scholarly journals Diagnostic indicators for peptic ulcer perforation at a tertiary care hospital in Thailand

2011 ◽  
pp. 283 ◽  
Author(s):  
Chutikarn Suriya ◽  
Nongyao Kasatpibal ◽  
Kunaviktikul ◽  
Kayee
Keyword(s):  
Peptic Ulcer ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Peptic Ulcer Perforation ◽  
Care Hospital ◽  
Ulcer Perforation

scholarly journals A clinical study of factors affecting the prognosis in duodenal ulcer perforation cases in tertiary care hospital, Kanchipuram district

2019 ◽  
Vol 6 (12) ◽  
pp. 4290
Author(s):  
Dhinesh Babu K. ◽  
M. Bhaskar
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Tertiary Care ◽  
Peptic Ulcer Perforation ◽  
Care Hospital ◽  
Chronic Alcoholic ◽  
Factors Affecting ◽  
Ulcer Disease ◽  
Ulcer Perforation ◽  
Duodenal Ulcer Perforation

Background: Peptic ulcer disease is an erosion of the lining of the stomach or duodenum. It is associated with potentially life-threatening complications such as bleeding, perforation and obstruction. The main predisposing factors for peptic ulcer perforation are smoking, use of non-steroidal anti-inflammatory drugs (NSAIDs), chronic stress, Helicobacter pylori infection, and age >60 years. In recent years, with introduction of proton pump inhibitors and increased knowledge of duodenal ulcer perforation (DUP) has decreased the incidence of DUP.Methods: 50 patients with DUP were studied prospectively with respect to age, gender, use of NSAIDs, morbidity, mortality and complications.Results: Out of 50 patients, the mean age of incidence DUP was 46 yrs, which is more common in males. And also 48% patients were chronic alcoholic and 52% patients were chronic smokers. Moreover, 14% patients were chronic NSAIDs users.Conclusions: Factors such as age, gender, use of NSAID, Alcohol and smoking affects the life expectancy of the patients, which leads to morbidity and mortality.

scholarly journals H. pylori and peptic ulcer perforation: prevalence of infection and role in surgical outcome

2021 ◽  
Vol 8 (4) ◽  
pp. 1243
Author(s):  
Saad Anwar ◽  
Afzal Anees ◽  
Nishat Afroz ◽  
Sabiha Aziz
Keyword(s):  
Peptic Ulcer ◽  
Surgical Outcome ◽  
Perforated Peptic Ulcer ◽  
Rapid Urease Test ◽  
Peptic Ulcer Perforation ◽  
Care Hospital ◽  
Ulcer Perforation ◽  
Test Kit ◽  
Urease Test ◽  
H Pylori

Background: Perforated peptic ulcer is one of the most common surgical emergencies. Despite a definite association of H. pylori with peptic ulcer disease, its association with peptic ulcer perforation is still doubtful. The aim of the present study was to know the prevalence of H. pylori infection and its role in surgical outcome of patients.Methods: This prospective observational study was carried out at a tertiary care hospital of north India for a period of two years and included 136 consecutive patients of perforated peptic ulcer who underwent emergency laparotomy. H. pylori infection was tested on ulcer margin biopsy using rapid urease test kit and confirmed on histopathological examination.Results: 136 consecutive patients of perforated peptic ulcer were included in this study with mean age of 42.43 years and sex ratio of 11.4:1. H. pylori infection was present in fifty four percent (54%) of patients. There was no relationship of H. pylori infection with morbidity and mortality of patients.Conclusions: H. pylori infection should be assessed at the time of primary surgical management on biopsy specimen using rapid urease test and confirmed on histopathological examination. All positive patients should be subjected to H. pylori eradication therapy.

scholarly journals High prevalence of duodenal ulcer in a tertiary care hospital in the city of São Paulo, SP, Brazil

2011 ◽  
Vol 48 (3) ◽  
pp. 171-174 ◽  
Author(s):  
Sergio B. Marques ◽  
Rejane Mattar ◽  
Everson L. A. Artifon ◽  
Paulo Sakai ◽  
Flair José Carrilho
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Male Gender ◽  
Care Hospital ◽  
Ulcer Disease ◽  
High Prevalence ◽  
H Pylori

CONTEXT: In spite of Helicobacter pylori infection being the etiological cause of peptic ulcer and its high prevalence in Brazil, the prevalence of peptic ulcer disease has been poorly studied. OBJECTIVES: To verify the peptic ulcer disease prevalence in patients of a tertiary care hospital. METHODS: Diagnostic findings from 1,478 consecutive endoscopies were correlated with the urease test results for H. pylori infection diagnosis and demographic data in a total of 3,779 endoscopies performed in 2005. The mean age of the patients was 51.14 ± 16.46, being 613 (41.5%) men. RESULTS: Peptic ulcer was diagnosed in 494 (33.4%) patients with a mean age of 54.86 ± 14.53, 205 (52%) were men, being 391 (26.5%) duodenal ulcer and 103 (7%) gastric ulcer. Normal endoscopy was found in 272 (18.4%) patients with a mean age of 38.4 ± 15.22, being 49 (18%) men. The comparison of peptic ulcer group with the patients that had normal endoscopy revealed that H. pylori infection [P = 0.005; OR = 1.70; 95% CI = 1.17-2.47][ign], male gender [P<0.0001; OR = 5.53; 95%CI = 3.67-8.34][ign] and older age [P<0.0001; OR = 1.08; 95%CI = 1.06-1.09] increased the risk of peptic ulcers. The overall H. pylori prevalence was 53% (786). CONCLUSIONS: Prevalence of duodenal ulcer is high in a Brazilian population that had H. pylori infection associated with older age and male gender as important determinants to gastrointestinal diseases outcome. Future prospective studies should confirm these findings.

scholarly journals Clinical profile of patients presenting with gastrointestinal bleeding in a tertiary care hospital

2017 ◽  
Vol 4 (6) ◽  
pp. 1616
Author(s):  
Chandan Kumar ◽  
Sumit Kumar Chakrabarti ◽  
Sucharita Chakraborty ◽  
Keshab Sinharay
Keyword(s):  
Peptic Ulcer ◽  
Gastrointestinal Bleeding ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Oesophageal Varices ◽  
Care Hospital ◽  
Gi Bleeding ◽  
Upper Gi Bleeding ◽  
Upper Gi ◽  
Gi Bleed

Background: It has been seen that Upper gastrointestinal bleeding (UGIB) is one of the most mutual gastrointestinal emergencies for physicians and surgeons. In the recent past studies, there is raised incidence of peptic ulcer with raised frequency of bleeding from it. The range of upper GI bleeding fluctuates from region to region and relies on the status of the centre in hospital hierarchy.Methods: An observational, cross-sectional, hospital-based, single centre study was carried out on 150 patients admitted in tertiary care hospital with the presentation of GI bleeding. A detailed patient history was taken followed by required clinical and laboratory investigations. Then patients were resuscitated and subjected to endoscopic procedure.Results: 150 patients were treated among which 105 were male (70%) and 45 females (30%). 111 patients (74%) had upper GI bleed, 28 patients (19%) had lower GI bleed, and 11 patients (7%) had obscure bleed. 41% of the population were diagnosed to have peptic ulcer (gastric or duodenal) as the cause behind GI bleed forming the main aetiology in this study population, 26% had oesophageal varices constituting second important cause of GI bleed, and 7% had obscure bleed. Those who had undergone UGI endoscopy or sigmoidoscopy or colonoscopy within last one month and who were having GI bleed following GI surgery were excluded from the study.Conclusions: It was seen that upper GI bleeding is more common than lower GI bleeding. Peptic ulcer was the chief cause resulting in gastrointestinal bleed followed by oesophageal varices. Gastrointestinal bleeding was more common in male population affecting mainly subjects over 40 years of age.

scholarly journals Perforation Peritonitis and the Developing World

ISRN Surgery ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Rajandeep Singh Bali ◽  
Sushant Verma ◽  
P. N. Agarwal ◽  
Rajdeep Singh ◽  
Nikhil Talwar
Keyword(s):  
Peptic Ulcer ◽  
Single Unit ◽  
Tertiary Care ◽  
Exploratory Laparotomy ◽  
Gastric Ulcers ◽  
Peptic Ulcer Perforation ◽  
Care Hospital ◽  
Duodenal Ulcers ◽  
Ulcer Disease ◽  
Perforation Peritonitis

Background. Perforation peritonitis is the one of the commonest emergency encountered by surgeons. The aim of this paper is to provide an overview of the spectrum of perforation peritonitis managed in a single unit of a tertiary care hospital in Delhi. Methods. A retrospective study was carried out between May 2010 and June 2013 in a single unit of the department of Surgery, Lok Nayak Hospital, Delhi. It included 400 patients of perforation peritonitis (diffuse or localized) who were studied retrospectively in terms of cause, site of perforation, surgical treatment, complications, and mortality. Only those patients who underwent exploratory laparotomy for management of perforation peritonitis were included. Results. The commonest cause of perforation peritonitis included 179 cases of peptic ulcer disease (150 duodenal ulcers and 29 gastric ulcers) followed by appendicitis (74 cases), typhoid fever (48 cases), tuberculosis (40 cases), and trauma (31). The overall mortality was 7%. Conclusions. Perforation peritonitis in India has a different spectrum as compared to the western countries. Peptic ulcer perforation, perforating appendicitis, typhoid, and tubercular perforations are the major causes of gastrointestinal perforations. Early surgical intervention under the cover of broad spectrum antibiotics preceded by adequate aggressive resuscitation and correction of electrolyte imbalances is imperative for good outcomes minimizing morbidity and mortality.

scholarly journals Perforated peptic ulcer (PPU): a one year review in tertiary care hospital in Uttarakhand, India

2017 ◽  
Vol 5 (1) ◽  
pp. 82
Author(s):  
Praveen Kumar ◽  
Nilkamal Kumar
Keyword(s):  
Peptic Ulcer ◽  
Effective Treatment ◽  
Open Surgery ◽  
Tertiary Care ◽  
Perforated Peptic Ulcer ◽  
Outcome Analysis ◽  
Peptic Ulcer Perforation ◽  
Care Hospital ◽  
Duration Of Symptoms ◽  
Omental Patch

Background: Peptic ulcer perforation is a common surgical emergency. The perforation usually involves the anterior wall of duodenum (60%), although, it might occur in antrum (20%) and lesser curvature of stomach (20%). Conventional open surgery involving repair with omental patch remains the gold standard treatment. This study evaluates the patterns and demographic factors associated with this common surgical disease and the outcome analysis of surgery in our state.Methods: The study was undertaken for patients admitted in surgery department in a single unit who underwent open surgery for perforated peptic ulcer. A total of 78 patients were assessed between January 2016 to January 2017.Results: The study found PPU to be a male dominated disease in fifth decade and with significant association with smoking and alcohol consumption. First part of duodenum being the commonest location of PPU, the peritoneal contamination was directly associated with the duration of symptoms. Wound infection was the most frequent post-operative complication. Simple repair with omental patch remains an effective treatment modality.Conclusions: Perforated peptic ulcer disease commonly affects middle aged males especially due to association with alcohol intake. Simple closure with omental patch followed by H. pylori eradication is an effective treatment modality.

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