Chlamydial Infections (Intracellular Infection) in the Development of Bronchitis (Review)

2021 ◽  
Author(s):  
Z.E. Kudratova ◽  
L.A. Mukhamadieva ◽  
F.S. Khamedova ◽  
G.R. Rustamova
Keyword(s):  
Intracellular Infection ◽  
Chlamydial Infections

scholarly journals Development of a Fluorescent Tool for Studying Legionella bozemanae Intracellular Infection

2021 ◽  
Vol 9 (2) ◽  
pp. 379
Author(s):  
Breanne M. Head ◽  
Christopher I. Graham ◽  
Teassa MacMartin ◽  
Yoav Keynan ◽  
Ann Karen C. Brassinga
Keyword(s):  
Growth Kinetics ◽  
Legionella Pneumophila ◽  
Fluorescent Protein ◽  
Disease Incidence ◽  
Acanthamoeba Castellanii ◽  
Infection Model ◽  
Intracellular Infection ◽  
Green Fluorescent

Legionnaires’ disease incidence is on the rise, with the majority of cases attributed to the intracellular pathogen, Legionella pneumophila. Nominally a parasite of protozoa, L. pneumophila can also infect alveolar macrophages when bacteria-laden aerosols enter the lungs of immunocompromised individuals. L. pneumophila pathogenesis has been well characterized; however, little is known about the >25 different Legionella spp. that can cause disease in humans. Here, we report for the first time a study demonstrating the intracellular infection of an L. bozemanae clinical isolate using approaches previously established for L. pneumophila investigations. Specifically, we report on the modification and use of a green fluorescent protein (GFP)-expressing plasmid as a tool to monitor the L. bozemanae presence in the Acanthamoeba castellanii protozoan infection model. As comparative controls, L. pneumophila strains were also transformed with the GFP-expressing plasmid. In vitro and in vivo growth kinetics of the Legionella parental and GFP-expressing strains were conducted followed by confocal microscopy. Results suggest that the metabolic burden imposed by GFP expression did not impact cell viability, as growth kinetics were similar between the GFP-expressing Legionella spp. and their parental strains. This study demonstrates that the use of a GFP-expressing plasmid can serve as a viable approach for investigating Legionella non-pneumophila spp. in real time.

scholarly journals 010 Polycytotoxic T cells protect against intracellular infection

2016 ◽  
Vol 136 (5) ◽  
pp. S2
Author(s):  
S.J. Balin ◽  
S. Stenger ◽  
M. Pellegrni ◽  
M. Ochoa ◽  
M. Schenk ◽  
...  
Keyword(s):  
T Cells ◽  
Intracellular Infection

Test-of-Cure for Asymptomatic Genital Chlamydial Infections in Women

1992 ◽  
Vol 19 (3) ◽  
pp. 133-136 ◽  
Author(s):  
A. SCHITZ HJALMAR ◽  
A. CSÁNGÓ PÉTER
Keyword(s):  
Chlamydial Infections

scholarly journals Human Chlamydial Infections

1980 ◽  
Vol 56 (1) ◽  
pp. 58-58 ◽  
Author(s):  
J D Oriel
Keyword(s):  
Chlamydial Infections
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