Coronavirus, Compulsory Licensing, and Collaboration: Analyzing the 2020 Global Vaccine Response with 20/20 Hindsight

2021 ◽  
Author(s):  
Arjun Padmanabhan
Keyword(s):  
Vaccine Response ◽  
Compulsory Licensing

Additional nutritional considerations for preconditioning beef calves.

EDIS ◽  
2017 ◽  
Vol 2017 (4) ◽  
Author(s):  
Philipe Moriel
Keyword(s):  
Average Daily Gain ◽  
Beef Steers ◽  
Labor Costs ◽  
Vaccine Response ◽  
Negative Effects ◽  
Beef Calves ◽  
Supplemental Feed ◽  
Concentrate Supplementation ◽  
Protein Supply ◽  
Daily Gain

Calves can be preconditioned using a wide variety of supplemental feed ingredients. However, feed ingredient selection is not the only factor to consider during a preconditioning process. Increasing the protein supply to stressed, preconditioning beef steers led to greater growth performance, and increased immune response to vaccination during a 42-day preconditioning period. Producers should not reduce the frequency of concentrate supplementation during the entire preconditioning period as it might lead to poorer vaccine response and average daily gain (consequently, less calf value at sale). However, a gradual reduction of frequency of supplementation is a supplementation strategy that can overcome these negative effects on growth and immunity, and allows producers to save on feeding and labor costs without producing lighter calves that have weaker immune responses.  

scholarly journals Psychological and Behavioral Predictors of Vaccine Efficacy: Considerations for COVID-19

2021 ◽  
pp. 174569162198924
Author(s):  
Annelise A. Madison ◽  
M. Rosie Shrout ◽  
Megan E. Renna ◽  
Janice K. Kiecolt-Glaser
Keyword(s):  
Risk Factors ◽  
Side Effects ◽  
Vaccine Efficacy ◽  
Psychological Factors ◽  
Behavioral Interventions ◽  
Vulnerable Groups ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Vaccine Response ◽  
The Impact

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates are being evaluated, with the goal of conferring immunity on the highest percentage of people who receive the vaccine as possible. It is noteworthy that vaccine efficacy depends not only on the vaccine but also on characteristics of the vaccinated. Over the past 30 years, a series of studies has documented the impact of psychological factors on the immune system’s vaccine response. Robust evidence has demonstrated that stress, depression, loneliness, and poor health behaviors can impair the immune system’s response to vaccines, and this effect may be greatest in vulnerable groups such as the elderly. Psychological factors are also implicated in the prevalence and severity of vaccine-related side effects. These findings have generalized across many vaccine types and therefore may be relevant to the SARS-CoV-2 vaccine. In this review, we discuss these psychological and behavioral risk factors for poor vaccine responses, their relevance to the COVID-19 pandemic, as well as targeted psychological and behavioral interventions to boost vaccine efficacy and reduce side effects. Recent data suggest these psychological and behavioral risk factors are highly prevalent during the COVID-19 pandemic, but intervention research suggests that psychological and behavioral interventions can increase vaccine efficacy.

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