Biosafety Evaluation of Biogas Generated From Biowaste-Fed Digester Systems

2021 ◽  
Author(s):  
Sunday Akinde ◽  
Oluwaseyi Paul Olaniyan ◽  
Omowumi Adewale ◽  
Omotayo Opemipo Oyedara ◽  
Ebenezer Idowu Ajayi ◽  
...  
Keyword(s):  
Biosafety Evaluation

BRAZILIAN GMO REGULATION: DOES IT HAVE AN ENVIRONMENTAL APPROACH?

2012 ◽  
Vol 14 (02) ◽  
pp. 1250013 ◽  
Author(s):  
DENISE GALLO PIZELLA ◽  
MARCELO PEREIRA DE SOUZA
Keyword(s):  
Decision Making ◽  
Risk Analysis ◽  
Environmental Impacts ◽  
Genetically Modified ◽  
Genetically Modified Crops ◽  
Gm Crops ◽  
Gm Crop ◽  
Institutional Issues ◽  
Institutional Aspects ◽  
Biosafety Evaluation

Brazil is the second largest producer of genetically modified crops (GM crops) and the National Technical Commission on Biosafety (CTNBio) the decision making agency on this matter. The country uses Risk Analysis (RA) and project EIA as tools for biosafety evaluation. This paper aims to review the appropriateness of these tools for evaluating the environmental impacts of GM crops, also considering institutional aspects. An overview of the process of release of GM crops in Brazil along with important operational and institutional aspects is provided. The results indicate that project EIA could be applied to GM crops in specific sites and RA could give support to the evaluation of GM crop itself. Regarding institutional issues, it is concluded that decisions should be made by the environmental bodies, and not by the CTNBio.

scholarly journals Biosafety Evaluation and Quantitative Determination of Poly(hexamethylene biguanide) (PHMB) Coated on Cellulosic Fabrics by Kubelka-Munk Equation

2021 ◽  
Author(s):  
Wen-Yi Wang ◽  
Jia-Chi Chiou ◽  
Wan-Xue Chen ◽  
Jia-Li Yu ◽  
Chi-wai Kan
Keyword(s):  
Quantitative Determination ◽  
Cotton Fabrics ◽  
Bromophenol Blue ◽  
Blue Dye ◽  
Feasible Method ◽  
Colour Strength ◽  
Low Concentrations ◽  
Cellulosic Fabric ◽  
Biosafety Evaluation

Abstract It is a challenge to determine the quantity of cationic finishing agents on the surface of cellulosic fabrics. Herein, we report a direct and feasible method by Kubelka-Munk equation to quantify the cationic poly (hexamethylene biguanide) hydrochloride (PHMB) adsorbed onto cotton fabrics based on the principle of formation of a stable blue dye between PHMB and bromophenol blue sodium (BPB). The adsorption of PHMB onto cotton fabrics was first investigated and the maximum adsorption of PHMB was found to be around 8 mg per gram of cotton fabric. After being dyed with BPB, colour strength shows a positive correlation with PHMB at low concentrations (< 2400 mg/L). A linear relationship with a high correlation (C(PHMB) = (K/S—0.7411)/3.4517, R2 = 0.9983) was thus established between colour strength and PHMB concentration. However, this equation should fulfill four requirements for quantifying PHMB: (1) the distribution of PHMB on the surface of cellulosic fabric should be in the form of a monolayer with the content less than 5.3 mg/g; (2) an excess of BPB dyebath should be applied; (3) the dyeing should come to equilibrium; and (4) the fabrics should be evenly dyed. Moreover, MTT assay results indicate that excess PHMB coated on cotton fabrics can cause cytotoxicity and the quantity of PHMB should not exceed 4.62 mg per gram of cotton fabrics for the purpose of biosafety. The sample can be considered non-cytotoxic if the K/S value is lower than 13.2 after dyeing with BPB.

Synthesis, structures, and ESI-mass studies of silver(I) derivatives of imidazolidine-2-thiones: Antimicrobial potential and biosafety evaluation

2018 ◽  
Vol 178 ◽  
pp. 18-31 ◽  
Author(s):  
Jaspreet K. Aulakh ◽  
Tarlok S. Lobana ◽  
Henna Sood ◽  
Daljit S. Arora ◽  
Victoria A. Smolinski ◽  
...  
Keyword(s):  
Antimicrobial Potential ◽  
Derivatives Of ◽  
Biosafety Evaluation

Biosafety Evaluation of Nanoscaled Porous Energy Materials

2015 ◽  
pp. 239-268
Author(s):  
S. Bashir ◽  
Z. Luo ◽  
B. Martinez ◽  
U. Okakpu ◽  
J. Liu
Keyword(s):  
Energy Materials ◽  
Biosafety Evaluation

Sensitive and Specific Detection of Breast Cancer Lymph Node Metastasis Through Dual-Modality Magnetic Particle Imaging and Fluorescence Molecular Imaging: a Preclinical Evaluation

2021 ◽  
Author(s):  
Guorong Wang ◽  
Guangyuan Shi ◽  
Yu Tian ◽  
Lingyan Kong ◽  
Ning Ding ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Magnetic Particle ◽  
Cancer Targeting ◽  
Node Metastasis ◽  
Magnetic Particle Imaging ◽  
Particle Imaging ◽  
Fluorescence Molecular Imaging ◽  
Biosafety Evaluation

Abstract Purpose: A sensitive and specific imaging method to detect metastatic cancer cells in lymph nodes (LNs) to detect the early-stage breast cancer is urgently needed. The purpose of this study was to investigate a novel breast cancer-targeting and tumour microenvironment ATP-responsive superparamagnetic iron oxide (SPIOs) imaging probe that was developed to detect lymph node metastasis (LNMs) through fluorescence molecular imaging (FMI) and magnetic particle imaging (MPI). The imaging nanoprobe comprised of SPIOs conjugated with breast cancer-targeting peptides (CREKA) and an ATP-responsive DNA aptamer (dsDNA-Cy5.5), abbreviated as SPIOs@A-T. Methods: SPIOs@A-T was synthesised and characterized for its imaging properties, targeting ability and toxicity in vitro. Mice with metastatic lymph node (MLN) of breast cancer were established to evaluate the FMI and MPI imaging strategy in vivo. Healthy mice with normal lymph node (NLN) were used as control group. Histological examination and biosafety evaluation were performed for further assessment. Results: After injection with SPIO@A-T, the obvious high fluorescent intensity and MPI signal were observed in MLN group than those in NLN group. MPI could also complement the limitation of imaging depth from FMI, thus could detect MLN more sensitively. The combination of the imaging strengths of FMI and MPI ensured the detection of breast cancer metastases with high sensitivity and specificity, thereby facilitating the precision differentiation of malignant from benign LNs. Besides, the biosafety evaluation results showed SPIO@A-T had good biocompatibility. Conclusion: Due to the superior properties of tumour-targeting, detection specificity, and biosafety, the SPIOs@A-T imaging probe in combination with FMI and MPI can provide a promising novel method for the early and precise detection of LNMs in clinical practice.

Comparative muscle proteomics/phosphoproteomics analysis provides new insight for the biosafety evaluation of fat-1 transgenic cattle

2017 ◽  
Vol 26 (5) ◽  
pp. 625-638 ◽  
Author(s):  
Xiangbo Xin ◽  
Xinfeng Liu ◽  
Xin Li ◽  
Xiangbin Ding ◽  
Shuping Yang ◽  
...  
Keyword(s):  
Transgenic Cattle ◽  
Muscle Proteomics ◽  
Biosafety Evaluation

Graphene-Based Anticancer Nanosystem and Its Biosafety Evaluation Using a Zebrafish Model

2013 ◽  
Vol 14 (2) ◽  
pp. 358-366 ◽  
Author(s):  
Chen-Wei Liu ◽  
Feng Xiong ◽  
Hui-Zhen Jia ◽  
Xu-Li Wang ◽  
Han Cheng ◽  
...  
Keyword(s):  
Zebrafish Model ◽  
Biosafety Evaluation
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