Willingness to Receive COVID-19 Vaccination Among People Living With HIV and AIDS in China: A Nationwide Online Survey

2021 ◽  
Author(s):  
Xiaojie Huang ◽  
Maohe Yu ◽  
Gengfeng Fu ◽  
Guanghua Lan ◽  
Linghua Li ◽  
...  
2021 ◽  
Author(s):  
Xiaojie Huang ◽  
Maohe Yu ◽  
Gengfeng Fu ◽  
Guanghua Lan ◽  
Linghua Li ◽  
...  

BACKGROUND HIV infection is a significant independent risk factor for both severe COVID-19 presentation at hospital admission and in-hospital mortality. Available information has suggested that people living with HIV and AIDS (PLWHA) could benefit from COVID-19 vaccination. However, there is a dearth of evidence on willingness to receive COVID-19 vaccination among PLWHA. OBJECTIVE The aim of this study was to investigate willingness to receive COVID-19 vaccination among a national sample of PLWHA in China. METHODS This cross-sectional online survey investigated factors associated with willingness to receive COVID-19 vaccination among PLWHA aged 18 to 65 years living in eight conveniently selected Chinese metropolitan cities between January and February 2021. Eight community-based organizations (CBOs) providing services to PLWHA facilitated the recruitment. Eligible PLWHA completed an online survey developed using a widely used encrypted web-based survey platform in China. We fitted a single logistic regression model to obtain adjusted odds ratios (aORs), which involved one of the independent variables of interest and all significant background variables. Path analysis was also used in the data analysis. RESULTS Out of 10,845 PLWHA approached by the CBOs, 2740 completed the survey, and 170 had received at least one dose of the COVID-19 vaccine. This analysis was performed among 2570 participants who had never received COVID-19 vaccination. Over half of the participants reported willingness to receive COVID-19 vaccination (1470/2570, 57.2%). Perceptions related to COVID-19 vaccination were significantly associated with willingness to receive COVID-19 vaccination, including positive attitudes (aOR 1.11, 95% CI 1.09-1.12; <i>P</i>&lt;.001), negative attitudes (aOR 0.96, 95% CI 0.94-0.97; <i>P</i>&lt;.001), perceived support from significant others (perceived subjective norm; aOR 1.53, 95% CI 1.46-1.61; <i>P</i>&lt;.001), and perceived behavioral control (aOR 1.13, 95% CI 1.11-1.14; <i>P</i>&lt;.001). At the interpersonal level, receiving advice supportive of COVID-19 vaccination from doctors (aOR 1.99, 95% CI 1.65-2.40; <i>P</i>&lt;.001), CBO staff (aOR 1.89, 95% CI 1.51-2.36; <i>P</i>&lt;.001), friends and/or family members (aOR 3.22, 95% CI 1.93-5.35; <i>P</i>&lt;.001), and PLWHA peers (aOR 2.38, 95% CI 1.85-3.08; <i>P</i>&lt;.001) was associated with higher willingness to receive COVID-19 vaccination. The overall opinion supporting COVID-19 vaccination for PLWHA on the internet or social media was also positively associated with willingness to receive COVID-19 vaccination (aOR 1.59, 95% CI 1.31-1.94; <i>P</i>&lt;.001). Path analysis indicated that interpersonal-level variables were indirectly associated with willingness to receive COVID-19 vaccination through perceptions (β=.43, 95% CI .37-.51; <i>P</i>&lt;.001). CONCLUSIONS As compared to PLWHA in other countries and the general population in most parts of the world, PLWHA in China reported a relatively low willingness to receive COVID-19 vaccination. The internet and social media as well as interpersonal communications may be major sources of influence on PLWHA’s perceptions and willingness to receive COVID-19 vaccination.


2020 ◽  
Author(s):  
Yong Yu ◽  
Zijue Chang ◽  
Xiuya Liu ◽  
Yu Lu

Abstract Background: A cross-sectional survey was conducted from the two perspectives of the incidence, type, help-seeking situation of PLWHA(People living with HIV and AIDS)rejected by medical staff and the willingness of medical staff to diagnose and treat PLWHA to analyze the realistic problem of PLWHA and AIDS rejected by medical staff under the current Chinese cultural background.Methods: 1500 people were selected from PLWHA users in the WeChat work account of a Center for Disease Control and Prevention(CDC), and 1000 medical staff were selected from a third-class hospital in Guangxi, China. The self-compiled general information questionnaire and PLWHA medical rejection questionnaire were used to conduct a one-to-one WeChat online survey on PLWHA. A questionnaire on HIV/AIDS clinical knowledge, a questionnaire on HIV/AIDS attitude, and a questionnaire on the willingness to diagnose and treat PLWHA with clinical surgery were used to conduct a face-to-face survey on the selected medical staff.Results: 1146 valid PLWHA samples and 890 medical staff samples were obtained. 30.2% (346/1146) of HIV-infected/AIDS patients had experienced refusal from medical staff when visiting a hospital for non-HIV/AIDS-related diseases since the diagnosis of HIV+; 17.1% (196/1146) of HIV-infected/AIDS patients had been rejected by medical staff in the hospital due to other diseases in the past 12 months and 10.8% (124/1146) had been rejected in clinical surgeries; after receiving a refusal, 58.2% (114/196) of the HIV-infected/AIDS patients never asked for help, while only 37.8% (74/196) of the refused patients were resolved accordingly. Only 38.7% of medical staff clearly expressed their willingness to provide surgical treatment or post-operative nursing services for HIV-infected/AIDS patients. After controlling other factors, the answer accuracy of HIV/AIDS-related knowledge [odds ratio (OR)=2.41, 95% confidence interval (CI): 1.31, 4.43] and the attitudes towards HIV/AIDS (OR=6.74, 95%CI: 3.59, 12.66) were the influencing factors for medical staff's willingness to diagnosis and treat HIV-infected /AIDS patients with clinical surgery.Conclusions: Rejection by the medical staff is a common phenomenon during the treatment of HIV-infected/AIDS patients in China and the willingness of medical staff to diagnose and treat HIV-infected/AIDS patients is relatively weak.


2010 ◽  
Vol 28 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Laura Louie ◽  
Nopporn Pathanapornpandh ◽  
Unchalee Pultajuk ◽  
Robert Kaplan ◽  
Ian Hodgson ◽  
...  

Acupuncture in combination with antiretroviral therapies is a potentially useful treatment for HIV-related symptom relief in resource-poor settings. Traditional Chinese medicine has a long history of being used to enhance immune function. In the setting of HIV, Chinese traditional medicine allows for symptom treatment without adding extra medications to a complex drug regime. This paper provides details of a project at Mae On Hospital in rural northern Thailand where allopathic/conventional treatments are used in tandem with acupuncture. A preliminary evaluation of the project suggests that an integrated approach to symptom relief is viewed positively by respondents receiving acupuncture, though further studies are required to confirm the association between acupuncture and symptom relief. The project also demonstrates the feasibility of developing a cost-effective acupuncture programme using local healthcare staff.


2020 ◽  
Vol 47 (3) ◽  
pp. 190-200
Author(s):  
M.G. Mustapha ◽  
G.M. Ashir ◽  
A.I. Rabasa ◽  
A.G. Farouk ◽  
H.A. Elechi ◽  
...  

Tuberculosis (TB) is an important infectious disease of public health concern. The effects of TB on children in terms of morbidity and mortality is  more than that of adults. These may not be unconnected with the differences in characteristics and peculiarities of the disease in children. Tuberculosis in children is usually primary, paucibacillary, characterized by difficulties in diagnosis of both drug susceptible and resistant TB associated with poor uptake of preventive therapy for those with latent infection, contacts and people living with HIV and AIDS (PLWHA) in most  developing countries.While significant similarities exist between spectrum of TB occurring in adults and children, the characteristics and peculiarities of childhood TB may be unknown to policy makers and some clinicians, hence giving it less focus in control measures. The aim of this review is to highlight some of the characteristics and peculiarities of TB in children using PubMed/PubMed Central (PMC) and MEDLINE databases searched for relevant search strings from December, 2018 to September, 2019. Appropriate hard copies of books and journal articles were also  included. Conclusion: While the management of TB in children is characterized by difficulties due to both peculiarities of children and the disease;  with detailed clinical assessment and examination of necessary specimen in addition to strict adherence to the guidelines of the national TB control  program, more cases of TB in children can be prevented, diagnosed, treated and reported. 


HIV ◽  
2020 ◽  
pp. 103-106
Author(s):  
David E. Barker

Herpes Zoster is a distressingly common occurrence in people living with HIV and AIDS. But what happens when a patient has multiple recurrences and stops responding to therapeutic and suppressive acyclovir analogs. What clues should lead to a reconsideration of the diagnosis and treatment.


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