scholarly journals Epidemiology of Herpes Simplex Virus Type 2 in Asia: A Systematic Review, Meta-Analysis, and Meta-Regression

2021 ◽  
Author(s):  
Sawsan AlMukdad ◽  
Manale Harfouche ◽  
Anja Wettstein ◽  
Laith J. Abu-Raddad
2015 ◽  
Vol 212 (1) ◽  
pp. 8-17 ◽  
Author(s):  
A. Esber ◽  
R. D. Vicetti Miguel ◽  
T. L. Cherpes ◽  
M. A. Klebanoff ◽  
M. F. Gallo ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Yu peng Wu ◽  
Dan dan Sun ◽  
Yun Wang ◽  
Wen Liu ◽  
Jun Yang

Objective.The aim of our study was to evaluate the relation of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infection with the risk of atherosclerosis (AS).Methods.A systematic literature search was performed through three electronic databases. The pooled odds ratio (OR) and corresponding 95% confidence interval (CI) were used to assess the effect of HSV-1 and HSV-2 infection on AS risk.Results.17 studies were available for meta-analysis of HSV-1 infection and AS risk and seven studies for meta-analysis of HSV-2 infection and AS risk. Subjects exposed to HSV-1 infection exhibited an increased risk of AS (OR = 1.77; 95% CI: 1.40–2.23;P<0.001). And consistent elevated AS risks for HSV-1 positive subjects were found in all subgroup analysis of disease type, region, male proportion, and age. HSV-2 positive subjects demonstrated significantly increased AS risk (OR = 1.37; 95% CI: 1.13–1.67;P<0.005). In subgroup analysis, elevated AS risks were only observed in myocardial ischemia group, male proportion >60% group, and age ≤60-year-old group.Conclusion.Our meta-analysis indicated that HSV-1 and HSV-2 infection could increase the risk of contracting AS.


2021 ◽  
Vol 35 ◽  
pp. 100876
Author(s):  
Manale Harfouche ◽  
Farah M. Abu-Hijleh ◽  
Charlotte James ◽  
Katharine J. Looker ◽  
Laith J. Abu-Raddad

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