Hplc-Ms/Ms Analysis of Key Components of the Amino Acid Metabolism in the Serum of Acute Myocardial Infarction Patients

2021 ◽  
Author(s):  
Yi Cen ◽  
Hong-liu Jin ◽  
Sen-Ling Feng ◽  
Wen-Ting Zhu ◽  
Dong-Dong Jing ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Ms Analysis

scholarly journals Targeting Amino Acid Metabolism for Molecular Imaging of Inflammation Early After Myocardial Infarction

Theranostics ◽  
2016 ◽  
Vol 6 (11) ◽  
pp. 1768-1779 ◽  
Author(s):  
James T. Thackeray ◽  
Jens P. Bankstahl ◽  
Yong Wang ◽  
Kai C. Wollert ◽  
Frank M. Bengel
Keyword(s):  
Myocardial Infarction ◽  
Amino Acid ◽  
Molecular Imaging ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Greater than expected alanine aminotransferase activities in plasma and in hearts of patients with acute myocardial infarction.

1989 ◽  
Vol 35 (2) ◽  
pp. 279-283 ◽  
Author(s):  
P L Giesen ◽  
H G Peltenburg ◽  
C de Zwaan ◽  
P C Janson ◽  
J G Flendrig ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Skeletal Muscle ◽  
Acute Myocardial Infarction ◽  
Alanine Aminotransferase ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Wet Weight ◽  
The Mean ◽  
Alt Activity

Abstract Early increases in the activity of alanine aminotransferase (ALT, EC 2.6.1.2) in plasma are observed in about 7% of patients with acute myocardial infarction (AMI), of whom about half die. Some type of liver injury, secondary to AMI, could be responsible for this phenomenon. However, quantitative analysis shows that the release of ALT in most of these patients conforms to the myocardial release pattern. Moreover, extra release of hepatic aspartate aminotransferase (EC 2.6.1.1) is not observed. These findings suggest that the heart may occasionally contain a high ALT activity. This hypothesis was verified by determination of enzyme activities in 10 hearts obtained from patients who died after AMI. The mean ALT activity in these hearts, 21 (SD 12) U per gram wet weight, significantly (P less than 0.01) exceeds the value of 7.7 (SD 4.9) U/g found for seven control hearts and may reflect increased amino acid metabolism in the energy-depleted heart muscle, as described earlier for skeletal muscle.

Amino Acid Metabolism

1979 ◽  
Vol 7 (1) ◽  
pp. 261-262
Author(s):  
E. V. ROWSELL
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Effect of intravenous bicarbonate administration on postoperative amino acid metabolism

1985 ◽  
Vol 4 ◽  
pp. 141-146 ◽  
Author(s):  
K VESTERBERG ◽  
J BERGSTROM ◽  
P FURST ◽  
U LEANDER ◽  
E VINNARS
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Different sensitivity of glucose and amino acid metabolism to insulin in NIDDM

Diabetes ◽  
1993 ◽  
Vol 42 (12) ◽  
pp. 1868-1877 ◽  
Author(s):  
L. Luzi ◽  
A. S. Petrides ◽  
R. A. De Fronzo
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism
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