Design Rules for Time of Flight Positron Emission Tomography (ToF-PET) Heterostructure Radiation Detectors

2021 ◽  
Author(s):  
Philip Krause ◽  
Edith Rogers ◽  
Muhammad Danang Birowosuto ◽  
Qibing Pei ◽  
Etiennette Auffray ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Time Of Flight ◽  
Radiation Detectors ◽  
Emission Tomography ◽  
Design Rules ◽  
Positron Emission ◽  
Tof Pet

scholarly journals Photo-Detectors for Time of Flight Positron Emission Tomography (ToF-PET)

Sensors ◽  
2010 ◽  
Vol 10 (11) ◽  
pp. 10484-10505 ◽  
Author(s):  
Virginia Ch. Spanoudaki ◽  
Craig S. Levin
Keyword(s):  
Positron Emission Tomography ◽  
Time Of Flight ◽  
Emission Tomography ◽  
Positron Emission ◽  
Photo Detectors ◽  
Tof Pet

scholarly journals Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Vanessa Nadig ◽  
David Schug ◽  
Bjoern Weissler ◽  
Volkmar Schulz
Keyword(s):  
Positron Emission Tomography ◽  
Integrated Circuits ◽  
Energy Resolution ◽  
Time Of Flight ◽  
Emission Tomography ◽  
Silicon Photomultipliers ◽  
Arrival Times ◽  
Positron Emission ◽  
The Difference ◽  
Tof Pet

Abstract Background Aiming to measure the difference in arrival times of two coincident γ-photons with an accuracy in the order of 200ps, time-of-flight positron emission tomography systems commonly employ silicon photomultipliers (SiPMs) and high-resolution digitization electronics, application specific integrated circuits (ASICs). This work evaluates the performance of the TOFPET2 ASIC, released by PETsys Electronics S.A. in 2017, dependent on its configuration parameters in multi-channel coincidence measurements. Methods SiPM arrays fabricated by different vendors (KETEK, SensL, Hamamatsu, Broadcom) were tested in combination with the ASIC. Scintillator arrays featuring different reflector designs and different configurations of the TOFPET2 ASIC software parameters were evaluated. The benchtop setup used is provided with the TOFPET2 ASIC evaluation kit by PETsys Electronics S.A. Results Compared to existing studies featuring the TOFPET2 ASIC, multi-channel performance results dependent on a larger set of ASIC configuration parameters were obtained that have not been reported to this extend so far. The ASIC shows promising CRTs down to 219.9 ps in combination with two Hamamatsu S14161-3050-HS-08 SiPM arrays (128 channels read out, energy resolution 13.08%) and 216.1 ps in combination with two Broadcom AFBR-S4N44P643S SiPM arrays (32 channels read out, energy resolution 9.46%). The length of the trigger delay of the dark count suppression scheme has an impact on the ASIC performance and can be configured to further improve the coincidence resolution time. The integrator gain configuration has been investigated and allows an absolute improvement of the energy resolution by up to 1% at the cost of the linearity of the energy spectrum. Conclusion Measuring up to the time-of-flight performance of state-of-the-art positron emission tomography (ToF-PET) systems while providing a uniform and stable readout for multiple channels at the same time, the TOFPET2 ASIC is treated as promising candidate for the integration in future ToF-PET systems.

scholarly journals Time-Based Readout of a Silicon Photomultiplier (SiPM) for Time of Flight Positron Emission Tomography (TOF-PET)

2011 ◽  
Vol 58 (3) ◽  
pp. 597-604 ◽  
Author(s):  
F. Powolny ◽  
E. Auffray ◽  
S. E. Brunner ◽  
E. Garutti ◽  
M. Goettlich ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Time Of Flight ◽  
Emission Tomography ◽  
Silicon Photomultiplier ◽  
Positron Emission ◽  
Tof Pet

scholarly journals Analytic time-of-flight positron emission tomography reconstruction: two-dimensional case

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Gengsheng L. Zeng ◽  
Ya Li ◽  
Qiu Huang
Keyword(s):  
Positron Emission Tomography ◽  
Image Reconstruction ◽  
Iterative Algorithm ◽  
Emission Tomography ◽  
Two Dimensional ◽  
Profile Function ◽  
Positron Emission ◽  
Pet Image Reconstruction ◽  
2D Filter ◽  
Tof Pet

AbstractIn a positron emission tomography (PET) scanner, the time-of-flight (TOF) information gives us rough event position along the line-of-response (LOR). Using the TOF information for PET image reconstruction is able to reduce image noise. The state-of-the-art TOF PET image reconstruction uses iterative algorithms. Analytical image reconstruction algorithm exits for TOF PET which emulates the iterative Landweber algorithm. This paper introduces such an algorithm, focusing on two-dimensional (2D) reconstruction. The proposed algorithm is in the form of backprojection filtering, in which the backprojection is performed first, and then a 2D filter is applied to the backprojected image. For the list-mode data, the backprojection is carried out in the event-by-event fashion, and a profile function may be used along the projection LOR. The 2D filter depends on the TOF timing resolution as well as the backprojection profile function. In order to emulate the iterative algorithm effects, a Fourier-domain window function is suggested. This window function has a parameter, k, which corresponds to the iteration number in an iterative algorithm.

scholarly journals Evaluation of Various Scintillator Materials in Radiation Detector Design for Positron Emission Tomography (PET)

Crystals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 869
Author(s):  
Siwei Xie ◽  
Xi Zhang ◽  
Yibin Zhang ◽  
Gaoyang Ying ◽  
Qiu Huang ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
High Performance ◽  
Radiation Detector ◽  
Experimental Studies ◽  
Light Output ◽  
Radiation Detectors ◽  
Emission Tomography ◽  
Timing Resolution ◽  
Positron Emission ◽  
Co Doped

The performance of radiation detectors used in positron-emission tomography (PET) is determined by the intrinsic properties of the scintillators, the geometry and surface treatment of the scintillator crystals and the electrical and optical characteristics of the photosensors. Experimental studies were performed to assess the timing resolution and energy resolution of detectors constructed with samples of different scintillator materials (LaBr3, CeBr3, LFS, LSO, LYSO: Ce, Ca and GAGG) that were fabricated into different shapes with various surface treatments. The saturation correction of SiPMs was applied for tested detectors based on a Tracepro simulation. Overall, we tested 28 pairs of different forms of scintillators to determine the one with the best CTR and light output. Two common high-performance silicon photomultipliers (SiPMs) provided by SensL (J-series, 6 mm) or AdvanSiD (NUV, 6 mm) were used for photodetectors. The PET detector constructed with 6 mm CeBr3 cubes achieved the best CTR with a FWHM of 74 ps. The 4 mm co-doped LYSO: Ce, Ca pyramid crystals achieved 88.1 ps FWHM CTR. The 2 mm, 4 mm and 6 mm 0.2% Ce, 0.1% Ca co-doped LYSO cubes achieved 95.6 ps, 106 ps and 129 ps FWHM CTR, respectively. The scintillator crystals with unpolished surfaces had better timing than those with polished surfaces. The timing resolution was also improved by using certain geometric factors, such as a pyramid shape, to improve light transportation in the scintillator crystals.

Sign in / Sign up

Export Citation Format

Share Document