Ultrasound-Assisted Extraction of Phenolic Acids, Flavonols, and Flavan-3-ols From Muscadine Grape Skins and Seeds Using Natural Deep Eutectic Solvents and Predictive Modelling by Artificial Neural Networking

2021 ◽  
Author(s):  
Mohammed A. Alrugaibah ◽  
Taylor L. Washington ◽  
Yavuz Yagiz ◽  
Liwei Gu
Keyword(s):  
Phenolic Acids ◽  
Predictive Modelling ◽  
Deep Eutectic Solvents ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Natural Deep Eutectic Solvents ◽  
Artificial Neural Networking ◽  
Grape Skins ◽  
Ultrasound Assisted ◽  
Artificial Neural

scholarly journals Natural deep eutectic solvents as new green solvents to extract anthraquinones from Rheum palmatum L.

RSC Advances ◽  
2018 ◽  
Vol 8 (27) ◽  
pp. 15069-15077 ◽  
Author(s):  
Y. C. Wu ◽  
P. Wu ◽  
Y. B. Li ◽  
T. C. Liu ◽  
L. Zhang ◽  
...  
Keyword(s):  
Deep Eutectic Solvents ◽  
Green Solvents ◽  
Ultrasound Assisted Extraction ◽  
Rheum Palmatum ◽  
Assisted Extraction ◽  
Natural Deep Eutectic Solvents ◽  
Ultrasound Assisted

Natural deep eutectic solvents ultrasound-assisted extraction (NADES-UAE) was applied to extract total anthraquinones from Rheum palmatum L.

Natural deep eutectic solvents and ultrasound-assisted extraction: Green approaches for extraction of wine lees anthocyanins

2017 ◽  
Vol 102 ◽  
pp. 195-203 ◽  
Author(s):  
Tomislav Bosiljkov ◽  
Filip Dujmić ◽  
Marina Cvjetko Bubalo ◽  
Janez Hribar ◽  
Rajko Vidrih ◽  
...  
Keyword(s):  
Deep Eutectic Solvents ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Natural Deep Eutectic Solvents ◽  
Ultrasound Assisted

scholarly journals A Sustainable Approach for Extracting Non-Extractable Phenolic Compounds from Mangosteen Peel Using Ultrasound-Assisted Extraction and Natural Deep Eutectic Solvents

2021 ◽  
Vol 11 (12) ◽  
pp. 5625
Author(s):  
Merichel Plaza ◽  
Gloria Domínguez-Rodríguez ◽  
Cristina Sahelices ◽  
María Luisa Marina
Keyword(s):  
Phenolic Compounds ◽  
Deep Eutectic Solvents ◽  
Extraction Time ◽  
Size Exclusion ◽  
Total Phenolic ◽  
Ultrasound Assisted Extraction ◽  
Mangosteen Peel ◽  
Assisted Extraction ◽  
Natural Deep Eutectic Solvents ◽  
Ultrasound Assisted

Mangosteen (Garcinia mangostana L.) peel is a potential source of phenolic compounds with beneficial properties. Natural deep eutectic solvents (NaDES) have been considered an environmentally friendly and cheap alternative to conventional organic solvents. In this work, a green extraction methodology was developed using ultrasound-assisted extraction (UAE) and NaDES for the extraction of antioxidant non-extractable polyphenols (NEPs) from mangosteen peel. To select the best NaDES to extract NEPs from mangosteen peel, seven NaDES were studied. Antioxidant capacity and total phenolic and proanthocyanidin contents were determined for the extracts. The molecular weights for the NEPs present in those extracts were evaluated by size exclusion chromatography. Experimental results showed that choline chloride–lactic acid (1:2) was the NaDES allowing the highest antioxidant proanthocyanidin content in the extracts. A Box–Behnken experimental design was employed to optimize the main parameters in UAE with NaDES: water percentage, ultrasound amplitude, and extraction time. The optimal extraction conditions were 18.8% (v/v) water, 60% ultrasound amplitude, and 15 min as the extraction time. In addition, the cytotoxicity of the NEP extracts obtained under optimal extraction conditions was evaluated. Results indicated for the first time that the use of NaDES in combination with UAE could be a sustainable alternative for the extraction of antioxidant NEPs from mangosteen peel for important applications in the food, pharmaceutical, agrochemical, and cosmetic fields, as the extracts presented low cytotoxicity.

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