Thunbergia laurifolia Aqueous Leaf Extract Ameliorates Paraquat-Induced Kidney Injury by Regulating NADPH Oxidase in Rats

2021 ◽  
Author(s):  
Sarawoot Palipoch ◽  
Chuchard Punsawad ◽  
Phanit Koomhin ◽  
Wasinee Poonsawat
Keyword(s):  
Nadph Oxidase ◽  
Leaf Extract ◽  
Kidney Injury ◽  
Aqueous Leaf Extract ◽  
Thunbergia Laurifolia

scholarly journals Erratum for “Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats”

2021 ◽  
Vol 18 (5) ◽  
pp. 1149
Author(s):  
Sarawoot Palipoch ◽  
Phanit Koomhin ◽  
Chuchard Punsawad ◽  
Prasit Suwannalert
Keyword(s):  
Liver Injury ◽  
Nadph Oxidase ◽  
Normal Saline ◽  
Leaf Extract ◽  
Interleukin 1 ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
High Dose ◽  
Alcoholic Liver Injury ◽  
Blood Biochemical ◽  
Aqueous Leaf Extract

Purpose: To investigate the antioxidant and anti-inflammatory effects of aqueous leaf extract of T. laurifolia against alcoholic liver injury in rats. Methods: Male Wistar rats were administered either normal saline, ethanol (EtOH), normal saline with low or high dose T. laurifolia leaf extract (TL-LD or TL-HD), EtOH with TL-LD or EtOH with TL-HD. Blood biochemical indices: hepatic malondialdehyde (MDA) levels, liver histopathology, hepatic cytochrome P450 2E1 (CYP2E1), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and proinflammatory cytokines, including interleukin 1 beta (IL-1β) and tumor necrotic factor alpha (TNF-α) mRNA expressions, were determined using standard methods. Results: The leaf extract of T. Laurifolia decreased hepatic MDA levels, improved liver pathology and down-regulated mRNA expressions of CYP2E1, NADPH oxidase and pro-inflammatory cytokinesin ethanol-treated rats. Conclusion: These results demonstrate that aqueous extract of T. Laurifolia exerts hepatoprotective effect against alcoholic liver injury through a mechanism involving inhibition of oxidative stress and inflammation.

scholarly journals Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats

2021 ◽  
Vol 18 (4) ◽  
pp. 823-828
Author(s):  
Sarawoot Palipoch ◽  
Phanit Koomhin ◽  
Chuchard Punsawad ◽  
Prasit Suwannalert
Keyword(s):  
Liver Injury ◽  
Nadph Oxidase ◽  
Normal Saline ◽  
Leaf Extract ◽  
Interleukin 1 ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
High Dose ◽  
Alcoholic Liver Injury ◽  
Blood Biochemical ◽  
Aqueous Leaf Extract

Purpose: To investigate the antioxidant and anti-inflammatory effects of aqueous leaf extract of T. laurifolia against alcoholic liver injury in rats. Methods: Male Wistar rats were administered either normal saline, ethanol (EtOH), normal saline with low or high dose T. laurifolia leaf extract (TL-LD or TL-HD), EtOH with TL-LD or EtOH with TL-HD. Blood biochemical indices: hepatic malondialdehyde (MDA) levels, liver histopathology, hepatic cytochrome P450 2E1 (CYP2E1), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and pro-inflammatory cytokines, including interleukin 1 beta (IL-1β) and tumor necrotic factor alpha (TNF-α) mRNA expressions, were determined using standard methods. Results: The leaf extract of T. Laurifolia decreased hepatic MDA levels, improved liver pathology and down-regulated mRNA expressions of CYP2E1, NADPH oxidase and pro-inflammatory cytokinesin ethanol-treated rats. Conclusion: These results demonstrate that aqueous extract of T. Laurifolia exerts hepatoprotective effect against alcoholic liver injury through a mechanism involving inhibition of oxidative stress and inflammation.

Cytoprotective and antiadhesive effects of aqueous leaf extract from Orthosiphon aristatus against uropathogenic E. coli

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381 ◽  
Author(s):  
S Sarshar ◽  
MR Asadi Karam ◽  
M Habibi ◽  
S Bouzari ◽  
X Qin ◽  
...  
Keyword(s):  
Leaf Extract ◽  
E Coli ◽  
Aqueous Leaf Extract

Insecticidal Activities of the Leaf Extract of the Invasive Alien Plant, Chromolaena odorata (L.) (Asteraceae) Against Macrotermes species (Termites)

2019 ◽  
Vol 35 (1) ◽  
pp. 145-153
Author(s):  
O. Uyi, ◽  
I.G. Amolo ◽  
A.D. Adetimehin
Keyword(s):  
Leaf Extract ◽  
Insect Pests ◽  
Chromolaena Odorata ◽  
Leaf Extracts ◽  
Alien Plant ◽  
Biological Efficacy ◽  
Invasive Alien Plant ◽  
Impregnation Technique ◽  
Aqueous Leaf Extract ◽  
Worker Caste

Several studies have demonstrated the biological efficacy of leaf, stem and root powders or extracts of Chromolaena odorata (L.) King and Robinson against insect pests but those that are focused on the biological efficacy of aqueous leaf extracts against Macrotermes species are scanty. Current management of termites with synthetic insecticides is being discouraged due to human and environmental hazards. Therefore, the insecticidal effectiveness of aqueous leaf extract C. odorata against Macrotermes species was investigated. Five concentrations (0, 2.5, 5.0, 7.5 and 10.0% (w/v)) of the aqueous extract of C. odorata plant were evaluated for repellency and toxicity on the worker caste of Macrotermes species following standard procedures. The filter paper impregnation technique was used for the bioassay. Percentage repellency was monitored for 30 minutes and mortality recorded at 12, 24 and 36 hours post exposure. The leaf extract of C. odorata significantly repelled 95% of Macrotermes species at the highest concentration of 10% (w/v) after 30 minutes post treatment exposure. Mortality of Macrotermes species was independent of treatment concentration, but dependent on duration of exposure. All treatment concentrations of aqueous leaf extract of C. odorata caused significant mortality against Macrotermes species ranging between 94% and 98% compared to the control; indicating very great potential for adoption and use in the management of Macrotermes species.

Green Synthesis of Silver Nanoparticles by Allamanda cathartica L. Leaf Extract and Evaluation for Antimicrobial Activity

2013 ◽  
Vol 6 (4) ◽  
pp. 2260-2268
Author(s):  
M. Linga Rao ◽  
Bhumi G ◽  
Savithramma N
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Leaf Extract ◽  
Fusarium Species ◽  
Inhibition Zone ◽  
Fungal Species ◽  
Green Technology ◽  
Metallic Silver ◽  
Synthesis Of Nanoparticles ◽  
Aqueous Leaf Extract

Silver nanoparticles (SNPs) exhibit tremendous applications in medicine as antimicrobial agent.  The use of different parts of plants for the synthesis of nanoparticles is considered as a green technology as it does not involve any harmful chemicals.  In the present study, we report a rapid biosynthesis of silver nanoparticles from aqueous leaf extract of medicinal plant Allamanda cathartica.  The active phytochemicals present in the plant were responsible for the quick reduction of silver ion to metallic silver nanoparticles. The reduced silver nanoparticles were characterized by using UV-Vis spectrophotometry, Scanning Electron Microscope (SEM), Energy Dispersive Analysis of X-ray (EDAX) and Atomic Force Microscopy (AFM).  The spherical shaped silver nanoparticles were observed and it was found to 19-40 nm range of size.  These phytosynthesized SNPs were tested for their antimicrobial activity and it analyzed by measuring the inhibitory zone. A. cathartica aqueous leaf extract of SNPs showed highest toxicity to Pseudomonas followed by Klebsiella, Bacillus and E. coli and lowest toxicity towards Proteus. In fungal species, highest inhibition zone was noted against Rhizopus followed by Curvularia, Aspergillus flavus and Aspergillus niger and minimum inhibition zone was observed against Fusarium species.  These results suggest a promising potential of Indian plant-based green chemistry for production of SNPs for biomedical and nanotechnology applications.

Synthesis and characterization of TiO2 NPs by aqueous leaf extract of Coleus aromaticus and assess their antibacterial, larvicidal, and anticancer potential

2021 ◽  
pp. 111335
Author(s):  
Mathiyazhagan Narayanan ◽  
Paramasivam Vigneshwari ◽  
Devarajan Natarajan ◽  
Sabariswaran Kandasamy ◽  
Mishal Alsehli ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Synthesis And Characterization ◽  
Tio2 Nps ◽  
Aqueous Leaf Extract ◽  
Coleus Aromaticus
Sign in / Sign up

Export Citation Format

Share Document