scholarly journals A Single-Centre Review of Transfusion Practices and Blood Wastage in Liver Transplantation

2019 ◽  
Vol Volume 11 ◽  
pp. 45-52
Author(s):  
Jo Han Gan ◽  
Kelly Nwankiti ◽  
Zoka Milan
Keyword(s):  
Liver Transplantation ◽  
Single Centre

Risk factors for primary poor function in liver transplantation: a retrospective single centre analysis

2019 ◽  
Author(s):  
M Fodor ◽  
A Woerdehoff ◽  
J Walte ◽  
S Neururer ◽  
H Esser ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Transplantation ◽  
Single Centre

Psychological support of children undergoing liver transplantation and their parents: a single-centre experience

1997 ◽  
Vol 1 (1) ◽  
pp. 19-24 ◽  
Author(s):  
G. Ullrich ◽  
A. Meyke ◽  
H. Haase ◽  
C. Erzfeld ◽  
S. Beckmann ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Psychological Support ◽  
Single Centre ◽  
Single Centre Experience

Causes of early acute graft failure after liver transplantation: analysis of a 17-year single-centre experience

2005 ◽  
Vol 19 (4) ◽  
pp. 492-500 ◽  
Author(s):  
Giovanni Varotti ◽  
Gian Luca Grazi ◽  
Gaetano Vetrone ◽  
Giorgio Ercolani ◽  
Matteo Cescon ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Failure ◽  
Single Centre ◽  
Single Centre Experience ◽  
Acute Graft

Orthotopic liver transplantation (OLT) using hepatitis C (HCV) viraemic donor organs for hepatitis C non‐viraemic recipients: A single‐centre experience

GastroHep ◽  
2020 ◽  
Vol 2 (6) ◽  
pp. 327-335
Author(s):  
Naemat Sandhu ◽  
Rohit Nathan ◽  
Eyob Feyssa ◽  
Nikolaos Chandolias ◽  
Victor Navarro ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C ◽  
Orthotopic Liver Transplantation ◽  
Single Centre ◽  
Single Centre Experience ◽  
Donor Organs

scholarly journals Prospective, single-centre, randomised controlled trial to evaluate the efficacy and safety of ischaemia-free liver transplantation (IFLT) in the treatment of end-stage liver disease

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e035374
Author(s):  
Changjun Huang ◽  
Shanzhou Huang ◽  
Yunhua Tang ◽  
Qiang Zhao ◽  
Dongping Wang ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Efficacy And Safety ◽  
Single Centre ◽  
Donor Liver ◽  
End Stage Liver Disease ◽  
Randomised Controlled ◽  
End Stage

IntroductionDuring conventional liver transplantation (CLT), ischaemia-reperfusion injury (IRI) is inevitable and is associated with complications such as early allograft dysfunction (EAD), primary non-function and ischaemic-type biliary lesions. We have established a novel procedure called ischaemia-free liver transplantation (IFLT). The results from a pilot study suggest that IFLT might prevent IRI and yield better transplant outcomes than CLT. The purpose of this study was to further assess the efficacy and safety of IFLT versus CLT in patients with end-stage liver disease.Methods and analysisThis is an investigator-initiated, open-label, phase III, prospective, single-centre randomised controlled trial on the effects of IFLT in patients with end-stage liver disease. Adult patients (aged 18–75 years) eligible for liver transplantation will be screened for participation in this trial and will be randomised between the IFLT group (n=34) and the CLT group (n=34). In the IFLT group, the donor liver will be procured, preserved and implanted with continuous normothermic machine perfusion (NMP). In the CLT group, the donor liver will be procured after a fast cold flush, preserved in 0°C–4°C solution and implanted under hypothermic and hypoxic conditions. Patients in both groups will be managed according to the standard protocol of our centre. The primary end point is the incidence of EAD after liver transplantation. Intraoperative and postoperative parameters of donor livers and recipients will be observed and recorded, and postoperative liver graft function, complications and recipient and graft survival will be evaluated. After a 12-month follow-up of the last enrolled recipient, the outcomes will be analysed to evaluate the safety and efficacy of IFLT versus CLT in patients with end-stage liver disease.Ethics and disseminationThe protocol was reviewed and approved by the Ethics Committee of The First Affiliated Hospital of Sun Yat-sen University. The findings will be disseminated to the public through conference presentations and peer-reviewed scientific journals.Trial registration numberChiCTR1900021158.

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