scholarly journals Antiretroviral treatment switch strategies for lowering the costs of antiretroviral therapy in subjects with suppressed HIV-1 viremia in Spain

2013 ◽  
pp. 215 ◽  
Author(s):  
Josep Llibre ◽  
Gloria Cardona ◽  
Santos ◽  
Angels Andreu ◽  
Josep O. Estrada ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Antiretroviral Treatment ◽  
Treatment Switch ◽  
Hiv 1

scholarly journals Antiretroviral Therapy-Induced Functional Modification of IgG4 and IgM Responses in HIV-1–Infected Individuals Screened by an Allosteric Biosensor

2008 ◽  
Vol 13 (8) ◽  
pp. 817-821 ◽  
Author(s):  
Rosa María Ferraz ◽  
Miguel Angel Martínez ◽  
Rafael Cubarsi ◽  
Antonio Villaverde
Keyword(s):  
Antiretroviral Therapy ◽  
Structural Modification ◽  
Antiretroviral Treatment ◽  
Humoral Response ◽  
Antiretroviral Drugs ◽  
Functional Adaptation ◽  
Antiviral Immune Response ◽  
Immunodeficiency Virus ◽  
Target Epitope ◽  
Hiv 1

We have explored the effect of antiretroviral drugs on the antiviral immune response in human immunodeficiency virus-1 (HIV-1)—infected patients by using an enzymatic immunosensor that detects epitope-modifying anti-gp41 antibodies. By this molecular sensing approach, we have identified an irreversible impact of drug administration on the functionality of IgG4 and IgM specific antibodies regarding the structural modification promoted on their target epitope. During the antiretroviral therapy, the prevalent induced fit promoted by IgM on the epitope was lost at the expense of that promoted by IgG4, suggesting alternative-ness in the neutralization potency of these antibody subpopulations. Because the particular drug composition of the antiretroviral treatment did not affect such immune shift, the obtained data strongly suggest that the drop in the viral load and the consequent lost of antigenemia are responsible for the functional adaptation observed in the humoral response. ( Journal of Biomolecular Screening 2008:817-821)

scholarly journals Viral and inflammatory markers in cerebrospinal fluid of patients with HIV-1-associated neurocognitive impairment during antiretroviral treatment switch

HIV Medicine ◽  
2015 ◽  
Vol 16 (6) ◽  
pp. 388-392 ◽  
Author(s):  
JM Tiraboschi ◽  
JA Muñoz-Moreno ◽  
MC Puertas ◽  
C Alonso-Villaverde ◽  
A Prats ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Inflammatory Markers ◽  
Antiretroviral Treatment ◽  
Neurocognitive Impairment ◽  
Treatment Switch ◽  
Hiv 1

HIV-1 superinfection in a patient with known HIV-2 – A case report

2020 ◽  
Vol 31 (3) ◽  
pp. 271-273
Author(s):  
Kyle Ring ◽  
David Muir ◽  
Nicola Mackie ◽  
Angela C Bailey
Keyword(s):  
Case Report ◽  
Antiretroviral Therapy ◽  
Protective Effect ◽  
Antiretroviral Treatment ◽  
Treatment Decisions ◽  
National Guidelines ◽  
Hiv 1

We report a case of HIV-1 superinfection in a patient with established HIV-2 infection. The patient was not taking antiretroviral therapy, in line with criteria in national guidelines, and reported no risk for infection with HIV-1. This case serves as a reminder that patients infected with HIV-2 remain susceptible to HIV-1 infection. The protective effect of antiretroviral treatment against HIV-1 infection should be a consideration in treatment decisions for individuals with HIV-2 infection.

scholarly journals Detection of Antiretroviral treatment failure among adult HIV-1 patients on anti-retroviral therapy for 12 +/- 3 months attending different Voluntary Counseling Testing and treatment centers in Khartoum state, Sudan

2020 ◽  
Author(s):  
Nafisa Ahmed Ibrahim ◽  
Khalid A Enan ◽  
Mahdi Mustafa Yagoup ◽  
Wafa Ibrahim Elhag
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Treatment Failure ◽  
Antiretroviral Treatment ◽  
Clinical Staging ◽  
Age Group ◽  
First Line ◽  
Voluntary Counseling ◽  
Hiv 1 ◽  
Antiretroviral Treatment Failure

Abstract Objective: Small number of people on antiretroviral therapy and their virological status in Sudan is lacking. This study aimed to determine the viral load for adult HIV-1 patients who were on antiretroviral therapy for 12+/- 3 months attending different Voluntary Counseling Testing and treatment centers (VCT/ART) in Khartoum state, Sudan.Results: out of 112 adult HIV-1 patients included in this study, only 17.9% (20/112) showed unsuppressed viral load (treatment failure). The majority of them from Omdurman VCT/ART center 80% (16/20), followed by Khartoum VCT/ART center 15% (3/20), Bahri VCT/ART center 5% (1/20) and non from Elban Gadeid VCT/ART center. All of them were on the first line of treatment. Most of them 30% (6/20) on 39-48 years old age group, the majority of them 55%(11/20) on stage 3 WHO clinical staging.

Novelties in evaluation and monitoring of HIV-1 infection: Is standard virological suppression enough for measuring antiretroviral treatment success?

Aids Reviews ◽  
2017 ◽  
Vol 19 (4) ◽  
Author(s):  
Valentina Svicher ◽  
Giulia Marchetti ◽  
Adrianna Ammassari ◽  
Francesca Ceccherini-Silberstein ◽  
Loredana Sarmati ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Treatment Success ◽  
Virological Suppression ◽  
Evaluation And Monitoring ◽  
Hiv 1
Sign in / Sign up

Export Citation Format

Share Document