Smokeless Tobacco Use and Oral Potentially Malignant Disorders Among People Living with HIV (PLHIV) in Pune, India: Implications for Oral Cancer Screening in PLHIV

2021 ◽  
Author(s):  
Ivan Marbaniang ◽  
Samir Joshi ◽  
Shashikala Sangle ◽  
Samir Khaire ◽  
Rahul Thakur ◽  
...  
Keyword(s):  
Cancer Screening ◽  
Oral Cancer ◽  
Smokeless Tobacco ◽  
People Living With Hiv ◽  
Oral Potentially Malignant Disorders ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Oral Cancer Screening ◽  
Smokeless Tobacco Use ◽  
Living With Hiv

scholarly journals Validity and Reliability of Intraoral Camera with Fluorescent Aids for Oral Potentially Malignant Disorders Screening in Teledentistry

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Sirikanlaya Vetchaporn ◽  
Wetchayan Rangsri ◽  
Jitjiroj Ittichaicharoen ◽  
Pimduen Rungsiyakull
Keyword(s):  
Cancer Screening ◽  
Oral Cancer ◽  
White Light ◽  
Initial Diagnosis ◽  
Combination Method ◽  
Validity And Reliability ◽  
Oral Potentially Malignant Disorders ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Oral Cancer Screening

There is limited documentation of using fluorescence images in oral potentially malignant disorders (OPMDs) and oral cancer screening through the field of teledentistry. This study aims to develop and evaluate the validity and reliability of the intraoral camera with the combination method of autofluorescence and LED white light used for OPMDs and oral cancer screening in teledentistry. The intraoral camera with fluorescent aids, which uses a combined method of both autofluorescence and LED white light, was developed before the device was evaluated for validity and reliability as a OPMDs screening tool for teledentistry. All lesions of thirty-four OPMD patients underwent biopsy for definitive diagnosis and were examined by an oral medicine specialist. Both images under autofluorescent and LED white light mode captured from the device were sent online and interpreted for the initial diagnosis and dysplastic features in addition to being compared to the direct clinical examination and histopathological findings. The combination method was also compared with autofluorescence method alone. The device provided good image quality, which was enough for initial diagnosis. Using the combination method, sensitivity, specificity, PPV, and NPV of the device via teledentistry were 87.5%, 84.6%, 63.6%, and 95.7%, respectively, which were higher than autofluorescence method alone in every parameter. The concordance of dysplastic lesion was 85.29% and 79.41% for category of lesion. The validity and reliability results of the combination method for the screening of dysplasia in OPMDs were higher than autofluorescent method alone. The intraoral camera with fluorescent aids for the OPMDs screening can be utilized for screening via teledentistry.

scholarly journals Prevalence and Correlates of Snuff Use, and its Association With Tuberculosis, Among Women Living With HIV in South Africa

2018 ◽  
Vol 21 (8) ◽  
pp. 1087-1092 ◽  
Author(s):  
Jessica L Elf ◽  
Ebrahim Variava ◽  
Sandy Chon ◽  
Limakatso Lebina ◽  
Katlego Motlhaoleng ◽  
...  
Keyword(s):  
South Africa ◽  
Tobacco Use ◽  
Smokeless Tobacco ◽  
People Living With Hiv ◽  
Potential Health ◽  
Adjusted Analysis ◽  
Women Living With Hiv ◽  
Urine Cotinine ◽  
Smokeless Tobacco Use ◽  
Living With Hiv

Abstract Introduction A higher proportion of people living with HIV (PLWH) smoke compared to the general population, but little information exists about the prevalence and correlates of smokeless tobacco use among PLWH. In South Africa, dry powdered tobacco is inhaled nasally as snuff. Methods A cross-sectional survey among PLWH attending three HIV clinics was conducted. Snuff use was assessed via self-report and urine cotinine. Results Given the low (3%) prevalence of snuff use among men, analysis was restricted to n = 606 nonsmoking women living with HIV. Half (n = 298, 49%) were snuff users, the majority of whom (n = 244, 84%) had a positive urine cotinine test. In adjusted analysis, snuff use was negatively associated with higher education (relative risk [RR] 0.55; 95% confidence interval [CI]: 0.39, 0.77) and mobile phone ownership (RR 0.83; 95% CI: 0.71, 0.98), and positively associated with ever having tuberculosis (TB) (RR 1.22; 95% CI: 1.03, 1.45). In adjusted analysis, with current TB as the outcome, snuff use was marginally statistically significantly associated with a twofold increase in odds of a current TB diagnosis (odds ratio [OR] 1.99; 95% CI: 0.98, 4.15). Discussion A high proportion of nonsmoking South African women living with HIV use snuff, which was a risk factor for TB. Additional research is needed to understand the relationship between snuff, TB, and other potential health risks. Implications PLWH have a higher prevalence of smoking than their seronegative peers, but there is a paucity of research on smokeless tobacco use in this population, especially in low-resource settings. TB is the leading cause of death among PLWH, and with improvements to HIV treatment and care, PLWH are at greater risk of tobacco-related diseases. We report an extremely high prevalence of snuff use among women living with HIV in South Africa. Further, in this population snuff use is positively associated with ever having a TB diagnosis, as well as currently having TB.

scholarly journals Scope of Conventional and Fractal Morphometry in Oral Potentially Malignant Disorders and Oral Cancer

2021 ◽  
Vol 10 (6) ◽  
Author(s):  
Paresh Kumar Behera ◽  
Diksha Mohapatra
Keyword(s):  
Image Analysis ◽  
Fractal Dimension ◽  
Oral Cancer ◽  
World Health ◽  
Oral Potentially Malignant Disorders ◽  
Potentially Malignant Disorders ◽  
Risk Of Malignancy ◽  
Potentially Malignant ◽  
Health Organization

World Health Organization (WHO) defined the terminology ‘Oral Potentially malignant disorders’ (OPMD) as the presence of risk of malignancy in a lesion or condition either during the time of initial diagnosis or at a future date with the commonly accepted prevalence of 1–5%. All OPMDs may not transform into malignancy, many factors have been explored which effectively assess the risk of malignant transformation in OPMDs including many clinical, pathological and molecular factors. Qualitative & experimental factors of different cells in cytological preparations and/or biopsy specimens are reliable parameters for pathologists. The analysis and assessment of histological units can be enhanced by image analysis assisted by a computer that can be used for statistical comparisons. Fractal geometry is considered to be an ideal method of image analysis in quantitative microscopy & histopathology. Fractal dimension analysis is not only limited to determining cell and tumour types but can also be used for determining cellular behaviours in vitro such as cell migration, apoptosis and cellular differentiation, which can be a useful characterization of oral cancer lines and further help in the treatment planning. Keywords: Oral Cancer, Oral Potentially Malignant Disorders (OPMDs), Conventional morphometry, Fractal Dimension, Photomicrograph

The Clinical Presentation of Oral Potentially Malignant Disorders

2016 ◽  
Vol 5 (1) ◽  
pp. 52-57
Author(s):  
Neal J Mccormick ◽  
Peter J Thomson ◽  
Marco Carrozzo
Keyword(s):  
Oral Cancer ◽  
Clinical Presentation ◽  
Screening Programme ◽  
Survival Rates ◽  
Oral Potentially Malignant Disorders ◽  
Clinical Appearance ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
The Uk ◽  
Dental Appointments

Early detection of oral cancer improves survival rates significantly, however, the incidence of oral cancer has continued to rise in the UK – between 2002–2012, it increased by more than 30%.1 There is currently no national screening programme for oral cancer, so undertaking a full examination of the oral mucosa during routine dental appointments is vital. Although strong evidence is still lacking, oral cancer is thought to be preceded by oral potential malignant disorders (OPMDs) or oral precancerous diseases. These mainly present as white/red lesions within the mouth and their clinical appearance can be challenging to diagnose accurately, which can lead to them being misdiagnosed as negligible problems. Dentists must keep up to date with OPMDs detection and ensure they are capable of correctly recognising lesions that carry a potential risk. This paper aims to provide a brief overview on OPMDs, highlighting potentially malignant disorders as they may present to the practitioner, showing their typical clinical appearance, and suggesting differential diagnosis and clinical management in dental practice.

EARLY DIAGNOSIS PROGRAM FOR ORAL POTENTIALLY MALIGNANT DISORDERS AND ORAL CANCER IN A CHRONIC ALCOHOLICS AND DRUG USERS

2017 ◽  
Vol 124 (2) ◽  
pp. e156
Author(s):  
DANIELA BRITO BASTOS ◽  
VITOR BONETTI VALENTE ◽  
BRUNA AMÉLIA MOREIRA SARAFIM DA SILVA ◽  
SUZY ELAINE NOBRE DE FREITAS ◽  
ANA RITA ALBUQUERQUE ZITO ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Early Diagnosis ◽  
Drug Users ◽  
Oral Potentially Malignant Disorders ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant
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