Perceptual Learning Versus Part-Time Patching for Deprivation Amblyopia in Limbal Dermoid Children After Keratoplasty: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Jing Zhong ◽  
Wei Wang ◽  
Yiyao Wang ◽  
Xiaoqing Hu ◽  
Lei Feng ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Perceptual Learning ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Part Time ◽  
Limbal Dermoid

Effect of a plantar perceptual learning task on walking stability in the elderly: a randomized controlled trial

2013 ◽  
Vol 27 (7) ◽  
pp. 608-615 ◽  
Author(s):  
Hideki Nakano ◽  
Makoto Nozaki ◽  
Kozo Ueta ◽  
Michihiro Osumi ◽  
Seigou Kawami ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Perceptual Learning ◽  
Controlled Trial ◽  
The Elderly ◽  
Learning Task ◽  
Randomized Controlled

scholarly journals Health-related effects of early part-time sick leave due to musculoskeletal disorders: a randomized controlled trial

2012 ◽  
Vol 39 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Rahman Shiri ◽  
Johanna Kausto ◽  
Kari-Pekka Martimo ◽  
Leena Kaila-Kangas ◽  
Esa-Pekka Takala ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Sick Leave ◽  
Musculoskeletal Disorders ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Health Related ◽  
Part Time

scholarly journals Return to work after early part-time sick leave due to musculoskeletal disorders: a randomized controlled trial

2011 ◽  
Vol 38 (2) ◽  
pp. 134-143 ◽  
Author(s):  
Eira Viikari-Juntura ◽  
Johanna Kausto ◽  
Rahman Shiri ◽  
Leena Kaila-Kangas ◽  
Esa-Pekka Takala ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Sick Leave ◽  
Return To Work ◽  
Musculoskeletal Disorders ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Part Time

Vacuum-formed retainer versus bonded retainer for dental stabilization in the mandible—a randomized controlled trial. Part I: retentive capacity 6 and 18 months after orthodontic treatment

2019 ◽  
Vol 42 (5) ◽  
pp. 551-558 ◽  
Author(s):  
Anke Krämer ◽  
Mats Sjöström ◽  
Mats Hallman ◽  
Ingalill Feldmann
Keyword(s):  
Randomized Controlled Trial ◽  
Orthodontic Treatment ◽  
Controlled Trial ◽  
Three Dimensional ◽  
Retention Capacity ◽  
Randomized Controlled ◽  
Irregularity Index ◽  
Parallel Group ◽  
Part Time ◽  
Three Dimensional Models

Summary Background Evidence concerning the most appropriate retention strategy after orthodontic treatment is still inconclusive. Objective This trial compares the retentive capacity of vacuum-formed Essix C-retainers (VFR) and bonded cuspid-to-cuspid retainers (CTC) in the mandible 6 and 18 months after orthodontic treatment. Trial design A single-centre two-arm parallel-group randomized controlled trial. Methods This study included 104 adolescent patients, computer-generated randomized with sequentially numbered, opaque, and sealed envelopes into two groups and stratified by gender (52 females and 52 males). The patients were treated with fixed appliances with and without tooth extractions in both jaws and were ready for debond. In the intervention arm, patients received a VFR (n = 52); in the active comparator arm, patients received a CTC (n = 52). Dental casts were obtained at debond (T1), after 6 months (T2), and after 18 months (T3). The casts were digitized. The retentive capacity was evaluated on digital three-dimensional models using Little’s Irregularity Index (LII), overbite, overjet, arch length, and intermolar and intercanine width. Results Baseline values were similar for both groups. Statistically significant increases were noted in LII and overbite, mainly between T1 and T2, but also between T1 and T3 in the VFR group (LII = 0.52 mm, P < 0.001, overbite = 0.51 mm, P < 0.001) and in the CTC group (LII = 0.45 mm P < 0.001, overbite = 0.36 mm, P < 0.001). There were no significant differences between groups. Overjet showed small variations during the observation periods but was overall stable within and between groups after 18 months. Arch length decreased slightly in both groups after 6 and 18 months. Intermolar and intercanine widths remained stable after debond. Limitations Patients, operator, and outcome assessor could not be blinded due to the study design. Conclusions VFR and CTC have the same retention capacity in the mandible after 6 and 18 months. Relapse mainly occurs during the first 6 months of retention, but the post-treatment changes are generally small. Shorter VFRs in the mandible do not cause negative vertical effects. Part-time wear regimen is not associated with increased relapse. Trial registration NCT03070444.

Treatment Fidelity Procedures for an Aphasia Intervention Within a Randomized Controlled Trial: Design, Feasibility, and Results

2020 ◽  
Vol 29 (1S) ◽  
pp. 412-424
Author(s):  
Elissa L. Conlon ◽  
Emily J. Braun ◽  
Edna M. Babbitt ◽  
Leora R. Cherney
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Treatment Protocol ◽  
Treatment Fidelity ◽  
Protocol Adherence ◽  
Study Condition ◽  
Randomized Controlled ◽  
Aphasia Therapy ◽  
Percent Accuracy ◽  
Over Time

Purpose This study reports on the treatment fidelity procedures implemented during a 5-year randomized controlled trial comparing intensive and distributed comprehensive aphasia therapy. Specifically, the results of 1 treatment, verb network strengthening treatment (VNeST), are examined. Method Eight participants were recruited for each of 7 consecutive cohorts for a total of 56 participants. Participants completed 60 hr of aphasia therapy, including 15 hr of VNeST. Two experienced speech-language pathologists delivered the treatment. To promote treatment fidelity, the study team developed a detailed manual of procedures and fidelity checklists, completed role plays to standardize treatment administration, and video-recorded all treatment sessions for review. To assess protocol adherence during treatment delivery, trained research assistants not involved in the treatment reviewed video recordings of a subset of randomly selected VNeST treatment sessions and completed the fidelity checklists. This process was completed for 32 participants representing 2 early cohorts and 2 later cohorts, which allowed for measurement of protocol adherence over time. Percent accuracy of protocol adherence was calculated across clinicians, cohorts, and study condition (intensive vs. distributed therapy). Results The fidelity procedures were sufficient to promote and verify a high level of adherence to the treatment protocol across clinicians, cohorts, and study condition. Conclusion Treatment fidelity strategies and monitoring are feasible when incorporated into the study design. Treatment fidelity monitoring should be completed at regular intervals during the course of a study to ensure that high levels of protocol adherence are maintained over time and across conditions.

Phonomotor Versus Semantic Feature Analysis Treatment for Anomia in 58 Persons With Aphasia: A Randomized Controlled Trial

2019 ◽  
Vol 62 (12) ◽  
pp. 4464-4482 ◽  
Author(s):  
Diane L. Kendall ◽  
Megan Oelke Moldestad ◽  
Wesley Allen ◽  
Janaki Torrence ◽  
Stephen E. Nadeau
Keyword(s):  
Randomized Controlled Trial ◽  
Response Latency ◽  
Controlled Trial ◽  
Semantic Knowledge ◽  
Semantic Feature ◽  
Feature Analysis ◽  
Group Differences ◽  
Randomized Controlled ◽  
Confrontation Naming ◽  
Semantic Feature Analysis

Purpose The ultimate goal of anomia treatment should be to achieve gains in exemplars trained in the therapy session, as well as generalization to untrained exemplars and contexts. The purpose of this study was to test the efficacy of phonomotor treatment, a treatment focusing on enhancement of phonological sequence knowledge, against semantic feature analysis (SFA), a lexical-semantic therapy that focuses on enhancement of semantic knowledge and is well known and commonly used to treat anomia in aphasia. Method In a between-groups randomized controlled trial, 58 persons with aphasia characterized by anomia and phonological dysfunction were randomized to receive 56–60 hr of intensively delivered treatment over 6 weeks with testing pretreatment, posttreatment, and 3 months posttreatment termination. Results There was no significant between-groups difference on the primary outcome measure (untrained nouns phonologically and semantically unrelated to each treatment) at 3 months posttreatment. Significant within-group immediately posttreatment acquisition effects for confrontation naming and response latency were observed for both groups. Treatment-specific generalization effects for confrontation naming were observed for both groups immediately and 3 months posttreatment; a significant decrease in response latency was observed at both time points for the SFA group only. Finally, significant within-group differences on the Comprehensive Aphasia Test–Disability Questionnaire ( Swinburn, Porter, & Howard, 2004 ) were observed both immediately and 3 months posttreatment for the SFA group, and significant within-group differences on the Functional Outcome Questionnaire ( Glueckauf et al., 2003 ) were found for both treatment groups 3 months posttreatment. Discussion Our results are consistent with those of prior studies that have shown that SFA treatment and phonomotor treatment generalize to untrained words that share features (semantic or phonological sequence, respectively) with the training set. However, they show that there is no significant generalization to untrained words that do not share semantic features or phonological sequence features.

Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial

2001 ◽  
Vol 26 (1) ◽  
pp. 67-71 ◽  
Author(s):  
S. A. Ahmadi-Abhari ◽  
S. Akhondzadeh ◽  
S. M. Assadi ◽  
O. L. Shabestari ◽  
Z. M. Farzanehgan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Side Effects ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled
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