Clinical and economic analysis of short-course versus standard-course antithymocyte globulin (rabbit) induction therapy in deceased-donor renal transplant recipients

2011 ◽  
Vol 68 (23) ◽  
pp. 2276-2282 ◽  
Author(s):  
Kwaku Marfo ◽  
Enver Akalin ◽  
Cuiling Wang ◽  
Amy Lu
Keyword(s):  
Renal Transplant ◽  
Economic Analysis ◽  
Induction Therapy ◽  
Antithymocyte Globulin ◽  
Deceased Donor ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Short Course

scholarly journals A Pharmacoeconomic Comparison of Antithymocyte Globulin and Muromonab CD3 Induction Therapy in Renal Transplant Recipients

1997 ◽  
Vol 11 (3) ◽  
pp. 237-245 ◽  
Author(s):  
Daniel C. Brennan ◽  
Mark A. Schnitzler ◽  
Jack D. Baty ◽  
Connie S. Ceriotti ◽  
Jeffrey A. Lowell ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Induction Therapy ◽  
Antithymocyte Globulin ◽  
Renal Transplant Recipients ◽  
Transplant Recipients

Antithymocyte Globulin (ATG) Induction Therapy and Disease Recurrence in Renal Transplant Recipients With Primary IgA Nephropathy

2008 ◽  
Vol 85 (10) ◽  
pp. 1505-1507 ◽  
Author(s):  
Francois Berthoux ◽  
Salem El Deeb ◽  
Christophe Mariat ◽  
Eric Diconne ◽  
Blandine Laurent ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Iga Nephropathy ◽  
Induction Therapy ◽  
Antithymocyte Globulin ◽  
Disease Recurrence ◽  
Renal Transplant Recipients ◽  
Transplant Recipients

scholarly journals FP873IMMUNOGLOBULIN INDUCTION THERAPY IN RENAL TRANSPLANT RECIPIENTS - FIVE YEAR DATA OF A PROSPECTIVE RANDOMIZED PILOT STUDY

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii369-iii369 ◽  
Author(s):  
Rolf Weimer ◽  
Bogumila Bartylak ◽  
Anne Staak ◽  
Fabrice Renner ◽  
Caner Suesal ◽  
...  
Keyword(s):  
Pilot Study ◽  
Renal Transplant ◽  
Induction Therapy ◽  
Renal Transplant Recipients ◽  
Transplant Recipients

scholarly journals Effects of Rituximab on the Development of Viral and Fungal Infections in Renal Transplant Recipients

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Samir J. Patel ◽  
Jennifer M. Devos ◽  
Richard J. Knight ◽  
Kyle L. Dawson ◽  
Wadi N. Suki ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Odds Ratio ◽  
Viral Infections ◽  
Fungal Infections ◽  
Graft Function ◽  
Deceased Donor ◽  
Infectious Complications ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

Background. Rituximab is becoming increasingly utilized in renal transplant recipients; however, its association with infections remains unclear. Methods. We reviewed the incidence of viral and fungal infections in kidney transplant recipients treated with () or without () rituximab (RTX) in addition to standard immunosuppression. Results. Infections occurred in 134 (30%) patients, with a greater proportion in RTX versus no RTX patients (47% versus 28%; ). Viral infections occurred in 44% and 27% of RTX and no RTX patients, respectively (). This was largely driven by the frequency of BK viremia and noncytomegalovirus/non-BK viruses in RTX patients (27% versus 13% () and 15% versus 2% (), resp.). Fungal infections also occurred more often in RTX patients (11% versus 3 %; ). Multivariate analysis revealed deceased donor recipient (odds ratio = 2.5; ) and rituximab exposure (odds ratio = 2.2; ) as independent risk factors for infection. Older patients, deceased donor recipients, those on dialysis longer, and those with delayed graft function tended to be at a greater risk for infections following rituximab. Conclusions. Rituximab is associated with an increased incidence of viral and fungal infections in kidney transplantation. Additional preventative measures and/or monitoring infectious complications may be warranted in those receiving rituximab.

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