scholarly journals Influence of Intracerebroventricular Administration of Morphine and Kyotorphin on Food Intake of the Neonatal Chick.

1999 ◽  
Vol 36 (5) ◽  
pp. 319-324 ◽  
Author(s):  
Takashi BUNGO ◽  
Ryuichi ANDO ◽  
Ryutaro AO ◽  
Masataka SHIMOJO ◽  
Yasuhisa MASUDA ◽  
...  
Keyword(s):  
Food Intake ◽  
Intracerebroventricular Administration ◽  
Neonatal Chick

Neuropeptide Y increases food intake in mice

1987 ◽  
Vol 253 (3) ◽  
pp. R516-R522 ◽  
Author(s):  
J. E. Morley ◽  
E. N. Hernandez ◽  
J. F. Flood
Keyword(s):  
Food Intake ◽  
Neuropeptide Y ◽  
Water Intake ◽  
Free Acid ◽  
Behavioral Analysis ◽  
Intracerebroventricular Administration ◽  
Diabetic Mice ◽  
Number Of Species ◽  
Genetically Diabetic Mice ◽  
Old Mice

Neuropeptide Y (NPY) stimulates eating in a number of species. In the studies reported here, intracerebroventricular administration of porcine NPY increased eating in mice. In the presence of food, NPY caused enhancement of water intake, whereas in the absence of food, NPY suppressed water intake. Behavioral analysis showed that NPY decreased the latency to eat, increased the time spent eating, and decreased grooming. Human NPY also increased food intake, whereas the free acid of NPY was inactive. Although some minor discrepancies in response were noted overall, NPY was as effective at stimulating food intake in genetically obese (ob/ob) mice compared with their lean littermates (ob/-), in genetically diabetic mice (db/db) and their nondiabetic heterozygote control (db/m), in streptozocin-induced diabetic mice and their controls, and in adult (8 mo old) compared with old (25 mo old) mice.

Intracerebroventricular Administration of Soy Protein Hydrolysates Reduces Body Weight without Affecting Food Intake in Rats

2007 ◽  
Vol 63 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Nerissa Vaughn ◽  
Anthony Rizzo ◽  
Dolores Doane ◽  
J. Lee Beverly ◽  
Elvira Gonzalez de Mejia
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Soy Protein ◽  
Protein Hydrolysates ◽  
Intracerebroventricular Administration ◽  
Soy Protein Hydrolysates

Stimulatory effect of intracerebroventricular administration of orexin A on food intake in the zebrafish, Danio rerio

Peptides ◽  
2011 ◽  
Vol 32 (7) ◽  
pp. 1357-1362 ◽  
Author(s):  
Eri Yokobori ◽  
Kenji Kojima ◽  
Morio Azuma ◽  
Ki Sung Kang ◽  
Sho Maejima ◽  
...  
Keyword(s):  
Food Intake ◽  
Danio Rerio ◽  
Intracerebroventricular Administration ◽  
Orexin A

Effect of food intake on protein and RNA metabolism in neonatal chick liver

1989 ◽  
Vol 9 (7) ◽  
pp. 785-790 ◽  
Author(s):  
Tatsuzo Oka ◽  
Sang Ho Kweon ◽  
Yasuo Natori ◽  
Norihiko Hasegawa
Keyword(s):  
Food Intake ◽  
Rna Metabolism ◽  
Neonatal Chick ◽  
Effect Of Food

Melanin-concentrating hormone: a functional melanocortin antagonist in the hypothalamus

1998 ◽  
Vol 274 (4) ◽  
pp. E627-E633 ◽  
Author(s):  
David S. Ludwig ◽  
Kathleen G. Mountjoy ◽  
Jeffrey B. Tatro ◽  
Jennifer A. Gillette ◽  
Robert C. Frederich ◽  
...  
Keyword(s):  
Food Intake ◽  
Mammalian Brain ◽  
Receptor Subtypes ◽  
Dependent Manner ◽  
Intracerebroventricular Administration ◽  
Melanocyte Stimulating Hormone ◽  
Molar Excess ◽  
Melanin Concentrating Hormone ◽  
Skin Coloration ◽  
Dose Dependent

Melanin-concentrating hormone (MCH) and α-melanocyte-stimulating hormone (α-MSH) demonstrate opposite actions on skin coloration in teleost fish. Both peptides are present in the mammalian brain, although their specific physiological roles remain largely unknown. In this study, we examined the interactions between MCH and α-MSH after intracerebroventricular administration in rats. MCH increased food intake in a dose-dependent manner and lowered plasma glucocorticoid levels through a mechanism involving ACTH. In contrast, α-MSH decreased food intake and increased glucocorticoid levels. MCH, at a twofold molar excess, antagonized both actions of α-MSH. α-MSH, at a threefold molar excess, blocked the orexigenic properties of MCH. MCH did not block α-MSH binding or the ability of α-MSH to induce cAMP in cells expressing either the MC3 or MC4 receptor, the principal brain α-MSH receptor subtypes. These data suggest that MCH and α-MSH exert opposing and antagonistic influences on feeding behavior and the stress response and may function in a coordinate manner to regulate metabolism through a novel mechanism mediated in part by an MCH receptor.

Orexin-A does not stimulate food intake in old rats

2004 ◽  
Vol 287 (6) ◽  
pp. G1182-G1187 ◽  
Author(s):  
Saeko Takano ◽  
Setsuko Kanai ◽  
Hiroko Hosoya ◽  
Minoru Ohta ◽  
Hiroshi Uematsu ◽  
...  
Keyword(s):  
Food Intake ◽  
Protein Level ◽  
Lateral Ventricle ◽  
Recovery Period ◽  
Dependent Manner ◽  
Intracerebroventricular Administration ◽  
Orexin A ◽  
Young Rats ◽  
Left Lateral Ventricle ◽  
Old Rats

Aging is associated with a progressive decrease in appetite and food intake. Both A and B orexins, expressed in specific neurons of the lateral hypothalamic area, have been implicated in the regulation of sleep and feeding. In this study, the stimulatory effect of intracerebroventricular administration of the orexins on food intake was compared between young (4-mo-old) and old (25- to 27-mo-old) male Wistar rats. A stainless steel cannula was implanted stereotactically into the left lateral ventricle. After a 7-day recovery period, different doses (0–30 nmol) of orexins were injected into the left lateral ventricle without anesthesia. Food and water consumptions were measured at 1, 2, and 4 h after injection. The protein levels of orexin receptors, a specific receptor for orexin-A (OX1R) and a receptor for both orexin-A and -B (OX2R), in the hypothalamus were determined by Western blot analysis and compared between young and old rats. Intracerebroventricular administration of orexin-A stimulated food intake in a dose-dependent manner in young rats. However, no effects were observed at any dose in old rats. The protein level of OX1R in the hypothalamus was significantly lower in old rats than in young rats, although the protein level of OX2R was comparable between groups. Results of the present study indicate that the function of the orexin system is diminished in old rats. The decrease in the OX1R protein level in the hypothalamus could be responsible for orexin-A's lack of stimulation of food intake in old rats.

Sign in / Sign up

Export Citation Format

Share Document