scholarly journals Diffusion Tensor Imaging of the Median Nerve: A Systematic Review and Meta-Analysis of Normal Values in Asymptomatic Adults and How They Change in Carpal Tunnel Syndrome

2021 ◽  
Author(s):  
Djamila Rojoa ◽  
Firas Raheman ◽  
Joseph Rassam ◽  
Ryckie Wade
Keyword(s):  
Systematic Review ◽  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Normal Values ◽  
Diffusion Tensor ◽  
Meta Analysis ◽  
Tunnel Syndrome

scholarly journals Diffusion Tensor Imaging of the Median Nerve: A Systematic Review and Meta-Analysis of Normal Values in Asymptomatic Adults and How They Change in Carpal Tunnel Syndrome 

2021 ◽  
Author(s):  
Djamila Rojoa ◽  
Firas Raheman ◽  
Joseph Rassam ◽  
Ryckie George Wade
Keyword(s):  
Systematic Review ◽  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Diffusion Tensor ◽  
Meta Analysis ◽  
Mean Diffusivity ◽  
Mean Difference ◽  
Tunnel Syndrome

Abstract Background: Carpal tunnel syndrome (CTS) leads to distortion of axonal architecture, demyelination and fibrosis within the median nerve. Diffusion tensor imaging (DTI) characterises tissue microstructure and generates reproducible proxy measures of nerve ‘health’ which are sensitive to myelination, axon diameter, fibre density and organisation. This meta-analysis summarises the normal DTI values of the median nerve, and how they change in CTS.Methods: This systematic review included studies reporting DTI of the median nerve at the level of the wrist in adults. The primary outcome was to determine the normal fractional anisotropy (FA) and mean diffusivity (MD) of the median nerve. Secondarily, we show how the FA and MD differ between asymptomatic adults and patients with CTS, and how these differences are independent of the acquisition methods.Results: 32 studies of 2643 wrists, belonging to 1575 asymptomatic adults and 1068 patients with CTS were included. The normal FA was 0·58 (95% CI 0·56, 0·59) and the normal MD was 1·138 x10-3 mm2/s (95% CI 1·101, 1·174). Patients with CTS had a significantly lower FA than controls (mean difference 0·12 [95% CI 0·09, 0·16]). Similarly, the median nerve of patients with CTS had a significantly higher mean diffusivity (mean difference 0·16 mm2/s x10-3 [95% CI 0·05, 0·27]). The differences were independent of experimental factors.Conclusion: We provide summary estimates of the normal FA and MD of the median nerve in asymptomatic adults. Furthermore, we show that diffusion throughout the length of the median nerve becomes more isotropic in patients with CTS.

scholarly journals Meta-analysis of the normal diffusion tensor imaging values of the median nerve and how they change in carpal tunnel syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Djamila Rojoa ◽  
Firas Raheman ◽  
Joseph Rassam ◽  
Ryckie G. Wade
Keyword(s):  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Diffusion Tensor ◽  
Meta Analysis ◽  
Mean Diffusivity ◽  
Mean Difference ◽  
Fiber Density ◽  
Tunnel Syndrome

AbstractCarpal tunnel syndrome (CTS) leads to distortion of axonal architecture, demyelination and fibrosis within the median nerve. Diffusion tensor imaging (DTI) characterises tissue microstructure and generates reproducible proxy measures of nerve ‘health’ which are sensitive to myelination, axon diameter, fiber density and organisation. This meta-analysis summarises the normal DTI values of the median nerve, and how they change in CTS. This systematic review included studies reporting DTI of the median nerve at the level of the wrist in adults. The primary outcome was to determine the normal fractional anisotropy (FA) and mean diffusivity (MD) of the median nerve. Secondarily, we show how the FA and MD differ between asymptomatic adults and patients with CTS, and how these differences are independent of the acquisition methods. We included 32 studies of 2643 wrists, belonging to 1575 asymptomatic adults and 1068 patients with CTS. The normal FA was 0.58 (95% CI 0.56, 0.59) and the normal MD was 1.138 × 10–3 mm2/s (95% CI 1.101, 1.174). Patients with CTS had a significantly lower FA than controls (mean difference 0.12 [95% CI 0.09, 0.16]). Similarly, the median nerve of patients with CTS had a significantly higher mean diffusivity (mean difference 0.16 × 10–3 mm2/s [95% CI 0.05, 0.27]). The differences were independent of experimental factors. We provide summary estimates of the normal FA and MD of the median nerve in asymptomatic adults. Furthermore, we show that diffusion throughout the length of the median nerve becomes more isotropic in patients with CTS.

Systematic review and meta-analysis of surgical options for recurrent or persistent carpal tunnel syndrome: simple decompression versus coverage of the median nerve

2021 ◽  
pp. 175319342110017
Author(s):  
Saskia F. de Roo ◽  
Philippe N. Sprangers ◽  
Erik T. Walbeehm ◽  
Brigitte van der Heijden
Keyword(s):  
Systematic Review ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Carpal Tunnel Release ◽  
Meta Analysis ◽  
Surgical Techniques ◽  
Open Release ◽  
Flap Coverage ◽  
Tunnel Syndrome

We performed a systematic review on the success of different surgical techniques for the management of recurrent and persistent carpal tunnel syndrome. Twenty studies met the inclusion criteria and were grouped by the type of revision carpal tunnel release, which were simple open release, open release with flap coverage or open release with implant coverage. Meta-analysis showed no difference, and pooled success proportions were 0.89, 0.89 and 0.85 for simple open carpal tunnel release, additional flap coverage and implant groups, respectively. No added value for coverage of the nerve was seen. Our review indicates that simple carpal tunnel release without additional coverage of the median nerve seems preferable as it is less invasive and without additional donor site morbidity. We found that the included studies were of low quality with moderate risk of bias and did not differentiate between persistent and recurrent carpal tunnel syndrome.

scholarly journals Acupuncture and related therapies for carpal tunnel syndrome: A protocol for systematic review and Bayesian network meta-analysis

2021 ◽  
Author(s):  
Zhiyuan Bian ◽  
◽  
Jie Yu ◽  
Mingqi Tu ◽  
Binjun Liao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Meta Analysis ◽  
Complementary Therapy ◽  
Prominent Component ◽  
Review Question ◽  
Tunnel Syndrome ◽  
Surgical Treatments

Review question / Objective: We aim to compare the efficacy and safety of different acupuncture and related therapies for carpal tunnel syndrome (CTS) using systematic review and network meta-analysis (NMA). Condition being studied: CTS is a symptomatic condition caused by compression of the median nerve within the carpal tunnel. Patients with CTS typically report paresthesia or pain in distribution of median nerve distal to the wrist. Diverse non-surgical treatments and surgical decompression have been used in the management of CTS. Acupuncture, a prominent component of traditional Chinese medicine (TCM), has also been practiced when treating CTS as a complementary therapy. However, the relative treatment effects of different acupuncture methods for CTS are unclear.

scholarly journals Utility of MRI Diffusion Tensor Imaging in Carpal Tunnel Syndrome: A Meta-Analysis

2016 ◽  
Vol 22 ◽  
pp. 736-742 ◽  
Author(s):  
Hong Wang ◽  
Jingxu Ma ◽  
Liping Zhao ◽  
Yunling Wang ◽  
Xiaowen Jia
Keyword(s):  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Diffusion Tensor ◽  
Meta Analysis ◽  
Tunnel Syndrome

Pre- and post-operative diffusion tensor imaging of the median nerve in carpal tunnel syndrome

2012 ◽  
Vol 22 (6) ◽  
pp. 1310-1319 ◽  
Author(s):  
Jaana Hiltunen ◽  
Erika Kirveskari ◽  
Jussi Numminen ◽  
Nina Lindfors ◽  
Harry Göransson ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Diffusion Tensor ◽  
Tunnel Syndrome

Evaluation of median nerve by shear wave elastography and diffusion tensor imaging in carpal tunnel syndrome

2018 ◽  
Vol 101 ◽  
pp. 59-64 ◽  
Author(s):  
Mehmet Cingoz ◽  
Sedat Giray Kandemirli ◽  
Deniz Can Alis ◽  
Cesur Samanci ◽  
Guzin Cakir Kandemirli ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Shear Wave ◽  
Carpal Tunnel ◽  
Diffusion Tensor ◽  
Shear Wave Elastography ◽  
Tunnel Syndrome ◽  
And Diffusion

Diffusion tensor imaging and tractography of the median nerve in carpal tunnel syndrome: preliminary results

2008 ◽  
Vol 18 (10) ◽  
pp. 2283-2291 ◽  
Author(s):  
C. Khalil ◽  
C. Hancart ◽  
V. Le Thuc ◽  
C. Chantelot ◽  
D. Chechin ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Diffusion Tensor ◽  
Preliminary Results ◽  
Tunnel Syndrome
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