Hazardous Use of Benzodiazepine and Z-Drugs in Psychiatric Clinics in China: An Electronic Prescription Database Study

2021 ◽  
Author(s):  
Xiaomin Xu ◽  
Jiajun Xu ◽  
Chuanwei Li ◽  
Gang Wang ◽  
Wenzhe Wang ◽  
...  
Keyword(s):  
Prescription Database ◽  
Electronic Prescription ◽  
Database Study ◽  
Hazardous Use

scholarly journals Aspects of statin prescribing in Norwegian counties with high, average and low statin consumption – an individual-level prescription database study

2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Ingeborg Hartz ◽  
Solveig Sakshaug ◽  
Kari Furu ◽  
Anders Engeland ◽  
Anne Elise Eggen ◽  
...  
Keyword(s):  
Prescription Database ◽  
Database Study ◽  
Individual Level

scholarly journals Risks and uncertainties about gabapentinoids

2021 ◽  
pp. 1-14
Author(s):  
Natalia Alzueta ◽  
◽  
Patricia García-González ◽  
Irati Irigoyen ◽  
Keyword(s):  
Respiratory Depression ◽  
Prescription Database ◽  
Low Back ◽  
Electronic Prescription ◽  
Peripheral Neuropathic Pain ◽  
The Public ◽  
Off Label ◽  
Pubmed Search ◽  
The Central Nervous System ◽  
Potential Risks

INTRODUCTION The use of gabapentinoids has increased in the recent years. Approved indications include epilepsy, peripheral neuropathic pain, diabetic neuropathy, postherpetic neuralgia and anxiety disorder. However, these drugs are widely prescribed off-label for indications such as low back pain, fibromyalgia, migraine or restless legs syndrome. Side effects associated with these drugs are common, highlighting the risk of respiratory depression when combined with other drugs that depress the central nervous system, suicidal ideation, abuse and addiction. OBJETIVE To review the evidence available on the uses of gabapentinoids (epilepsy excluded) and its associated risks. METHODS A search in Tripdatabase and Dynamed was conducted for clinical practice guidelines. In addition, a PubMed search was performed including systematic reviews, clinical trials and observational studies in order to analyze the evidence available on these drugs for their different indications. Data about the use of gabapentinoids in Navarre were obtained from the electronic prescription database of the public health system of Navarre -Osasunbidea (SNS-O). CONCLUSIONS Off-label use of gabapentinoids is not recommended due to the lack of consistent evidence available and its potential risks (sedation, dizziness or respiratory depression). Some recommendations are provided for a safe prescription of gabapentinoids.

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