Toward a Biomarker of Addiction Relapse Risk: Heart Rate Variability Predicts Subsequent Alcohol Use in Individuals in Early Recovery from Alcohol Use Disorder

2021 ◽  
Author(s):  
David Eddie ◽  
Sarah Wieman ◽  
Agata Pietrzak ◽  
Xiadi Zhai
2017 ◽  
Vol 13 ◽  
pp. 68-76 ◽  
Author(s):  
Carina Bichler ◽  
Martin Niedermeier ◽  
Anika Frühauf ◽  
Nicole Längle ◽  
W. Wolfgang Fleischhacker ◽  
...  

2020 ◽  
Author(s):  
Sihong Liu ◽  
Assaf Oshri ◽  
Erinn Duprey

Background and Objectives. Young adults with childhood maltreatment (CM) histories are particularly vulnerable to depressive symptoms and alcohol use problems. Research suggest that maltreated youth may misuse alcohol in part to alleviate depressive symptoms. However, many youths with depressive symptoms exercise self-control and abstain from heavy alcohol use. The present study aimed to examine the influence of heart rate variability reactivity (HRV-R), a psychophysiological biomarker of self-regulation, in the indirect link between CM and alcohol use problems via depressive symptoms among low socioeconomic-status rural young adults. Methods. Two waves of data were collected from a community sample of 225 low socioeconomic-status non-metropolitan young adults (Mage = 21.56, 52.9% female). HRV data were obtained with an electrocardiogram during a social stress task. CM was assessed through the Childhood Trauma Questionnaire. Alcohol use problems were measured using the Alcohol Use Disorders Identification Test. Results. The indirect effect of CM on alcohol use problems via elevated depressive symptoms was positive and significant (α*β = .159, p < .001). Self-regulation indicated by high HRV-R (i.e., vagal withdrawal) was found to significantly buffer the link between depressive symptoms and alcohol use problems (β = .193, p = .022). Discussion and Conclusions. Adequate self-regulation capacities can protect maltreated youths from self-medicating alcohol use problems. Scientific Significance. This study will advance researchers’ understanding of the development of alcohol use problems through unwrapping the risk and protective mechanisms underlying the association between young adults’ early life stress and alcohol use behaviors.


2008 ◽  
Vol 7 (5-1) ◽  
pp. 122-127
Author(s):  
D. A. Doshchannikov ◽  
T. V. Mokina

The purpose of present research is to estimate the influence of ischemic stroke on changes of clinical and instrumental parameters in patients with chronic heart failure (CHF) depending on expressiveness of neurologic deficiency. We supervised 103 patients with CHF, among them 71 patients with stroke. In all the patients twice heart rate variability and echocardiography were carried out. To determine CHF FC we used an estimation scale of a clinical condition (SHOCKS by Mareev, 2000). After 6 months all the patients were divided into 2 groups depending on expressiveness of neurological deficieny. Significant deterioration of heart rate variability (HRV) parameters in the group of patients with expressed neurological deficiency was revealed. Also in this group increase of end diastolic volume, end systolic volume and deterioration of diastolic function was revealed. 6 months after stroke in patients with CHF with expressed neurological deficiency reduction of parameters of HRV, progressiveness of hyperactivity of sympathetic adrenal system, deterioration of morphological-functional parameters of left ventrical was revealed.


2010 ◽  
Vol 35 (S1) ◽  
pp. 439-446 ◽  
Author(s):  
Goncalo V. Mendonca ◽  
Kevin S. Heffernan ◽  
Lindy Rossow ◽  
Myriam Guerra ◽  
Fernando D. Pereira ◽  
...  

Women demonstrate greater RR interval variability than men of similar age. Enhanced parasympathetic input into cardiac regulation appears to be not only greater in women, but also protective during periods of cardiac stress. Even though women may have a more favorable autonomic profile after exercise, little research has been conducted on this issue. This study was designed to examine the cardiac autonomic response, in both male and female participants, during the early recovery from supramaximal exercise. Twenty-five individuals, aged 20 to 33 years (13 males and 12 females), performed a 30-s Wingate test. Beat-to-beat RR series were recorded before and 5 min after exercise, with the participants in the supine position and under paced breathing. Linear (spectral analysis) and nonlinear analyses (detrended fluctuation analysis (DFA)) were performed on the same RR series. At rest, women presented lower raw low frequency (LF) power and higher normalized high frequency (HF) power. Under these conditions, the LF/HF ratio of women was also lower than that of men (p < 0.05), but there were no differences in the short-term scaling exponent (α1). Even though both sexes showed a significant modification in linear and nonlinear measures of heart rate variability (HRV) (p < 0.05), women had a greater change in LF/HF ratio and α1 than men from rest to recovery. This study demonstrates that the cardiac autonomic function of women is more affected by supramaximal exercise than that of men. Additionally, DFA did not provide additional information about sexual dimorphisms, compared with conventional spectral HRV techniques.


2015 ◽  
Author(s):  
Renee Graham

<p>Women with Alcohol Use Disorder (AUD) have a higher risk of chronic illness and a mortality rate that is 50 to 100% greater than men’s (National Institute on Alcohol Abuse and Alcoholism, 2008). Lifestyle changes in the recovery from AUD include adopting behaviors that foster health and identifying women’s barriers to health promotion behavior is important to fostering a healthy lifestyle. The purpose of this study was to explore perceived barriers to health promotion behavior of women in early recovery from AUD. Participants were women (N = 50) who attended 12-step recovery meetings for alcoholism, of which: 86% were 26 to 57 years old; 72% had greater than a ten year history of consumption; 80% had less than six months of sobriety; 50% had relapsed three or more times. Results indicated some women perceived certain barriers to be very troublesome but generally barriers were only a moderate challenge. Greatest perceived barriers cited were financial aspects, fatigue, time management issues, selfefficacy concerns, and communication difficulties. Implications for practice include conducting research on the nature of the most concerning barriers and the impact that severity of disease, culture, ethnicity, or demographics has on these barriers. Increasing awareness of women’s barriers, lobbying and supporting policies and systems processes that reduce barriers and support access to preventative services, early intervention, gender specific programs, and addressing patient-specific barriers will improve outcomes. Utilizing a comprehensive approach will have the greatest impact on the health promotion behaviors of individuals and the population health status of women with AUD.</p>


2020 ◽  
Author(s):  
Sihong Liu ◽  
Assaf Oshri ◽  
Erinn Duprey

Background and Objectives. Young adults with childhood maltreatment (CM) histories are particularly vulnerable to depressive symptoms and alcohol use problems. Research suggest that maltreated youth may misuse alcohol in part to alleviate depressive symptoms. However, many youths with depressive symptoms exercise self-control and abstain from heavy alcohol use. The present study aimed to examine the influence of heart rate variability reactivity (HRV-R), a psychophysiological biomarker of self-regulation, in the indirect link between CM and alcohol use problems via depressive symptoms among low socioeconomic-status rural young adults. Methods. Two waves of data were collected from a community sample of 225 low socioeconomic-status non-metropolitan young adults (Mage = 21.56, 52.9% female). HRV data were obtained with an electrocardiogram during a social stress task. CM was assessed through the Childhood Trauma Questionnaire. Alcohol use problems were measured using the Alcohol Use Disorders Identification Test. Results. The indirect effect of CM on alcohol use problems via elevated depressive symptoms was positive and significant (α*β = .159, p &lt; .001). Self-regulation indicated by high HRV-R (i.e., vagal withdrawal) was found to significantly buffer the link between depressive symptoms and alcohol use problems (β = .193, p = .022). Discussion and Conclusions. Adequate self-regulation capacities can protect maltreated youths from self-medicating alcohol use problems. Scientific Significance. This study will advance researchers’ understanding of the development of alcohol use problems through unwrapping the risk and protective mechanisms underlying the association between young adults’ early life stress and alcohol use behaviors.


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