scholarly journals Who owns your DNA?

BioTechniques ◽  
2021 ◽  
Author(s):  
Abigail Sawyer
Keyword(s):  

With the recent news that George Church is selling his genome as a nonfungible token and more unresolved murder cases being solved through familial DNA identification, BioTechniques is asking: who owns your DNA?

2018 ◽  
Vol 12 (1) ◽  
pp. 133-146
Author(s):  
Li’izza Diana Manzil

One sign of the rapidly growing world of medical science is its success in making one discovery about Deoxrybo Nucleid Acid (DNA). Islam does not prohibit the practice of DNA identification because it can be used in determining the legal status of relative relationships and related marital prohibitions among families because of the similarity of DNA genes between parents and their children. In Islam marriage prohibition can also occur between brothers and sisters. DNA identification can be done between siblings as a result of the presence of gene elements in breast milk. In addition, breast milk can also develop bone and grow meat if breastfeeding at least five times suction. But the results of DNA tests conducted between siblings cannot be more accurate if done to find relationships of parents and children. From this it clearly proves that Islamic medicine has an urgent value to Islamic law. This can be seen from one of its axiology in determining the status of brotherhood.


Science ◽  
2001 ◽  
Vol 294 (5541) ◽  
pp. 278-279 ◽  
Author(s):  
A. Lawler
Keyword(s):  

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 226
Author(s):  
Pamela Tozzo ◽  
Arianna Delicati ◽  
Anna Chiara Frigo ◽  
Luciana Caenazzo

Background and objectives: Over the last two decades, human DNA identification and kinship tests have been conducted mainly through the analysis of short tandem repeats (STRs). However, other types of markers, such as insertion/deletion polymorphisms (InDels), may be required when DNA is highly degraded. In forensic genetics, tumor samples may sometimes be used in some cases of human DNA identification and in paternity tests. Nevertheless, tumor genomic instability related to forensic DNA markers should be considered in forensic analyses since it can compromise genotype attribution. Therefore, it is useful to know what impact tumor transformation may have on the forensic interpretation of the results obtained from the analysis of these polymorphisms. Materials and Methods: The aim of this study was to investigate the genomic instability of InDels and STRs through the analysis of 55 markers in healthy tissue and tumor samples (hepatic, gastric, breast, and colorectal cancer) in 66 patients. The evaluation of genomic instability was performed comparing InDel and STR genotypes of tumor samples with those of their healthy counterparts. Results: With regard to STRs, colorectal cancer was found to be the tumor type affected by the highest number of mutations, whereas in the case of InDels the amount of genetic mutations turned out to be independent of the tumor type. However, the phenomena of genomic instability, such as loss of heterozygosity (LOH) and microsatellite instability (MSI), seem to affect InDels more than STRs hampering genotype attribution. Conclusion: We suggest that the use of STRs rather than InDels could be more suitable in forensic genotyping analyses given that InDels seem to be more affected than STRs by mutation events capable of compromising genotype attribution.


2021 ◽  
Vol 57 (5) ◽  
pp. 540-547
Author(s):  
A. O. Shamustakimova ◽  
Y. M. Mavlyutov ◽  
I. A. Klimenko

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Xiaoxiao Zhu ◽  
Hoi-Yan Wu ◽  
Pang-Chui Shaw ◽  
Wei Peng ◽  
Weiwei Su

Abstract Background Pheretima is a minister drug in Naoxintong capsule (NXTC), a well-known traditional Chinese medicine (TCM) formula for the treatment of cardiovascular and cerebrovascular diseases. Owing to the loss of morphological and microscopic characteristics and the lack of recognized chemical marker, it is difficult to identify Pheretima in NXTC. This study aims to evaluate the feasibility of using DNA techniques to authenticate Pheretima, especially when it is processed into NXTC. Methods DNA was extracted from crude drugs of the genuine and adulterant species, as well as nine batches of NXTCs. Based on mitochondrial cytochrome c oxidase subunit I (COI) gene, specific primers were designed for two genera of genuine species, Metaphire and Amynthas, respectively. PCR amplification was performed with the designed primers on crude drugs of Pheretima and NXTCs. The purified PCR products were sequenced and the obtained sequences were identified to species level with top hit of similarity with BLAST against GenBank nucleotide database. Results Primers MF2R2 and AF3R1 could amplify specific DNA fragments with sizes around 230–250 bp, both in crude drugs and NXTC. With sequencing and the BLAST search, identities of the tested samples were found. Conclusion This study indicated that the molecular approach is effective for identifying Pheretima in NXTC. Therefore, DNA identification may contribute to the quality control and assurance of NXTC.


2009 ◽  
Vol 30 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Aleksandar Apostolov ◽  
Stanislav Hristov ◽  
Ekaterina Angelova

1997 ◽  
Author(s):  
Victor Walter Weedn
Keyword(s):  

Author(s):  
T G Faleeva

In the review possible sources of dNA in sweat and fat substance are provided, and skin of the person is considered not only as a source of biological allocations, but also as a specific surface on which there is a possibility of detection of foreign imposings of a biological origin. The analysis of the existing methods of detection, fixing, collection, transportation and the subsequent molecular and genetic research dNA-containing of sweat and fat substance of the person is carried out. Approach to interpretation of results of genotyping of the biological objects containing small amount of genetic material is determined.


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