Extended Human Papilloma Virus Genotyping for Risk Assessment of Cervical Intraepithelial Neoplasia Grade 2 or Worse in a Cohort Study

2021 ◽  
Author(s):  
Xiao Li ◽  
Xuan Rao ◽  
Weiguo Lu ◽  
Xing Xie ◽  
Xinyu Wang
Keyword(s):  
Risk Assessment ◽  
Cohort Study ◽  
Human Papilloma Virus ◽  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
Cervical Intraepithelial Neoplasia Grade ◽  
Papilloma Virus

Performance of Pap smear and human papilloma virus testing in the follow-up of women with cervical intraepithelial neoplasia grade 1 managed conservatively

2006 ◽  
Vol 85 (4) ◽  
pp. 444-450 ◽  
Author(s):  
André Luis Ferreira Santos ◽  
Sophie Françoise Mauricette Derchain ◽  
Luis Otávio Sarian ◽  
Marcos Roberto Martins ◽  
Sirlei Siani Morais ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Cervical Intraepithelial Neoplasia ◽  
Pap Smear ◽  
Intraepithelial Neoplasia ◽  
Cervical Intraepithelial Neoplasia Grade ◽  
Papilloma Virus ◽  
Virus Testing

scholarly journals A direct comparison of four high risk human papilloma virus tests versus the cobas test for detecting cervical intraepithelial neoplasia and cervical cancer

2018 ◽  
Author(s):  
Peng Xue ◽  
Li-Li Gao ◽  
Jian Yin ◽  
Li-Li Han ◽  
Jing Zhao ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Cervical Intraepithelial Neoplasia ◽  
Clinical Decision Making ◽  
Intraepithelial Neoplasia ◽  
Hpv Infection ◽  
Cervical Intraepithelial Neoplasia Grade ◽  
Papilloma Virus ◽  
Clinical Sensitivity ◽  
Detection Techniques ◽  
Hpv Genotyping

ABSTRACTThis study is to evaluate performances and genotyping capabilities of four human papilloma virus (HR-HPV) tests based on real-time polymerase chain reaction (PCR) technology platforms compared with the cobas test. Discordant results were further analyzed using INNO-LiPA HPV genotyping test, the gold standard laboratory test to determine presence and type of HPV infection. Over 200 samples from Hospital patients were collected and analyzed using five HR-HPV tests. Women with positive test results were referred directly to colposcopy. If a positive result was returned, biopsies were administered for pathological classification. Clinical performances and genotyping capabilities between the four HR-HPV and cobas tests were compared and contrasted. High levels of agreement were observed, though all HR-HPV tests presented discrepancies compared with the cobas test. Cervical intraepithelial neoplasia Grade 2 or higher lesions (CIN2+) was set as the threshold, and all five tests performed with equally high sensitivity. Lower levels of specificity were observed across all five tests. Results suggest the four HR-HPV tests analyzed are as effective as the cobas test in genotyping capacities and diagnosing CIN. Therefore, these test kits should be used for HPV screening, especially in developing nations because they are cost effective and reliable. Minor discrepancies between tests are generally unavoidable though this may add complexity to the clinical decision-making process. As such, we recommend that efforts be made to standardize HPV genotyping tests as well as to optimize clinical sensitivity and specificity. Focusing on these issues will drive the development of HPV detection techniques, therefore save lives.

Association of cervical intraepithelial neoplasia 2 and 3 regression by human papilloma Virus Serotype

2012 ◽  
Vol 125 ◽  
pp. S50-S51
Author(s):  
K. Harris ◽  
T. Kiet ◽  
G. Sawaya ◽  
S. Wilczynski ◽  
K. Smith-McCune ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
Papilloma Virus ◽  
Virus Serotype

Human papilloma virus testing in patient follow-up post cone biopsy due to high-grade cervical intraepithelial neoplasia

2003 ◽  
Vol 88 (3) ◽  
pp. 345-350 ◽  
Author(s):  
Benny Almog ◽  
Ronni Gamzu ◽  
Michael J Kuperminc ◽  
Ishai Levin ◽  
Ofer Fainaru ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
High Grade ◽  
Papilloma Virus ◽  
Cone Biopsy ◽  
Virus Testing

scholarly journals The risk of cervical cancer after cervical intraepithelial neoplasia grade 3: A population-based cohort study with 80,442 women

2020 ◽  
Vol 157 (1) ◽  
pp. 195-201
Author(s):  
Diede L. Loopik ◽  
Joanna IntHout ◽  
Renée M.F. Ebisch ◽  
Willem J.G. Melchers ◽  
Leon F.A.G. Massuger ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cohort Study ◽  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
Population Based ◽  
Cervical Intraepithelial Neoplasia Grade ◽  
Grade 3
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