A Randomized Single Blind Controlled Trial of Combination Therapy (Spironolactone and Sitagliptin) in Hospitalized Adult Patients with Covid-19

2021 ◽  
Author(s):  
Kamyar Asadipooya ◽  
Farhad Abbasi ◽  
Reuben Adatorwovor ◽  
Mohammad Ali Davarpanah ◽  
Yasaman Mansoori ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Controlled Trial ◽  
Adult Patients ◽  
Single Blind

scholarly journals Randomised Comparison of the AMBU AuraOnce Laryngeal Mask and the LMA Unique Laryngeal Mask Airway in Spontaneously Breathing Adults

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Daryl Lindsay Williams ◽  
James M. Zeng ◽  
Karl D. Alexander ◽  
David T. Andrews
Keyword(s):  
Statistical Difference ◽  
Controlled Trial ◽  
Adult Patients ◽  
Laryngeal Mask ◽  
Leak Pressure ◽  
Oropharyngeal Leak Pressure ◽  
Airway Devices ◽  
Spontaneously Breathing ◽  
To Receive ◽  
Single Blind

We conducted a randomised single-blind controlled trial comparing the LMA-Unique (LMAU) and the AMBU AuraOnce (AMBU) disposable laryngeal mask in spontaneously breathing adult patients undergoing general anaesthesia. Eighty-two adult patients (ASA status I–IV) were randomly allocated to receive the LMAU or AMBU and were blinded to device selection. Patients received a standardized anesthetic and all airway devices were inserted by trained anaesthetists. Size selection was guided by manufacturer recommendations. All data were collected by a single, unblinded observer. When compared with the LMAU, the AMBU produced significantly higher airway sealing pressures (AMBU20±6; LMAU15±7 cm H2O;P=0.001). There was no statistical difference between the two devices for overall success rate, insertion time, number of adjustments, laryngeal alignment, blood-staining, and sore throat (P≥0.05). The AMBU AuraOnce disposable laryngeal mask provided a higher oropharyngeal leak pressure compared to the LMA Unique in spontaneously breathing adult patients.

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