BASOPHIL ACTIVATION IN THE DIAGNOSIS OF LIFE-THREATENING HYPERSENSITIVITY REACTION TO IODINATED CONTRAST MEDIA: A CASE REPORT

2013 ◽  
Vol 68 (2) ◽  
pp. 140-142 ◽  
Author(s):  
E Philipse ◽  
V Sabato ◽  
C Bridts ◽  
L De Clerck ◽  
D Ebo
Keyword(s):  
Case Report ◽  
Hypersensitivity Reaction ◽  
Contrast Media ◽  
Basophil Activation ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast ◽  
Life Threatening

Why Reporting The Iodinated Contrast Media Used During Radiological Procedures Should Be Standard Practice: A Case Report

2016 ◽  
Vol 38 (10) ◽  
pp. e31
Author(s):  
D. Juricic Nahal ◽  
I. Cegec ◽  
V. Erdeljic Turk ◽  
M. Radacic Aumiler ◽  
K. Makar Ausperger ◽  
...  
Keyword(s):  
Case Report ◽  
Contrast Media ◽  
Iodinated Contrast Media ◽  
Standard Practice ◽  
Iodinated Contrast ◽  
Radiological Procedures

scholarly journals Iodinated contrast media

2021 ◽  
Vol 9 (1) ◽  
pp. 156-167
Author(s):  
Sami S. Alshowiman ◽  
Abdullah H Sahrah ◽  
Ayman K. Alswailem ◽  
Saud F. Alotaibi ◽  
Abdulaziz A. ALtowaijiri ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Media ◽  
Adverse Reactions ◽  
Iodinated Contrast Media ◽  
Radiographic Image ◽  
Complex Molecules ◽  
X Ray ◽  
Iodinated Contrast ◽  
Number Of Patients ◽  
Life Threatening

Contrast media are the materials utilized in radiology to improve the visualization of certain body structures subjected to analysis in a medical image. Contrast media are, then, diagnostic drugs because they increase the visibility of organs and tissues and allow the identification of details that otherwise could not be observed. With the introduction of multidetector computed tomography the number of patients undergoing contrast studies has grown exponentially in recent years. In computed tomography the formation of the radiographic image is obtained with the use of contrast media containing iodine atoms, exploiting the different attenuation that the X-ray beam presents in crossing the anatomical districts. The Iodinated Contrast Media (ICM) are a category of numerous substances formed by even complex molecules that vary considerably in their properties, uses and toxic effects. Even though iodinated contrast agents have a good safety profile, it is necessary to understand that some patients can have severe, life-threatening allergic reactions because of the side effects of the chemicals. This paper describes the clinical pharmacology, use and adverse reactions of intravenous iodinated contrast media used in computerized tomography, offering all doctors, even non-radiologists, the opportunity for rapid updating.

Skin tests for the exploration of hypersensitivity reactions associated with iodinated contrast media

2021 ◽  
Vol 16 ◽  
Author(s):  
Ahmed Zaiem ◽  
Syrine Ben Hammamia ◽  
Fares Ben Salem ◽  
Ons Charfi ◽  
Imen Aouinti ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Hypersensitivity Reaction ◽  
Contrast Media ◽  
Skin Testing ◽  
Skin Tests ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast ◽  
Intradermal Tests ◽  
The One

Background: Iodinated contrast media (ICM) are responsible for multiple side effects, especially hypersensitivity reactions. These reactions can either be authentic allergies, or non-allergic hypersensitivity reactions. Skin tests (prick and intradermal tests) are simple to perform and can be of great help, especially if the ICM need to be re-used. The aim of the study was to assess the characteristics of the patients in whom skin tests were performed, and the results of these tests. Methods: This is a retrospective study from June 2014 to June 2019. All included patients had at least one episode of hypersensitivity reaction to ICM and underwent skin tests. Results : We included 35 patients aged 18 to 85 years. The iopromide was the most implicated ICM. The reactions were mainly cutaneous (n=30) and immediate (n=27). The skin tests were negative, except for two patients. The reuse of ICM occured in 11 patients: 9 with an ICM other than the one suspected and two patients with the same ICM. Among these patients, 5 did not have any premedication. Two of them had a second hypersensitivity reaction, the first with another ICM and the second with the same ICM. Conclusion: One of the main pillars of allergic exploration is ICM skin testing, not only to prevent recurrence, but also to allow patients to benefit from ICM reuse, which are sometimes essential.

Skin tests in patients with hypersensitivity reaction to iodinated contrast media: a meta-analysis

Allergy ◽  
2015 ◽  
Vol 70 (6) ◽  
pp. 625-637 ◽  
Author(s):  
S. H. Yoon ◽  
S.-Y. Lee ◽  
H.-R. Kang ◽  
J.-Y. Kim ◽  
S. Hahn ◽  
...  
Keyword(s):  
Hypersensitivity Reaction ◽  
Contrast Media ◽  
Meta Analysis ◽  
Skin Tests ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast

scholarly journals Relapse of Sulfasalazine-induced DRESS Syndrome Following the Administration of Contrast Media: A Case Report

2021 ◽  
Author(s):  
Niayesh Mohebbi ◽  
Hamidreza Taghvaye Masoumi ◽  
Malihe Khosravi Khezri ◽  
Mona Talaschian
Keyword(s):  
Drug Reaction ◽  
Case Report ◽  
Contrast Media ◽  
Acute Exacerbation ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Dress Syndrome ◽  
Iodinated Contrast ◽  
Systemic Symptoms ◽  
High Possibility

Sulfasalazine, a non-antibiotic sulfonamide, is associated with severe hypersensitivity reactions, including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. We report a case of sulfasalazine-induced DRESS syndrome that relapsed following the administration of visipaque® (iodixanol). Macular rashes, pruritus, and an acute exacerbation of dyspnea were immediately observed after the administration of contrast media. It seems that patients suffering from DRESS syndrome are sensitive to the administration of other new medications with a high possibility of hypersensitive reactions. It can be concluded that iodinated contrast media should be used cautiously in patients with DRESS syndrome.

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