Development and Validation of an UPLC-MS/MS Method for Simultaneous Determination of Fifteen Targeted Anti-Cancer Drugs in Human Plasma and Its Application in Therapeutic Drug Monitoring

2021 ◽  
Author(s):  
Guofei Li ◽  
Mingming Zhao ◽  
Limei Zhao
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Drug Monitoring ◽  
Therapeutic Drug ◽  
Cancer Drugs ◽  
Anti Cancer ◽  
Development And Validation

A simple and automated online SPE-LC-MS/MS method for simultaneous determination of olanzapine, fluoxetine and norfluoxetine in human plasma and its application in therapeutic drug monitoring

RSC Advances ◽  
2015 ◽  
Vol 5 (43) ◽  
pp. 34342-34352 ◽  
Author(s):  
Yiran Fan ◽  
Guanghu Shen ◽  
Ping Li ◽  
Xiaonan Xi ◽  
Haiting Wu ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Drug Monitoring ◽  
Sample Pretreatment ◽  
Therapeutic Drug ◽  
High Quality ◽  
Online Spe

An integration of sample pretreatment automation using online SPE technique could provide an easy to use, efficient, sensitive and high quality methods for TDM.

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