scholarly journals In vitro Antibacterial Efficacy of Non-Antibiotic Growth Promoters in Poultry Industry

2020 ◽  
Vol 57 (1) ◽  
pp. 45-54
Author(s):  
Mashael R. Aljumaah ◽  
Manal M. Alkhulaifi ◽  
Alaeldein M. Abudabos
Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3368
Author(s):  
Héloïse Côté ◽  
André Pichette ◽  
Alexis St-Gelais ◽  
Jean Legault

The use of growth-promoting antibiotics in livestock faces increasing scrutiny and opposition due to concerns about the increased occurrence of antibiotic-resistant bacteria. Alternative solutions are being sought, and plants of Lamiaceae may provide an alternative to synthetic antibiotics in animal nutrition. In this study, we extracted essential oil from Monarda didyma, a member of the Lamiaceae family. We examined the chemical composition of the essential oil and then evaluated the antibacterial, antioxidant, and anti-inflammatory activities of M. didyma essential oil and its main compounds in vitro. We then evaluated the effectiveness of M. didyma essential oil in regard to growth performance, feed efficiency, and mortality in both mice and broilers. Carvacrol (49.03%) was the dominant compound in the essential oil extracts. M. didyma essential oil demonstrated antibacterial properties against Escherichia coli (MIC = 87 µg·mL−1), Staphylococcus aureus (MIC = 47 µg·mL−1), and Clostridium perfringens (MIC = 35 µg·mL−1). Supplementing the diet of mice with essential oil at a concentration of 0.1% significantly increased body weight (+5.4%) and feed efficiency (+18.85%). In broilers, M. didyma essential oil significantly improved body weight gain (2.64%). Our results suggest that adding M. didyma essential oil to the diet of broilers offers a potential substitute for antibiotic growth promoters.


Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1941
Author(s):  
Igor V. Popov ◽  
Ammar Algburi ◽  
Evgeniya V. Prazdnova ◽  
Maria S. Mazanko ◽  
Vladimir Elisashvili ◽  
...  

One of the main problems in the poultry industry is the search for a viable replacement for antibiotic growth promoters. This issue requires a “one health” approach because the uncontrolled use of antibiotics in poultry can lead to the development of antimicrobial resistance, which is a concern not only in animals, but for humans as well. One of the promising ways to overcome this challenge is found in probiotics due to their wide range of features and mechanisms of action for health promotion. Moreover, spore-forming probiotics are suitable for use in the poultry industry because of their unique ability, encapsulation, granting them protection from the harshest conditions and resulting in improved availability for hosts’ organisms. This review summarizes the information on gastrointestinal tract microbiota of poultry and their interaction with commensal and probiotic spore-forming bacteria. One of the most important topics of this review is the absence of uniformity in spore-forming probiotic trials in poultry. In our opinion, this problem can be solved by the creation of standards and checklists for these kinds of trials such as those used for pre-clinical and clinical trials in human medicine. Last but not least, this review covers problems and challenges related to spore-forming probiotic manufacturing.


Author(s):  
Raoul Emeric Guetiya Wadoum ◽  
Fonteh Anyangwe Florence ◽  
Kaktcham Pierre Marie ◽  
Ulrich Landry Bemmo Kamdem ◽  
Chancel Hector Momo Kenfack ◽  
...  

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Vinsa Cantya Prakasita

Antibiotic growth promoters (AGP) are widely used in animal feed for feed efficiency, stimulate growth, productivity and minimize mortality by preventing infection, but now its use has been officially banned by the government. As a result of the ban, many farmers or animal feed producer seek solutions in various ways such as the addition of herbs, probiotics, and a combination of both, but there are still few reports on the role of herbs, probiotics and a combination of both for alternative substitutes for AGP. This study aims to determine the role of herbs in the growth of probiotics. Herbs used ginger, turmeric, galingale, wild ginger, and temuireng, while the probiotics used are Bifidobacterium longum, B. bifidum, Bacillus sp., and Saccharomyces cereviciae. The benefits of herbs in supporting probiotics were tested using the disc diffusion method. Chloramphenicol disc ware used as control positive. Observation and measurement of the growth zone of probiotics were carried out after incubation. The results of this study prove that herbs do not inhibit the growth of probiotics. Herbal content can be a prebiotic candidate that can support the growth of probiotics. The combination of herbal-probiotics can potentially be an AGP substitute in animal feed.


2016 ◽  
Vol 2016 ◽  
pp. 1-15 ◽  
Author(s):  
J. M. Diaz Carrasco ◽  
L. M. Redondo ◽  
E. A. Redondo ◽  
J. E. Dominguez ◽  
A. P. Chacana ◽  
...  

Necrotic enteritis (NE) is an important concern in poultry industry since it causes economic losses, increased mortality, reduction of bird welfare, and contamination of chicken products for human consumption. For decades, the use of in-feed antimicrobial growth promoters (AGPs) has been the main strategy to control intestinal pathogens includingClostridium perfringens(CP), the causative agent of NE. However, the use of AGPs in animal diet has been linked to the emergence and transmission of antimicrobial resistance through food-borne microorganisms, which has led to the ban of AGPs in many countries. This scenario has challenged the poultry industry to search for safer alternative products in order to prevent NE. In this context, the utilization of natural plant extracts with antimicrobial properties appears as a promising and feasible tool to control NE in chicken. In this paper, we review the scientific studies analyzing the potential of plant extracts as alternative feed additives to reduce NE in poultry, with focus on two types of plant products that arise as promising candidates: tannins and essential oils. Some of these products showed antimicrobial activity against CP and coccidiain vitroandin vivoand are able to increase productive performance, emulating the bioactive properties of AGPs.


2020 ◽  
Vol 66 (4) ◽  
pp. 2739-2750
Author(s):  
Amna Abuidris ◽  
Saied Abdelaziz ◽  
Nehal Roshdy ◽  
Marwa Issa

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