomes

2021 ◽  
Vol 9 ◽  
Author(s):  
Ali Akhtar ◽  
Mohamed Azmi Ahmad Hassali ◽  
Hadzliana Zainal ◽  
Irfhan Ali ◽  
Amer Hayat Khan
Keyword(s):  
Older Adults ◽  
Urinary Tract ◽  
Treatment Outcomes ◽  
Medication Regimen ◽  
Cross Sectional ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Study Population ◽  
Tract Infections

Background: Urinary tract infections (UTIs) are the second most prevalent infection among the elderly population. Hence, the current study aimed to evaluate the prevalence of UTIs among older adults, medication regimen complexity, and the factors associated with the treatment outcomes of elderly patients infected with UTIs.Methods: A retrospective cross-sectional study was conducted at the Department of Urology, Hospital Pulau Pinang, Malaysia. The patients ≥65 years of age were included in the present study with a confirmed diagnosis of UTIs from 2014 to 2018 (5 years).Results: A total of 460 patients met the inclusion criteria and were included in the present study. Cystitis (37.6%) was the most prevalent UTI among the study population followed by asymptomatic bacteriuria (ASB) (31.9%), pyelonephritis (13.9%), urosepsis (10.2%), and prostatitis (6.4%). Unasyn (ampicillin and sulbactam) was used to treat the UTIs followed by Bactrim (trimethoprim/sulfamethoxazole), and ciprofloxacin. The factors associated with the treatment outcomes of UTIs were gender (odd ratio [OR] = 1.628; p = 0.018), polypharmacy (OR = 0.647; p = 0.033), and presence of other comorbidities (OR = 2.004; p = 0.002) among the study population.Conclusion: Cystitis is the most common UTI observed in older adults. Gender, the burden of polypharmacy, and the presence of comorbidities are the factors that directly affect the treatment outcomes of UTIs among the study population.

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