scholarly journals The Breast Tumor Microenvironment: Could Silicone Breast Implant Elicit Breast Carcinoma?

2021 ◽  
Vol Volume 13 ◽  
pp. 45-58
Author(s):  
Eduardo Fleury ◽  
Cristiane Nimir ◽  
Gabriel Salum D'Alessandro
Keyword(s):  
Tumor Microenvironment ◽  
Breast Carcinoma ◽  
Breast Tumor ◽  
Breast Implant ◽  
Silicone Breast Implant

ROS-responsive nanomedicine: Towards targeting the breast tumor microenvironment

2020 ◽  
Vol 28 ◽  
Author(s):  
RamaRao Malla ◽  
Mohammad Amjad Kamal
Keyword(s):  
Reactive Oxygen Species ◽  
Gene Therapy ◽  
Drug Resistance ◽  
Molecular Imaging ◽  
Tumor Microenvironment ◽  
Immune Cells ◽  
Breast Tumor ◽  
Imaging Techniques ◽  
Oxygen Species ◽  
Massive Accumulation

: The breast tumor microenvironment (TME) promotes drug resistance through an elaborated interaction of TME components mediated by reactive oxygen species (ROS). Despite a massive accumulation of data concerning the targeting the ROS, but little is known about the ROS-responsive nanomedicine for targeting breast TME. This review submits the ROS landscape in breast TME, including ROS biology, ROS mediated carcinogenesis, reprogramming of stromal and immune cells of TME. We also discussed ROS-based precision strategies for imaging TME, including molecular imaging techniques with advanced probes, multiplexed methods, and multi-omic profiling strategies. ROS-responsive nanomedicine also describes various therapies, such as chemo-dynamic, photodynamic, photothermal, sono-dynamic, immune, and gene therapy for BC. We expound ROS-responsive primary delivery systems for chemotherapeutics, phytochemicals, and immunotherapeutics. This review also presents recent updates on nano-theranostics for simultaneous diagnosis and treatment of BCs. We assume that review on this advancing field will be beneficial to the development of ROS-based nanotheranostics for BC.

Breast Tumor Microenvironment: Emerging target of therapeutic phytochemicals

Phytomedicine ◽  
2020 ◽  
Vol 70 ◽  
pp. 153227
Author(s):  
Rama Rao Malla ◽  
KGK Deepak ◽  
Neha Merchant ◽  
Venkata Ramesh Dasari
Keyword(s):  
Tumor Microenvironment ◽  
Breast Tumor

Doxycycline-Coated Silicone Breast Implant Reduces Surgical Site Infections Compared with Standard Gentamycin/Cefazolin/Bacitracin Wash

2018 ◽  
Vol 227 (4) ◽  
pp. S206-S207 ◽  
Author(s):  
Jennifer E. Baker ◽  
Ryan M. Boudreau ◽  
Aaron P. Seitz ◽  
Erich Gulbins ◽  
Michael Edwards ◽  
...  
Keyword(s):  
Breast Implant ◽  
Surgical Site Infections ◽  
Silicone Breast Implant

scholarly journals A STUDY ON THE HISTONE METHYLTRANSFERASE ENHANCER OF ZESTE HOMOLOG 2 EXPRESSION IN BREAST CARCINOMA

2020 ◽  
pp. 66-68
Author(s):  
Rubaiya Ahmad ◽  
Syed Meraj Imam ◽  
Debarshi Jana
Keyword(s):  
Breast Carcinoma ◽  
Breast Tumor ◽  
Triple Negative ◽  
Histone Methyltransferase ◽  
Expression Level ◽  
High Grade ◽  
Over Expression ◽  
Ezh2 Expression ◽  
Triple Negative Breast Carcinoma ◽  
Enhancer Of Zeste

The over expression of EZH2 in Breast Carcinoma. Compare EZH2 expression in different immunophenotypes of breast carcinoma(basal, luminal, triple-negative). The study EZH2 expression level in association to staging and grading of breast carcinoma Patients attending the Dept of Pathology, Sri Krishna Medical Collage Muzaffarpur, Bihar with epithelial breast tumor. We found that EZH2 in Breast Carcinoma was significantly associated with grade of the tumour. EZH2 was significantly associated with stage of the tumour. It was found that EZH2 was significantly correlated with ki67 in Breast Carcinoma patients. Triple negative Breast Carcinoma patient was significantly associated with high grade of EZH2 tumour.

Abstract P014: Driving immune-dependent metabolic vulnerabilities in the breast tumor microenvironment

2022 ◽  
Author(s):  
John Heath ◽  
Stephanie Totten ◽  
Young Kyuen Im ◽  
Valerie Sabourin ◽  
Kathryn Hunt ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Breast Tumor
Sign in / Sign up

Export Citation Format

Share Document