A NTICONVULSANT HYPERSENSITIVITY SYNDROME MIMICKING A VIRAL ILLNESS WITH SKIN RASH: A CASE REPORT

2013 ◽  
Vol 68 (3) ◽  
pp. 232-233 ◽  
Author(s):  
V Gérard ◽  
E Delgrange ◽  
C de Halleux ◽  
D Vanpee
Keyword(s):  
Case Report ◽  
Skin Rash ◽  
Hypersensitivity Syndrome ◽  
Viral Illness

scholarly journals Lamotrigine Associated DRESS Syndrome – a Case Report

2015 ◽  
Vol 7 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Jagoda Balaban ◽  
Đuka Ninković-Baroš
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Skin Rash ◽  
Respiratory Symptoms ◽  
Hypersensitivity Syndrome ◽  
Organ Involvement ◽  
Dress Syndrome ◽  
Drug Induced ◽  
Drug Rash ◽  
Systemic Symptoms

AbstractDrug-induced delayed multiorgan hypersensitivity syndrome, also known as drug rash (reaction) with eosinophilia and systemic symptoms (DRESS) syndrome, represents a drug-induced cluster of skin, hematologic and systemic symptoms. More than forty drugs have been associated with this syndrome. We present a case of DRESS syndrome suspecting that lamotrigine was directly responsible for the patient’s rash and other symptoms. A female patient presented with extensive skin rash, fever, hematologic abnormalities, organ involvement such as hepatitis, pancreatitis and respiratory symptoms. The symptoms developed four weeks after the initiation of the offending drug, and disappeared eight weeks after its discontinuation.

scholarly journals Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report

2020 ◽  
Vol 4 (2) ◽  
pp. 244-246
Author(s):  
Orhay Mirzapolos ◽  
Perry Marshall ◽  
April Brill
Keyword(s):  
Emergency Medicine ◽  
Case Report ◽  
Brugada Syndrome ◽  
Ventricular Arrhythmias ◽  
Cardiac Monitoring ◽  
St Segment Elevation ◽  
Cardioverter Defibrillator ◽  
St Segment ◽  
Viral Illness ◽  
Automatic Implantable Cardioverter Defibrillator

Introduction: Brugada syndrome is an arrhythmogenic disorder that is a known cause of sudden cardiac death. It is characterized by a pattern of ST segment elevation in the precordial leads on an electrocardiogram (EKG) due to a sodium channelopathy. Case Report: This case report highlights the case of a five-year-old female who presented to the emergency department with a febrile viral illness and had an EKG consistent with Brugada syndrome. Discussion: Fever is known to accentuate or unmask EKG changes associated with Brugada due to temperature sensitivity of the sodium channels. Conclusion: Febrile patients with Brugada are at particular risk for fatal ventricular arrhythmias and fevers should be treated aggressively by the emergency medicine provider. Emergency medicine providers should also consider admitting febrile patients with Brugada syndrome who do not have an automatic implantable cardioverter-defibrillator for cardiac monitoring.

AZATHIOPRINE HYPERSENSITIVITY SYNDROME: A CASE REPORT

2013 ◽  
Vol 68 (3) ◽  
pp. 223-224 ◽  
Author(s):  
S Fenaux ◽  
M Tintillier ◽  
Ch Cuvelier ◽  
G Migali ◽  
JM Pochet
Keyword(s):  
Case Report ◽  
Hypersensitivity Syndrome

scholarly journals Autoimmune hemolytic anemia associated with vitamin B12 deficiency and viral illness in DiGeorge syndrome. Case report and literature review.

2021 ◽  
Author(s):  
Zohaib Yousaf ◽  
Fateen Ata ◽  
Phool Iqbal ◽  
Bassam Muthanna ◽  
Adeel Khan ◽  
...  
Keyword(s):  
Case Report ◽  
Digeorge Syndrome ◽  
Vitamin B12 Deficiency ◽  
Intravenous Immunoglobulins ◽  
Chromosome 22 ◽  
Thrombocytopenic Purpura ◽  
Immunodeficiency Disorder ◽  
Viral Illness ◽  
B12 Deficiency ◽  
Intravenous Steroids

DiGeorge syndrome, an immunodeficiency disorder due to long arm microdeletion of chromosome 22. Isolated hemolysis is rarely seen in DiGeorge syndrome and is usually reported in conjunction with idiopathic thrombocytopenic purpura. We report a case of DiGeorge syndrome with AIHA, which was successfully managed by intravenous steroids and intravenous immunoglobulins.

COVID-19 may present with an itchy erythematous papular rash: a case report

2020 ◽  
Author(s):  
Alice Serafini ◽  
Peter K. Kurotschka ◽  
Mariabeatrice Bertolani ◽  
Silvia Riccomi
Keyword(s):  
Case Report ◽  
Skin Rash ◽  
Clinical Manifestations ◽  
Primary Care Providers ◽  
Small Scale ◽  
Correct Identification ◽  
Case Detection ◽  
Care Providers ◽  
Early Presentation ◽  
Skin Manifestations

Abstract Background: the most commonly reported clinical manifestations of Coronavirus Disease (COVID- 19) are: fever, fatigue, dry cough, anorexia, myalgias, dyspnoea and sputum production. Other, rarer, manifestations include headache, sore throat, rhinorrhoea, nausea, diarrhoea and olfactory or taste disorders. Two recent small-scale studies suggest the possibility of a skin rash being a clinical presentation of the disease. The purpose of our case report is to bring attention to an atypical presentation of the disease (skin rash) and reflect on the importance of the correct identification of COVID-19 suspicious symptoms as part of the crucial activity of case-finding in primary care.Case presentation: the patient is an Italian 32 years old female nurse who has had several close contacts to COVID-19 cases during her working shifts. On the 13 th March 2020 she developed an itchy erythematous papular rash sparing only her sparing only her face, scalp and abdomen. One week later she developed fever and diarrhoea. During the first week of remote assessment carried out by her General Practitioner (GP), she gradually developed a dry cough, intermittent fever and diarrhoea. At the time of article submission (31 days after the symptoms onset), she has not completely recovered and is still suffering of a dry cough, headache, fatigue and, occasionally, diarrhoea.Conclusions: this study suggest that skin manifestations could be an early presentation of COVID-19 and, during outbreaks, they should be taken into proper account by primary care providers as possibly caused by Sars-Cov-2. Early identification of COVID-19 patients is a crucial part of the strategy of case detection and case isolation, which has shown to be crucial in the reduction of incidence and COVID-19-related mortality. Further research is needed to establish frequency, symptoms, signs, pathogenesis and role in case detection of skin manifestations in COVID-19 patients.

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