scholarly journals 2SH-05 Two-photon imaging of the mouse motor cortex during voluntary skilled movement(2SH Star of life shined by frontier microscopies,Symposium,The 50th Annual Meeting of the Biophysical Society of Japan)

2012 ◽  
Vol 52 (supplement) ◽  
pp. S16
Author(s):  
Riichiro Hira ◽  
Fuki Ohkubo ◽  
Katsuya Ozawa ◽  
Yoshikazu Isomura ◽  
Kazuo Kitamura ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Annual Meeting ◽  
Skilled Movement ◽  
Two Photon ◽  
Biophysical Society ◽  
Photon Imaging ◽  
Two Photon Imaging

scholarly journals Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Teppei Ebina ◽  
Yoshito Masamizu ◽  
Yasuhiro R. Tanaka ◽  
Akiya Watakabe ◽  
Reiko Hirakawa ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Neuronal Activity ◽  
Upper Limb ◽  
Limb Movement ◽  
Two Photon ◽  
Photon Imaging ◽  
Two Photon Imaging

scholarly journals Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Eric M. Trautmann ◽  
Daniel J. O’Shea ◽  
Xulu Sun ◽  
James H. Marshel ◽  
Ailey Crow ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Rhesus Macaque ◽  
Cortical Neurons ◽  
Imaging System ◽  
Movement Direction ◽  
Calcium Signals ◽  
Two Photon ◽  
Large Populations ◽  
Photon Imaging ◽  
Two Photon Imaging

AbstractCalcium imaging is a powerful tool for recording from large populations of neurons in vivo. Imaging in rhesus macaque motor cortex can enable the discovery of fundamental principles of motor cortical function and can inform the design of next generation brain-computer interfaces (BCIs). Surface two-photon imaging, however, cannot presently access somatic calcium signals of neurons from all layers of macaque motor cortex due to photon scattering. Here, we demonstrate an implant and imaging system capable of chronic, motion-stabilized two-photon imaging of neuronal calcium signals from macaques engaged in a motor task. By imaging apical dendrites, we achieved optical access to large populations of deep and superficial cortical neurons across dorsal premotor (PMd) and gyral primary motor (M1) cortices. Dendritic signals from individual neurons displayed tuning for different directions of arm movement. Combining several technical advances, we developed an optical BCI (oBCI) driven by these dendritic signalswhich successfully decoded movement direction online. By fusing two-photon functional imaging with CLARITY volumetric imaging, we verified that many imaged dendrites which contributed to oBCI decoding originated from layer 5 output neurons, including a putative Betz cell. This approach establishes new opportunities for studying motor control and designing BCIs via two photon imaging.

Biocompatible well-defined chromophore–polymer conjugates for photodynamic therapy and two-photon imaging

2013 ◽  
Vol 4 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Cristina Cepraga ◽  
Thibault Gallavardin ◽  
Sophie Marotte ◽  
Pierre-Henri Lanoë ◽  
Jean-Christophe Mulatier ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Two Photon ◽  
Polymer Conjugates ◽  
Photon Imaging ◽  
Two Photon Imaging
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