scholarly journals Double-strand break repair mechanisms in Escherichia coli: recent insights

2015 ◽  
pp. 35 ◽  
Author(s):  
Damir Đermić
Keyword(s):  
Escherichia Coli ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Repair Mechanisms ◽  
Break Repair

scholarly journals Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms

Genetics ◽  
2016 ◽  
Vol 203 (4) ◽  
pp. 1659-1668 ◽  
Author(s):  
Vasil Raykov ◽  
Marcus E. Marvin ◽  
Edward J. Louis ◽  
Laura Maringele
Keyword(s):  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Telomere Dysfunction ◽  
Repair Mechanisms ◽  
Break Repair

scholarly journals DNA double strand break repair in Escherichia coli perturbs cell division and chromosome dynamics

PLoS Genetics ◽  
2020 ◽  
Vol 16 (1) ◽  
pp. e1008473 ◽  
Author(s):  
Martin A. White ◽  
Elise Darmon ◽  
Manuel A. Lopez-Vernaza ◽  
David R. F. Leach
Keyword(s):  
Escherichia Coli ◽  
Cell Division ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Chromosome Dynamics ◽  
Dna Double Strand Break ◽  
Break Repair

scholarly journals Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51.

Genetics ◽  
1995 ◽  
Vol 139 (3) ◽  
pp. 1189-1199
Author(s):  
G T Milne ◽  
T Ho ◽  
D T Weaver
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Recombinational Repair ◽  
Multiple Alleles ◽  
Dna Double Strand Break ◽  
Repair Mechanisms ◽  
Break Repair ◽  
Insight Into

Abstract RAD52 function is required for virtually all DNA double-strand break repair and recombination events in Saccharomyces cerevisiae. To gain greater insight into the mechanism of RAD52-mediated repair, we screened for genes that suppress partially active alleles of RAD52 when mutant or overexpressed. Described here is the isolation of a phenotypic null allele of SRS2 that suppressed multiple alleles of RAD52 (rad52B, rad52D, rad52-1 and KlRAD52) and RAD51 (KlRAD51) but failed to suppress either a rad52 delta or a rad51 delta. These results indicate that SRS2 antagonizes RAD51 and RAD52 function in recombinational repair. The mechanism of suppression of RAD52 alleles by srs2 is distinct from that which has been previously described for RAD51 overexpression, as both conditions were shown to act additively with respect to the rad52B allele. Furthermore, overexpression of either RAD52 or RAD51 enhanced the recombination-dependent sensitivity of an srs2 delta RAD52 strain, suggesting that RAD52 and RAD51 positively influence recombinational repair mechanisms. Thus, RAD52-dependent recombinational repair is controlled both negatively and positively.

A soluble RecN homologue provides means for biochemical and genetic analysis of DNA double-strand break repair in Escherichia coli

DNA Repair ◽  
2009 ◽  
Vol 8 (12) ◽  
pp. 1434-1443 ◽  
Author(s):  
Jane I. Grove ◽  
Stuart R. Wood ◽  
Geoffrey S. Briggs ◽  
Neil J. Oldham ◽  
Robert G. Lloyd
Keyword(s):  
Escherichia Coli ◽  
Genetic Analysis ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Dna Double Strand Break ◽  
Break Repair

scholarly journals Escherichia coli radD (yejH)gene: a novel function involved in radiation resistance and double-strand break repair

2015 ◽  
Vol 95 (5) ◽  
pp. 754-768 ◽  
Author(s):  
Stefanie H. Chen ◽  
Rose T. Byrne ◽  
Elizabeth A. Wood ◽  
Michael M. Cox
Keyword(s):  
Escherichia Coli ◽  
Radiation Resistance ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Break Repair
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