scholarly journals Appraising research policy instrument mixes: a multicriteria mapping study in six European countries of diagnostic innovation to manage antimicrobial resistance

2021 ◽  
Author(s):  
Josie Coburn ◽  
Frédérique Bone ◽  
Andy Stirling ◽  
Michael M. Hopkins ◽  
Jorge Mestre Ferrandiz ◽  
...  
2021 ◽  
Vol 50 (4) ◽  
pp. 104140
Author(s):  
Josie Coburn ◽  
Frederique Bone ◽  
Michael M. Hopkins ◽  
Andy Stirling ◽  
Jorge Mestre-Ferrandiz ◽  
...  

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V Saint ◽  
A Mohsenpour ◽  
C Mühling ◽  
K Bozorgmehr

Abstract Background Antimicrobial resistance (AMR) is a considerable threat to modern medicine and global health. Inequity, gender and social determinants of health (SDH) have a significant impact on health and health services, including in relation to AMR. Despite this, there is a lack of systematic focus on these dimensions in AMR research, policy and practice. We aimed to scope and review the existing evidence related to the equity, gender and SDH considerations for AMR globally through a systematic, iterative approach. Methods We conducted a scoping review by searching PubMed, Web of Science and CINAHL for empirical research on AMR in humans, with consideration of equity, gender or SDH, published in English between January 2000 and September 2019. In a two-stage process, we analysed full texts to extract information about explicit and then implicit references to equity, gender or SDH. Results The search yielded 4628 articles after removing 578 duplicates. 737 articles were analysed with explicit reference to equity, gender or SDH in title or abstract. Preliminary results show that 93.2% of these studies mentioned gender but mostly meaning biological sex (90.8%) rather than its social construct. Articles on equity (6.0%) and SDH (1.1%) reported on associations between AMR rates and income and non-income dimensions of inequality, health system issues and disadvantaged subpopulations within countries. Other articles in this category explored public and policy discourse or approaches for AMR (0.8%) and equity issues for AMR-related R&D (0.7%). These results combined with the PROGRESS-Plus acronym informed the subsequent analysis of the 4628 articles for implicit considerations of equity, gender and SDH. Conclusions Despite casting a wide net, we found relatively little research explicitly considering equity, gender and SDH aspects of AMR especially at a systematic or structural level. This reflects an important gap in the current understanding of and efforts to tackle AMR. Key messages We conducted a scoping review on equity, gender and social determinants considerations of AMR that indicates limited research on these important aspects of the social and structural drivers of AMR. Further research on these aspects is essential to inform the design of effective policy and practice interventions that target vulnerable groups and address structural inequities.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Rachid Y. Yahiaoui ◽  
Hester J. Bootsma ◽  
Casper D. J. den Heijer ◽  
Gerlinde N. Pluister ◽  
W. John Paget ◽  
...  

2018 ◽  
Vol 1 (1) ◽  
pp. 86-97
Author(s):  
Jorma Sipilä

The presented article is an attempt to draw attention to the economiccontexts of the functioning of families in Europe. The author presentsvarious types of financial support for families using the examples fromselected European countries. The idea of paying the mother for lookingafter her children at home is analysed in detail.


2020 ◽  
Vol Volume 13 ◽  
pp. 957-993 ◽  
Author(s):  
Octavio Mesa Varona ◽  
Katerina Chaintarli ◽  
Berit Muller-Pebody ◽  
Muna F Anjum ◽  
Tim Eckmanns ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0135094 ◽  
Author(s):  
Evelien M. E. van Bijnen ◽  
John Paget ◽  
Elly S. M. de Lange-de Klerk ◽  
Casper D. J. den Heijer ◽  
Ann Versporten ◽  
...  

2008 ◽  
Vol 50 (1) ◽  
Author(s):  
Rene S Hendriksen ◽  
Dik J Mevius ◽  
Andreas Schroeter ◽  
Christopher Teale ◽  
Danièle Meunier ◽  
...  

2019 ◽  
Vol 18 (1) ◽  
pp. 69-79 ◽  
Author(s):  
David J. Mott ◽  
Grace Hampson ◽  
Martin J. Llewelyn ◽  
Jorge Mestre-Ferrandiz ◽  
Michael M. Hopkins

Abstract Background Novel diagnostics are needed to manage antimicrobial resistance (AMR). Patient preferences are important in determining whether diagnostic tests are successful in practice, but there are few data describing the test attributes which matter most to patients. We elicited patients’ preferences for attributes of diagnostic tests that could be used to reduce unnecessary antibiotic use in primary care across seven European countries. Methods We used an online stated preference survey, including a discrete choice experiment (DCE). The DCE explored how patients make trade-offs between three key attributes of diagnostic tests: the speed that results were available, confidence in the test results, and how convenient it is to take the test. Individuals were eligible to complete the survey if they had taken antibiotics within the last 2 years and were resident in Germany, Italy, Spain, France, Greece, the Netherlands or the United Kingdom (UK). Results In total, 988 respondents completed the survey. The DCE responses illustrated that speed was the least important attribute in most countries. Responses from Germany and the Netherlands indicated that confidence was most important in these countries. Responses from the UK, France, Spain and Italy showed convenience as the most important attribute in these countries. Two attributes, confidence and convenience, were jointly favoured by respondents in Greece. Conclusion Patients in different European countries do not have the same preferences for the attributes of diagnostic tests to manage AMR in primary care. Failure to account for such differences during test development could reduce test uptake, result in continued overuse of antibiotics, and hamper marketisation.


2019 ◽  
Vol 11 (6) ◽  
pp. 1800 ◽  
Author(s):  
Gabriela Cioca ◽  
Florentina-Daniela Munteanu

The impact of the antibiotics in the environment is not well understood yet. Moreover, the total amount of antibiotics that are ending up in the environment as solid waste is not known and cannot be rigorously determined as many variables are influencing the determination of their concentration. The present article is focused on the estimation of the amount of non-prescribed antibiotics that are used in different European countries. Particular attention is paid to the class of beta-lactams, as they are responsible for a considerate share of the antimicrobial resistance. The primary purpose was the estimation of the quantity of non-prescribed antibiotics that might reach the environment as solid waste. For the present study, we used the ECDC and EUROSTAT reported data.


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