scholarly journals Managing growing teratoma syndrome: new insights and clinical applications

2019 ◽  
Vol 5 (9) ◽  
pp. FSO419
Author(s):  
Srdjan Saso ◽  
Nicolas Galazis ◽  
Christos Iacovou ◽  
Kleio Kappatou ◽  
Menelaos Tzafetas ◽  
...  
Keyword(s):  
Literature Review ◽  
Germ Cell ◽  
Multidisciplinary Team ◽  
Ovarian Tumor ◽  
Management Plan ◽  
Lung Tumors ◽  
Clinical Applications ◽  
Growing Teratoma Syndrome ◽  
Abdominal Masses ◽  
Upper Abdominal

Although a recognized condition, growing teratoma syndrome (GTS) has no guidelines for management, and patients diagnosed with the condition are managed empirically by the most appropriate teams. We report a case of GTS in a 33-year-old patient who was initially treated with unilateral salpingo-oophorectomy and subsequent chemotherapy for a germ cell ovarian tumor. GTS was subsequently diagnosed with massive pelvic and upper abdominal masses as well as lung tumors. We also conducted a literature review on cases of GTS presenting with large tumors. Based on this, we suggest a management plan to guide the care of women with GTS. The condition is best managed in a multidisciplinary team involving the relevant surgeons, including gynecologist, abdominal and thoracic surgeons.

The case of prenatal diagnosis of a germ cell tumor of the fetal ovary

2018 ◽  
Author(s):  
N.N. Bondarenko, E.Yu. Andreeva , N.B. Filippova
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Ovarian Tumor ◽  
Ultrasound Examination ◽  
Abdominal Mass ◽  
Abdominal Cavity ◽  
Cell Tumor ◽  
Fetal Ovary ◽  
Entire Abdominal Cavity ◽  
Spontaneous Delivery

A case of prenatal ultrasound diagnosis of a rare congenital ovarian tumor is presented. By ultrasound examination at 36–37 weeks of gestation the intra-abdominal mass 66  47  74 mm occupying the entire abdominal cavity was discovered. At 38 weeks of pregnancy spontaneous delivery occurred with girl weight 2840 g. On the eighth day after birth the child has been successfully undergone surgery. Histological examination revealed congenital germ-cell tumor with structures of dysgerminoma and yolk sac tumor.

scholarly journals Geosites Inventory in Liguria Region (Northern Italy): A Tool for Regional Geoconservation and Environmental Management

2021 ◽  
Vol 13 (4) ◽  
pp. 2346
Author(s):  
Andrea Ferrando ◽  
Francesco Faccini ◽  
Flavio Poggi ◽  
Paola Coratza
Keyword(s):  
Risk Assessment ◽  
Environmental Management ◽  
Literature Review ◽  
Quantitative Assessment ◽  
Management Plan ◽  
Northern Italy ◽  
Value Assessment ◽  
Field Surveys ◽  
Environmental Management Plan ◽  
Use Values

The Liguria Region in Northern Italy is characterized by a wide geological and geomorphological variety, encompassing an important and valuable geoheritage. The Ligurian regional law (L.R. 39/2009) protects and enhances geodiversity and geosites, establishing the Regional Inventory of Geosites; however, an approved official inventory is still lacking. In this work, a first reasoned inventory of 120 geosites is proposed for the Liguria Region on the basis of field surveys and literature review. A quantitative assessment of the value and the degradation risk of geosites has been carried out: the value assessment takes into account scientific, additional and potential-for-use values; the degradation risk assessment considers geosites’ fragility and vulnerability. The results, providing knowledge on the Ligurian geoheritage, can serve as the basis for the Regional Inventory of Geosites and can be useful tools for the implementation of any regional geoconservation strategy or environmental management plan.

scholarly journals Multidisciplinary team management of 46,XY 17α-hydroxylase deficiency: a case report and literature review

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052199396
Author(s):  
Yang Zhou ◽  
Xue Xue ◽  
Panpan Shi ◽  
Qinrui Lu ◽  
Shulan Lv
Keyword(s):  
Multidisciplinary Team ◽  
Relevant Literature ◽  
Management Plan ◽  
Laboratory Evaluation ◽  
Primary Amenorrhea ◽  
Physical And Mental Health ◽  
Hydroxylase Deficiency ◽  
Holistic Management ◽  
Sexual Characteristics ◽  
Set Up

Background We report here a case study of 17α-hydroxylase deficiency in a phenotypic girl with male karyotype (46,XY). We also review the relevant literature to deepen our understanding of the disease, reduce the rate of missed diagnosis, and emphasize that holistic management of this disease requires collaborative multidisciplinary teamwork. Case presentation A 14-year-old patient with a female phenotype visited the endocrinology department because of hypertension. The patient had primary amenorrhea and lacked secondary sexual characteristics. Initial laboratory evaluation revealed normal levels of electrolytes, a hypergonadotropic hypogonadal state with high progesterone and low testosterone levels, and a 46,XY karyotype. She was referred to the urology department for gonadectomy and transferred to the gynecological endocrine clinic. On the basis of the patient’s medical history and genetic testing results, a diagnosis of 46,XY 17α-hydroxylase deficiency was made. The patient was provided with glucocorticoids, estrogens, metformin, and psychological support. Conclusions Patients with 17α-hydroxylase deficiency, a rare cause of congenital adrenal hyperplasia, should be treated by a multidisciplinary team. Relevant experts from different disciplines should set up a systematic and comprehensive individualized management plan to optimize the physical and mental health and quality of life of affected patients.

Borderline Ovarian Tumor in the Pediatric and Adolescent Population: A Case Series and Literature Review

2018 ◽  
Vol 31 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Krista J. Childress ◽  
Ninad Mohan Patil ◽  
Jodi A. Muscal ◽  
Jennifer E. Dietrich ◽  
Rajkumar Venkatramani
Keyword(s):  
Literature Review ◽  
Ovarian Tumor ◽  
Case Series ◽  
Borderline Ovarian Tumor ◽  
Adolescent Population

scholarly journals Metastatic Ovarian Tumor of Vulvar Malignant Melanoma in a 43-Year-Old Woman: A Case Report and Literature Review

2021 ◽  
Vol 11 (01) ◽  
pp. 1-11
Author(s):  
Yasuyuki Kawagoe ◽  
Midori Fujisaki ◽  
Tomoko Goto ◽  
Noriko Ueno ◽  
Junji Onishi ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Literature Review ◽  
Ovarian Tumor

scholarly journals Neuroblastoma with an unusual ovarian metastasis in a 5-year-old girl

2019 ◽  
Vol 12 (2) ◽  
pp. e226038
Author(s):  
Carla Steytler ◽  
Ahmed A Darwish ◽  
Sergey Popov ◽  
Cathy Morley-Jacob ◽  
Daniel C Aronson
Keyword(s):  
Complete Remission ◽  
Literature Review ◽  
Tumour Response ◽  
Pelvic Mass ◽  
Ovarian Metastasis ◽  
Gross Total Resection ◽  
Postoperative Treatment ◽  
Total Resection ◽  
Upper Abdominal

Neuroblastoma metastasizing to the ovary is rare. We report the 10th case and review the scarce literature. A 5-year-old girl with stage M neuroblastoma presented with an upper abdominal and a pelvic mass. Evaluation after induction showed very good tumour response with three remaining localisations: two abdominal and one pelvic. At gross total resection, the pelvic mass appeared to be the enlarged and abnormal right ovary and was removed completely. Pathology showed an ovarian metastasis. On completion of her postoperative treatment, she achieved complete remission. Literature review showed that underdiagnosing of ovarian metastasis in neuroblastoma is very likely.

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