scholarly journals Licochalcone A in Combination with Salicylic Acid as Fluid Based and Hydroxy-Complex 10% Cream for the Treatment of Mild Acne: A Multicenter Prospective Trial

2020 ◽  
Vol Volume 12 ◽  
pp. 961-967
Author(s):  
Federica Dall'Oglio ◽  
Gabriella Fabbrocini ◽  
Aurora Tedeschi ◽  
Marianna Donnarumma ◽  
Paolo Chiodini ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Prospective Trial ◽  
Licochalcone A

scholarly journals A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Kanokvalai Kulthanan ◽  
Suphattra Trakanwittayarak ◽  
Papapit Tuchinda ◽  
Leena Chularojanamontri ◽  
Pichaya Limphoka ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Acne Vulgaris ◽  
Maintenance Phase ◽  
Asian Population ◽  
Vehicle Group ◽  
Controlled Study ◽  
Licochalcone A ◽  
Acne Lesion ◽  
Significant Difference ◽  
The Mean

Many topical agents are available for treating the acute phase of acne; however, few agents have been proven beneficial during the maintenance phase. Objective. To evaluate the efficacy and safety of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid during the maintenance phase of mild to moderate acne in Thai patients. Methods. One hundred and ten patients with mild to moderate acne vulgaris were initially treated with a fixed combination of adapalene 0.1%/benzoyl peroxide 2.5% gel once daily for 8 weeks. Fifty patients who achieved at least 50% reduction in lesion counts or at least a 2-grade improvement in the Investigator’s Global Assessment (IGA) grade from baseline were enrolled in the maintenance phase, which was an investigator-masked, left-right comparison, randomized, controlled, intraindividual study. Moisturizers with and without the active study ingredients were applied twice a day to each side of the face, respectively, for 12 weeks. Assessments included acne lesion counts, acne severity by IGA scoring, skin bioengineering measurements, and skin tolerability as assessed by both patient and physician. Results. The treatment group had a significant reduction in the mean counts of noninflammatory, inflammatory, and total lesions compared to the vehicle group at week 12 and also between baseline and week 12. There was no significant difference in the mean scores for skin dryness, stinging/burning, or pruritus at any time point between groups. Conclusions. Moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid reduced acne lesions and prevented the development of new lesions during the maintenance phase. This trial is registered with ClinicalTrials.gov registration no. NCT04002024.

1152: Alpha-1 Receptor Blocking Therapy for Lower Ureteral Stones: A Randomized Prospective Trial

2004 ◽  
Vol 171 (4S) ◽  
pp. 304-304 ◽  
Author(s):  
Ali Tekin ◽  
Erdal Alkan ◽  
Melih Beysel ◽  
Ergin Yucebas ◽  
Ruknettin Aslan ◽  
...  
Keyword(s):  
Prospective Trial ◽  
Ureteral Stones ◽  
Receptor Blocking ◽  
Randomized Prospective Trial

Salicylic Acid in the Milk Trade

1877 ◽  
Vol 3 (53supp) ◽  
pp. 841-841
Author(s):  
L. Manetti ◽  
G. Muso
Keyword(s):  
Salicylic Acid
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