scholarly journals Effect of Breed, Heterosis and Sex on Body Weight, and Glutathione Peroxidase Activities in Red Blood Cell Haemolysate and Blood Plasma at the Age of Sexual Maturity in Chickens

2008 ◽  
Vol 45 (3) ◽  
pp. 180-185
Author(s):  
Gihan F. Shaaban ◽  
Eissa E. Ahmed ◽  
Miklós Mézes
2010 ◽  
Vol 79 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Mária Weber ◽  
Krisztián Balogh ◽  
Judit Fodor ◽  
Márta Erdélyi ◽  
Zsolt Ancsin ◽  
...  

The effect of T-2 and HT-2 toxin using different doses in the starter (0-21 days: 1.04 mg T-2 toxin and 0.49 mg HT-2 toxin kg-1feed), and finisher diets (22-39 days: 0.12 mg T-2 toxin and 0.02 mg HT-2 toxin kg-1feed) was investigated in broiler chickens. Birds were divided into two groups fed with control and T-2 and HT-2 toxin contaminated diets. Pathological signs of toxicity were investigated on days 21 and 39 of the trial, individual liveweight was measured weekly. Five birds from each group were sacrificed on the 21st and 39th days of treatment, when blood plasma, red blood cell, liver and kidney samples were taken, in which malondialdehyde and reduced glutathione concentration and glutathione-peroxidase activity were determined. Pathological signs (lesions in the oral cavity and on the tongue, inflammation in the small intestine) were found in the group fed T-2 and HT-2 toxin contaminated feed on day 21 compared to control. Body weight was significantly lower as a result of feeding T-2 and HT-2 toxin contaminated diet. However, the contamination did not cause a significant increase of malondialdehyde content in the analysed tissues. Reduced glutathione content was significantly lower in the liver homogenate on day 39 than that of the control. Glutathione peroxidase activity also did not differ significantly in blood plasma, red blood cell haemolysates and kidney homogenates, while it was significantly higher in the liver homogenates of the mycotoxin-challenged birds. In conclusion, it can be stated that T-2 and HT-2 toxin exposure has long-term effects in broiler chickens.


2021 ◽  
Vol 19 ◽  
pp. 107-113
Author(s):  
P. A. Onyeyili ◽  
F. A. Ameh ◽  
B. S. Paul

Toxicity studies of 0,0-diethyl-0-(2- isoprophyl-6-methyl-4-pyrimidinyl) phosphorothioate (DiazinonR) was carried out in the Balami breed of sheep. The agent was administered orally daily for one week at the rate of 20, 25 and 30mg/kg body weight to groups of sheep. The 30mg/kg dose produced transient clinical signs in the sheep. Diazinon inhibited plasma and red blood cell cholinesterase activity. The intensity of the inhibition was more with 30mg/kg dose and occurred as from day 3 and lasted till the end of the investigation 7 days post treatment. Leucocytosis was also observed with the 30mg/kg dose. There was no observable effect of the chemical on the RBC, Hb, and PCV values in sheep at the dosages used.


1979 ◽  
Vol 27 (6) ◽  
pp. 913 ◽  
Author(s):  
JL Barnett ◽  
RA How ◽  
WF Humphreys

Age, sex and seasonal related changes in body weight and blood parameters were determined for T caninus and T. vulpecula, whose distribution overlapped in part of the study area. In T. caninus age-related changes occurred in body weight, mean plasma glucose and protein concentrations and haematocrit. Seasonal changes occurred in plasma glucose and protein concentrations, haemoglobin concentration and red blood cell count. There were sexual dimorphisms in haematocrit, haemoglobin concentration and red blood cell count in both species; the mean values were greater in males. T. vulpecula also exhibited a sexual dimorphism in body weight (males > females). The only seasonal change in T. vulpecula was in haemoglobin concentration. Comparison of the species as adults showed that T. caninus had higher mean levels of body weight, haematocrit and haemoglobin concentration, while plasma lipid concentration and red blood cell counts were greater in T vulpecula. These species differences may be a reflection of the diets of the two species. In addition the measured parameters showed greater seasonal variation in T. caninus, a K-selected species, than in T. vulpecula, which is more r-selected.


Author(s):  
Maria Hadjinicolaou ◽  
Eleftherios Protopapas

A mathematical tool, namely the Kelvin transformation, has been employed in order to derive analytical expressions for important hydrodynamic quantities, aiming to the understanding and to the study of the blood plasma flow past a Red Blood Cell (RBC). These quantities are the fluid velocity, the drag force exerted on a cell and the drag coefficient. They are obtained by employing the stream function ? which describes the Stokes flow past a fixed cell. The RBC, being a biconcave disk, has been modelled as an inverted prolate spheroid. The stream function is given as a series expansion in terms of Gegenbauer functions, which converge fast. Therefore we employ only the first term of the series in order to derive simple and ready to use analytical expressions. These expressions are important in medicine, for studying, for example the transportation of oxygen, or the drug delivery to solid tumors.


2010 ◽  
Vol 299 (3) ◽  
pp. H908-H914 ◽  
Author(s):  
Julien Tripette ◽  
Gylna Loko ◽  
Abdoulaye Samb ◽  
Bertin Doubi Gogh ◽  
Estelle Sewade ◽  
...  

This study compared the hemorheological responses of a group of sickle cell trait (SCT) carriers with those of a control (Cont) group in response to 40 min of submaximal exercise (exercise intensity, 55% aerobic peak power) performed in two conditions: one with water offered ad libitum, i.e., the hydration (Hyd) condition, and one without water, i.e., the dehydration (Dehyd) condition. Blood and plasma viscosities, as well as red blood cell rigidity, were determined at rest, at the end of exercise, and at 2 h recovery with a cone plate viscometer at high shear rate and 37°C. The SCT and Cont groups lost 1 ± 0.7 and 1.6 ± 0.6 kg of body weight, respectively, in the Dehyd condition, indicating a significant effect of water deprivation compared with the Hyd condition, in which body weight remained unchanged. Plasma viscosity increased with exercise and returned to baseline during recovery independently of the group and condition. As previously demonstrated, resting blood viscosity was greater in the SCT carriers than in the Cont group. Blood viscosity increased by the end of exercise and returned to baseline at 2 h recovery in the Cont group in both conditions. The blood viscosity of SCT carriers did not change in response to exercise in the Dehyd condition and remained elevated at 2 h recovery. This extended hyperviscosity, in association with other biological changes induced by exercise, could be considered as a risk factor for exercise-related events in SCT carriers, similar to vasoocclusive crises, notably during the recovery. In contrast, the Hyd condition normalized the hyperviscosity and red blood cell rigidity of the SCT carriers, with blood viscosity values reaching the same lower values as those found in the Cont group during the recovery. Adequate hydration of SCT carriers should be strongly promoted to reduce the clinical risk associated with potential hyperviscosity complications.


1960 ◽  
Vol 198 (6) ◽  
pp. 1177-1180 ◽  
Author(s):  
Robert J. Dellenback ◽  
Gerhard H. Muelheims

The distribution of red blood cells in nine normal Nembutalized rats (323.2–415.0 gm body weight) was determined by the Cr51-labeled red blood cell technique. Microliters of red blood cells per total and per gram of tissue are reported for the testes, brain, intestine, kidney, heart-lung, spleen, liver, bone, muscle and skin. Values are also listed for the same organs and tissues determined after rapid bleed-out as found by Muelheims, Dellenback and Rawson. A comparison of these values shows that the liver, heart-lung and muscle contribute approximately 80% of all red blood cells removed in the hemorrhage. The skin, bone, kidney and intestine contribute as a group the remaining 20% with a negligible contribution from the testes and brain and no contribution from the spleen.


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