Does the Lightning Process Training Programme Reduce Chronic Fatigue in Adolescent and Young Adult Cancer Survivors? A Mixed-Methods Pilot Study

2021 ◽  
Author(s):  
Lena Fauske ◽  
Oyvind Sverre Bruland ◽  
Alv Andreas Dahl ◽  
Aase Myklebostad ◽  
Silje Endresen Reme
Keyword(s):  
Mixed Methods ◽  
Young Adult ◽  
Pilot Study ◽  
Cancer Survivors ◽  
Chronic Fatigue ◽  
Training Programme ◽  
Adolescent And Young Adult ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
Young Adult Cancer

scholarly journals Does the Lightning Process Training Programme Reduce Chronic Fatigue in Adolescent and Young Adult Cancer Survivors? A Mixed-Methods Pilot Study

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4076
Author(s):  
Lena Fauske ◽  
Øyvind S. Bruland ◽  
Alv A. Dahl ◽  
Aase Myklebostad ◽  
Silje E. Reme
Keyword(s):  
Mixed Methods ◽  
Young Adult ◽  
Cancer Survivors ◽  
Chronic Fatigue ◽  
Training Programme ◽  
Adolescent And Young Adult ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
Young Adult Cancer

Background: We report on a pilot intervention study exploring the efficacy of the Lightning Process® training programme for reducing chronic fatigue and improving health-related quality of life in cancer survivors. Methods: 13 adolescent and young adult cancer survivors previously treated for sarcoma or Hodgkin lymphoma were enrolled. A mixed-methods approach was applied. This involved the use of five validated patient-reported outcome measure (PROM) questionnaires at baseline and the three- and six-month follow-up points to obtain quantitative data. Semi-structured interviews were conducted after the intervention with emphasis on the participants’ experiences and outcomes. A reflexive thematic analysis was applied to the transcripts. Results: A significant reduction (p < 0.001) in the total fatigue score from baseline to the three- and six-month follow-up points was documented. The correlation coefficients between the various PROMs at baseline and the six-month follow-up point indicated considerable overlap between the measures. The qualitative findings of the interviews corresponded well with the PROM findings. Most participants experienced both less fatigue and explicit improvement in their energy level. The aspects of the intervention found to be particularly helpful were the theoretical rationale and the coping techniques mediated. Conclusion: These encouraging results here reported should be of interest to the general oncological community, although they require confirmation through a larger and controlled study.

scholarly journals Individualized exercise and the health of the AYA cancer survivor population

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Adam Corya ◽  
Jacob Conroy ◽  
Abigail Bolt ◽  
Jessica Ricks ◽  
Nicholas Kelly ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Young Adult ◽  
Pilot Study ◽  
Cancer Survivors ◽  
Exercise Intervention ◽  
Adolescent And Young Adult ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
Young Adult Cancer

Background + Hypothesis Adolescent and young adult cancer survivors (AYACS: ages 15-39) have an 84.5% five-year survival rate.(1) AYACS have a 10 times greater risk to develop cardiac disease compared to healthy peers.(2) This is in part due to their lower physical activity.(3) Structured exercise in adult cancer survivors improves strength, fatigue, VO2, and antioxidant levels and it decreases markers of cellular damage(4, 5). AYACS could benefit similarly, reducing long-term health effects. Although evidence suggests exercise is beneficial in older cancer survivors, this has not been demonstrated in AYACS. We hypothesized that a 12-week one-on-one multi-modal, community-based exercise program would improve AYACS outcomes compared to baseline or inactive AYACS. The current study hopes to demonstrate the feasability of an exercise intervention in a community setting within Indianapolis. Methods Six individuals were included in a feasibility trial for a larger pilot study of 374 participants. On day 1, baseline assessments were performed for experimental outcomes: body composition, strength, flexibility, VO2peak, balance, plasma biomarkers, PA, psychological health, health-related quality of life, and fatigue. Mini reassessments were performed at week 5, measuring strength and VO2peak with an estimated 1-rep maximum and 6-minute Walk Test respectively; in the larger pilot study participants will be reassessed at weeks 12 and 24. Participants train for 60 minutes (20 cardio, 30 weights, 10 stretching) 3 times a week for 12 weeks, one-on-one with a cancer exercise specialist. Results The average change in VO2peak was +25.3% and in strength was +17.5% (no statistical analysis). Adherence was 90.9%. Conclusion + Potential impact This trial suggests the feasibility of a pilot larger study. The greatest limitation was that the population sample was not within the AYACS age range. However, as the goal was to show feasibility rather than to prove efficacy, the sample gave useful information. Sources (1-5) 1. Anderson C, Smitherman AB, Nichols HB. Conditional relative survival among long-term survivors of adolescent and young adult cancers. Cancer. 2018;124(14):3037-43. 2. Armstrong GT, Kawashima T, Leisenring W, Stratton K, Stovall M, Hudson MM, et al. Aging and risk of severe, disabling, life-threatening, and fatal events in the childhood cancer survivor study. J Clin Oncol. 2014;32(12):1218-27. 3. Wu YP, Yi J, McClellan J, Kim J, Tian T, Grahmann B, et al. Barriers and Facilitators of Healthy Diet and Exercise Among Adolescent and Young Adult Cancer Survivors: Implications for Behavioral Interventions. J Adolesc Young Adult Oncol. 2015;4(4):184-91. 4. Repka CP, Hayward R. Oxidative Stress and Fitness Changes in Cancer Patients after Exercise Training. Med Sci Sports Exerc. 2016;48(4):607-14. 5. Repka CP, Hayward R. Effects of an Exercise Intervention on Cancer-Related Fatigue and Its Relationship to Markers of Oxidative Stress. Integr Cancer Ther. 2018;17(2):503-10.

scholarly journals Lasting effects of cancer and its treatment on employment and finances in adolescent and young adult cancer survivors

Cancer ◽  
2019 ◽  
Vol 125 (11) ◽  
pp. 1908-1917 ◽  
Author(s):  
Tyler G. Ketterl ◽  
Karen L. Syrjala ◽  
Jacqueline Casillas ◽  
Linda A. Jacobs ◽  
Steven C. Palmer ◽  
...  
Keyword(s):  
Young Adult ◽  
Cancer Survivors ◽  
Adolescent And Young Adult ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
Young Adult Cancer

scholarly journals Accelerated aging among childhood, adolescent, and young adult cancer survivors is evidenced by increased expression of p16 INK4a and frailty

Cancer ◽  
2020 ◽  
Vol 126 (22) ◽  
pp. 4975-4983
Author(s):  
Andrew B. Smitherman ◽  
William A. Wood ◽  
Natalia Mitin ◽  
Vanessa L. Ayer Miller ◽  
Allison M. Deal ◽  
...  
Keyword(s):  
Young Adult ◽  
Cancer Survivors ◽  
Accelerated Aging ◽  
Adolescent And Young Adult ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
P16 Ink4a ◽  
Young Adult Cancer

Pain and Intolerance of Uncertainty among Adolescent and Young Adult Cancer Survivors

2021 ◽  
Vol 22 (5) ◽  
pp. 611
Author(s):  
Vivek Tanna ◽  
Sarah J. Cunningham ◽  
Pamela Simon ◽  
Sheri L. Spunt ◽  
Lidia Schapira ◽  
...  
Keyword(s):  
Young Adult ◽  
Cancer Survivors ◽  
Intolerance Of Uncertainty ◽  
Adolescent And Young Adult ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
Young Adult Cancer
Sign in / Sign up

Export Citation Format

Share Document