scholarly journals The structure and evolution of eye banking: a review on eye banks’ historical, present, and future contribution to corneal transplantation

2017 ◽  
Vol Volume 5 ◽  
pp. 23-40 ◽  
Author(s):  
Nathan Lambert ◽  
Winston Chamberlain
Keyword(s):  
Corneal Transplantation ◽  
Future Contribution ◽  
Eye Banking ◽  
Eye Banks

Fungal infection after keratoplasty and the role of antifungal supplementation to storage solution: a review

2019 ◽  
Vol 104 (8) ◽  
pp. 1036-1036 ◽  
Author(s):  
Tarika Thareja ◽  
Regis Kowalski ◽  
Roheena Kamyar ◽  
Deepinder Dhaliwal ◽  
Bennie H Jeng ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Fungal Infections ◽  
Corneal Transplantation ◽  
Eye Banking ◽  
Eye Banks ◽  
Corneal Toxicity ◽  
Randomised Control Trials ◽  
Corneal Storage ◽  
Storage Solution

Fungal infection after corneal transplantation is a rare, yet potentially devastating, postoperative complication and has become a growing concern for the transplant surgeon and eye banking community. The Eye Bank Association of America (EBAA) has reported an increasing trend in the rate of postkeratoplasty fungal infections and a reversal in the previously documented predominance of bacterial over fungal infections. Additionally, several studies have confirmed a high correlation between positive corneoscleral donor rim fungal cultures and postoperative infections. Optisol GS (Bausch & Lomb, Irvine, California, USA), the most extensively used corneal storage solution in US eye banks, does not currently contain any antifungal supplementation. Although large randomised control trials evaluating the efficacy and safety of routine antifungal supplementation to corneal storage solution are lacking, several investigative studies have assessed the role of antifungal agents in reducing fungal contamination of donor corneas without causing undue corneal toxicity. This review will present the current epidemiology of postkeratoplasty fungal infections and evidence for obtaining routine fungal rim cultures and antifungal supplementation of storage solution.

scholarly journals One threat, different answers: the impact of COVID-19 pandemic on cornea donation and donor selection across Europe

2020 ◽  
pp. bjophthalmol-2020-317938
Author(s):  
Gilles Thuret ◽  
Emilie Courrier ◽  
Sylvain Poinard ◽  
Philippe Gain ◽  
Marc Baud'Huin ◽  
...  
Keyword(s):  
Corneal Transplantation ◽  
Donor Selection ◽  
European Countries ◽  
Donor Pool ◽  
Eye Banking ◽  
Eye Banks ◽  
Selection Algorithms ◽  
Pandemic Severity ◽  
The Impact ◽  
The Relationship

ObjectivesTo assess to which extent the COVID-19 pandemic affected corneal transplantation by virtue of donor selection algorithms in different European countries.DesignSurvey.Setting110 eye banks in 26 European countries.Participants64 eye banks covering 95% of European corneal transplantation activity.InterventionsA questionnaire listing the number of corneas procured and distributed from February to May 2018–2020 was circulated to eye banks.Main outcome measuresThe primary outcome was the number of corneal procurements. Additional outcomes were national algorithms for donor selection, classified according to their stringency (donors with COVID-19 history, suspected for COVID-19, asymptomatic, PCR testing) and the pandemic severity in each country. We calculated Spearman’s correlation coefficient to determine, two by two, the relationship between the 3-month decline in eye banking activity (procurement), the stringency of donor selection algorithm and the grading of pandemic severity (cases and deaths). A partial correlation was run to determine the relationship between decline and stringency while controlling for pandemic severity.ResultsProcurements decreased by 38%, 68% and 41%, respectively, in March, April and May 2020 compared with the mean of the previous 2 years, while grafts decreased, respectively, by 28%, 68% and 56% corresponding to 3866 untreated patients in 3 months. Significant disparities between countries and the decrease in activity correlated with stringency in donor selection independent of pandemic severity.ConclusionsOur data demonstrate significant differences between countries regarding donor screening algorithms based on precautionary principles and, consequently, a decrease in the donor pool, already constrained by a long list of contraindications. Fundamental studies are needed to determine the risk of SARS-CoV-2 transmission by corneal transplantation and guide evidence-based recommendations for donor selection to justify their substantial medical and economic impact.

scholarly journals Aspectos clínicos e epidemiológicos relacionados ao transplante de córneas

2019 ◽  
Vol 13 ◽  
Author(s):  
Mayk Penze Cardoso ◽  
Marcos Antonio Ferreira Júnior ◽  
Elenilda De Andrade Pereira Gonçalves ◽  
Vanessa Giavarotti Taboza Flores ◽  
Élen Ferraz Teston ◽  
...  
Keyword(s):  
Health Services ◽  
Corneal Transplantation ◽  
Epidemiological Data ◽  
Distribution Patterns ◽  
Cross Sectional Study ◽  
The State ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Eye Banks ◽  
Mato Grosso Do Sul

RESUMOObjetivo: caracterizar epidemiologicamente os transplantes de córneas realizados no estado de Mato Grosso do Sul. Método: trata-se de estudo quantitativo, epidemiológico, de desenho transversal. Compor-se-á a amostra de estudo de forma censitária por todos os pacientes em fila de espera, os submetidos ao transplante de córneas e os doadores desse tipo de tecido no Estado de Mato Grosso do Sul. Realizar-se-á a coleta de dados por meio de três instrumentos elaborados para cada população distinta, com as variáveis de dados clínicos e epidemiológicos. Estabelecer-se-ão estatisticamente os padrões de distribuição e as frequências, bem como as medidas de tendência central, além da análise multivariada com aplicação de medidas de magnitude de efeito e associação, de acordo com a natureza de cada variável, a serem apresentados em forma de gráficos e tabelas. Resultados esperados: espera-se identificar as dificuldades encontradas no sistema estadual de transplante de córneas com foco no desenvolvimento de conceitos técnicos, de planejamento e organização do atendimento aos usuários em fila de espera, doadores e transplantados. Descritores: Transplante de Córnea; Doenças da Córnea; Retalhos de Tecido Biológico; Epidemiologia; Serviços de Saúde; Bancos de Olhos.ABSTRACTObjective: to make the clinical and epidemiological characterization of corneal transplants performed in the state of Mato Grosso do Sul. Method: this is a quantitative, epidemiological, cross-sectional study. A sample of the study will be collected in a census form for all patients in queue, those submitted to corneal transplantation and donors of this type of tissue in the State of Mato Grosso do Sul. Data collection will be performed by means of three instruments elaborated for each distinct population, with the variables of clinical and epidemiological data. Distribution patterns and frequencies as well as measures of central tendency will be statistically established, as well as multivariate analysis with application of magnitude of effect and association, according to the nature of each variable, to be presented in charts and tables. Expected results: it is hoped to identify the difficulties found in the state transplant system of corneal aimed at the development of technical concepts, planning and organization of care for waiting users, donors and transplanted patients. Keywords: Corneal Transplantation; Corneal Diseases; Biological Tissue Patchwork; Epidemiology; Health services; Eye Banks. Descriptors: Corneal Transplantation; Corneal Diseases; Free Tissue Flaps; Epidemiology; Health Services; Eye Banks.RESUMENObjetivo: caracterizar epidemiológicamente los trasplantes de córneas hechos en el estado de Mato Grosso do Sul. Método: trata-se de un estudio cuantitativo, epidemiológico, de diseño transversal. La muestra de estudio se compondrá de forma censal por todos los pacientes en cola de espera, los sometidos al trasplante de córneas y los donantes de ese tipo de tejido en el Estado de Mato Grosso do Sul. Se realizará la recolección de datos mediante tres instrumentos preparados para cada población distinta, con las variables de datos clínicos y epidemiológicos. Se establecerán estadísticamente los patrones de distribución y las frecuencias, así como las medidas de tendencia central, además del análisis multivariado con aplicación de medidas de magnitud de efecto y asociación, de acuerdo con la naturaleza de cada variable, que deberán presentarse en forma de gráficos y tablas. Resultados esperados: se espera identificar las dificultades encontradas en el sistema estatal de trasplante de córneas mirando el desarrollo de conceptos técnicos, de planificación y organización de la atención a los usuarios en cola de espera, los donantes y los trasplantados. Descriptores: Trasplante de Córnea; Enfermedades de Córnea; Colgajos Tisulares Libres; Epidemiología; Servicios de Salud; Bancos de Ojos.

The Evolution of Eye Banking and Corneal Transplantation

2013 ◽  
Vol 53 (2) ◽  
pp. 115-129 ◽  
Author(s):  
William B. Lee ◽  
Eric Meinecke ◽  
Bruce Varnum
Keyword(s):  
Corneal Transplantation ◽  
Eye Banking

Eye Banking and Corneal Transplantation Communicable Adverse Incidents

Cornea ◽  
2013 ◽  
Vol 32 (8) ◽  
pp. 1155-1166 ◽  
Author(s):  
Paul J. Dubord ◽  
G. Dewey Evans ◽  
Marian S. Macsai ◽  
Mark J. Mannis ◽  
David B. Glasser ◽  
...  
Keyword(s):  
Corneal Transplantation ◽  
Eye Banking

Ultrastructural Study of Corneas Stored at Room Temperature

1974 ◽  
Vol 32 ◽  
pp. 206-207
Author(s):  
D. L. Van Horn ◽  
H. J. Pederson
Keyword(s):  
Endothelial Cells ◽  
Ultrastructural Study ◽  
Room Temperature ◽  
Corneal Transplantation ◽  
Ultrastructural Changes ◽  
Corneal Epithelial ◽  
Donor Tissue ◽  
Donor Material ◽  
Eye Banks

Blindness due to loss of corneal transparency can often be corrected by corneal transplantation, however, the demand for donor tissue now exceeds the supply. Although there is little evidence to support the practice, most eye banks will not accept donor eyes unless they are removed from the cadaver within 6-8 hours after death and refrigerated. The purpose of this study was to determine if eyes can remain at room temperature longer than 8 hours before becoming unfit as donor material. Degenerative ultrastructural changes are described in the corneal epithelial, stromal and endothelial cells of eyes left in situ in cat cadavers at 22°C or removed and placed in sealed moist chambers at 22°C for various lengths of time.

scholarly journals Corneal transplantation and eye banking practices during COVID-19-related lockdown period in India from a network of tertiary eye care centers

2020 ◽  
Vol 68 (11) ◽  
pp. 2368
Author(s):  
Sunita Chaurasia ◽  
Arvind Roy ◽  
Sujata Das ◽  
Merle Fernandes ◽  
Somasheila Murthy
Keyword(s):  
Corneal Transplantation ◽  
Eye Care ◽  
Eye Banking
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