Mitochondrial DNA as a Biomarker for Acute Central Serous Chorioretinopathy: A Case-Control Study

2021 ◽  
Author(s):  
Noriyasu Hashida ◽  
Kazunobu Asao ◽  
Chikako Hara ◽  
Andrew J. Quantock ◽  
Kazuichi Maruyama ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Central Serous Chorioretinopathy ◽  
Case Control Study ◽  
Case Control ◽  
Acute Central Serous Chorioretinopathy ◽  
Control Study

Maternal serum mitochondrial DNA (mtDNA) levels are elevated in preeclampsia – A matched case-control study

2018 ◽  
Vol 14 ◽  
pp. 195-199 ◽  
Author(s):  
Julian Marschalek ◽  
Peter Wohlrab ◽  
Johannes Ott ◽  
Johann Wojta ◽  
Walter Speidl ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Case Control Study ◽  
Case Control ◽  
Maternal Serum ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals A Case-Control Study of Peripheral Blood Mitochondrial DNA Copy Number and Risk of Renal Cell Carcinoma

PLoS ONE ◽  
2012 ◽  
Vol 7 (8) ◽  
pp. e43149 ◽  
Author(s):  
Mark P. Purdue ◽  
Jonathan N. Hofmann ◽  
Joanne S. Colt ◽  
Mirjam Hoxha ◽  
Julie J. Ruterbusch ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Mitochondrial Dna ◽  
Cell Carcinoma ◽  
Peripheral Blood ◽  
Renal Cell ◽  
Copy Number ◽  
Case Control Study ◽  
Case Control ◽  
Mitochondrial Dna Copy Number ◽  
Control Study

scholarly journals Twenty-four-hour Blood Pressure Monitoring in Central Serous Chorioretinopathy – A Case-control Study

2013 ◽  
Vol 07 (01) ◽  
pp. 42
Author(s):  
Pradeep Venkatesh ◽  
Vikas Jain ◽  
Satpal Garg ◽  
◽  
◽  
...  
Keyword(s):  
Blood Pressure ◽  
Central Serous Chorioretinopathy ◽  
Case Control Study ◽  
Blood Pressure Monitoring ◽  
Case Control ◽  
Mean Difference ◽  
National Committee ◽  
The Mean ◽  
The Difference ◽  
Control Study

Purpose:A case-control study to explore the diurnal variation of blood pressure (BP) in patients with central serous chorioretinopathy (CSCR).Methods:One-hundred patients (50 cases with central serous chorioretinopathy and 50 age- and sex-matched controls) participated in this study. Twenty-four-hour BP was recorded by auscultatory method using manual standard mercury sphygmomanometer by a single, trained observer. Hypertension was categorised according to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-VII) classification.Results:Mean systolic BP (SBP) and diastolic BP (DBP) in cases and controls were 123.4 mmHg (range 112.3–134.6), 81.72 mmHg (range 73.0–90.5); 118.33 mmHg (range 108.4–128.2); and 77.50 mmHg (range 71.4–83.6), respectively. The difference in SBP and DBP was statistically significant at p=0.02 for the former and p=0.006 for the latter. The mean difference in maximum and minimum SBP in cases was 18 (±15.81) mmHg versus 9.04 (±3.08) mmHg in controls (p=0.001). Mean difference for DBP in cases was 15.16 (±7.86) mmHg versus 9.16 (±3.68) mmHg in controls (0.001). On the JNC-VII classification scale for hypertension, 66 % of cases were found to be pre-hypertensive (60 %) or hypertensive (6 %). Comparative figures for controls were pre-hypertension (30 %) and hypertension (2 %). The mean SBP and DBP was consistently higher in patients with CSCR compared with controls over the entire 24-hour period. The difference in variation between maximum and minimum SBP and DBP was also found to be statistically significant between the groups.Conclusion:A significant correlation exists between higher values BP and central serous chorioretinopathy. Screening of CSCR patients for pre-hypertension may be useful in decreasing the risk of progression to established hypertension, with its associated risks.

Temperament Profile in Patients with Central Serous Chorioretinopathy: A Case-Control Study

2014 ◽  
Vol 24 (3) ◽  
pp. 392-395 ◽  
Author(s):  
Małgorzata Piskunowicz ◽  
Marcin Jaracz ◽  
Hanna Lesiewska ◽  
Grażyna Malukiewicz ◽  
Marzenna Brożek-Pestka ◽  
...  
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Risk Factors for Central Serous Chorioretinopathy: A Case-Control Study

Medicina ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 81-93
Author(s):  
G. R. Khasanova ◽  
◽  
D. R. Аgliullin ◽  
E. A. Abdulaeva ◽  
L. R. Kagirova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Arterial Hypertension ◽  
Central Serous Chorioretinopathy ◽  
Protective Factor ◽  
Case Control Study ◽  
Significant Risk ◽  
Case Control ◽  
Industrial City ◽  
Corticosteroid Drugs ◽  
Control Study

Aim of the study: Assessment of the influence of potential risk factors on the development of central serous chorioretinopathy in a large industrial city. Materials and Methods: Case-control study of persons aged 18 years and older. The study group included 100 patients with central serous chorioretinopathy, confirmed by optical coherence tomography, and controls – 100 patients without central serous chorioretinopathy. The groups are comparable in gender and age. Interviewing of patients was carried out according to the developed questionnaire, including 33 questions. One-way and multivariate analysis of the results using logistic regression was carried out. Statistical data processing was carried out using Microsoft Office Excel 2010, Jamovi programs, R – Studio statistical package, OpenEpi online calculators (http://www.openepi.com). Results: The following risk factors for CSC were identified: taking corticosteroid drugs in the last year – OR 13.5; 95% CI 3.4-53.2 and the presence of arterial hypertension – OR 8.3; 95% CI 1.3-54.1. Intake of antihypertensive drugs and psychotropic drugs from the group of anxiolytics were statistically significant factors in the "prevention" of the development of CSC (OR 0.1; 95% CI 0.02-0.9 and OR 0.01; 95% CI 0.0003− 0.5), respectively. The presence of myopia also proved to be a protective factor for CSC –OR 0.3; 95% CI 0.14-0.8. Conclusion: In a case-control study, significant risk factors for CSC for the population of a large industrial city were arterial hypertension and the use of corticosteroid drugs. The presence of myopia is associated with a lower incidence of CSC.

scholarly journals Intima-Media Thickness Measurements of the Common Carotid Artery in Patients with Central Serous Chorioretinopathy: A Case-Control Study

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Kobra Nasrollahi ◽  
Amirhossein Farahi ◽  
Fatemeh Paknazar ◽  
Mohamadreza Akhlaghi ◽  
Farhad Fazel ◽  
...  
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Case Control Study ◽  
Intima Media Thickness ◽  
Case Control ◽  
Control Group ◽  
Media Thickness ◽  
Left And Right ◽  
The Difference ◽  
The Right ◽  
Control Study

Purpose. To evaluate the intima-media thickness (IMT) of the left and right common carotid arteries (CCA) as an indicator of subclinical atherosclerosis in patients with central serous chorioretinopathy (CSCR). Methods. This was a case-control study involving patients with CSCR and a matched healthy control group. The mean and difference of the left and right CCA IMT were determined and compared between the two groups using carotid duplex high-resolution B-mode ultrasound equipment. Results. The study enrolled 32 CSCR patients (68.8% female, mean age 38.22 ± 5.42 years) and 32 controls (65.6% female, mean age 39.56 ± 5.33 years). The difference in common carotid IMT between the right and left sides was significantly greater in the CSCR group than in the control group ( p < 0.001 ). Additionally, according to logistic regression analysis, patients with CSCR had a greater chance of having differences in IMT between the two sides when compared to the control group (OR: 1.29, 95% CI: 1.09–1.52). Conclusion. Our findings indicated that in the CSCR group, the difference between the right and left sides of CCA IMT was significantly greater than in the control group.

scholarly journals Use of plasma mitochondrial DNA levels for determining disease severity and prognosis in pediatric sepsis: a case control study

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Hai peng Yan ◽  
Miao Li ◽  
Xiu lan Lu ◽  
Yi min Zhu ◽  
Wen-xian Ou-yang ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Disease Severity ◽  
Case Control Study ◽  
Case Control ◽  
Pediatric Sepsis ◽  
Control Study

scholarly journals Comprehensive analysis of common and rare mitochondrial DNA variants in elite Japanese athletes: a case–control study

2013 ◽  
Vol 58 (12) ◽  
pp. 780-787 ◽  
Author(s):  
Eri Mikami ◽  
Noriyuki Fuku ◽  
Qing-Peng Kong ◽  
Hideyuki Takahashi ◽  
Nao Ohiwa ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Case Control Study ◽  
Case Control ◽  
Comprehensive Analysis ◽  
Dna Variants ◽  
Mitochondrial Dna Variants ◽  
Control Study
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